User:Kgoldthorn

CACAO Spring 2014

Status	Page	Date/Time	GO Term (Aspect)	Reference	Evidence	Notes	Links
unacceptable	ECO57:TUS	2014-01-31 17:34:59 CST	GO:0003677 DNA binding (F)	PMID:11206551	ECO:0000317 genomic context evidence used in manual assertion	Seeded From UniProt Figure 2. EDL933 genes orientation and segments are represented by color. K and O- islands of 50 bp or longer were assigned KI or OI numbers.	challenge
unacceptable	HUMAN:TTBK1	2014-01-31 17:56:25 CST	GO:0016301 kinase activity (F)	PMID:17344846	ECO:0000314 direct assay evidence used in manual assertion	Seeded From UniProt Figure 3. The difference in selection pressure between ten protein kinase. Previous kinases were linked to cancer genes such as tyrosine kinase and serine/threonine kinases. Evidence proves that other subclasses of kinases are contributing to the development of cancer.	challenge
unacceptable	HUMAN:TTBK2	2014-01-31 18:22:01 CST	GO:0004672 protein kinase activity (F)	PMID:21548880	ECO:0000314 direct assay evidence used in manual assertion	Figure 4. Cells expressing GFP-TTBK2 were treated to induce the expression of TTBK2. Flourcent imaging was performed using a confocal microscope. Mutations showed an increase in TTBK2 as well as protein kinase activity.	challenge

acceptable:0
unacceptable:3
requires_changes:0
flagged:0

Status	Author,Group	Page	GO Term (Aspect)	Reference	Evidence	Links	Page history
updatedbyinstructor	Tnguyen2, Team Food Rewards	?	GO:0043032 - positive regulation of macrophage activation (Figure 6C: Analysis of RT-PCR showed that enforced expression of Ifi204 favors M-CSF-dependent macrophage differentiation in in FD-Fms cells.)	PMID:16244109	IDA: Inferred from Direct Assay	challenge	C: 2 fixed by Zielin64
updatedbyinstructor	Jcameron, Team Food Rewards	RAT:MK08	GO:0097050 - type B pancreatic cell apoptotic process (P)	PMID:24475223	ECO:0000315 mutant phenotype evidence used in manual assertion	challenge	C: 3
unacceptable	Relledge, Team Blot Blot Wstrn Baby	PIG:PEPA	GO:0008233 - peptidase activity (F)	PMID:2195218	ECO:0000314 direct assay evidence used in manual assertion	challenge	C: 1
unacceptable	Relledge, Team Blot Blot Wstrn Baby	MOUSE:TNR16	GO:0009986 - cell surface (C)	PMID:3815101	ECO:0000314 direct assay evidence used in manual assertion	challenge	C: 1
updatedbyinstructor	Kyoung, Team Pnut Butter Squares	HUMAN:BRCA1	GO:0033147 - negative regulation of intracellular estrogen receptor signaling pathway (P)	PMID:17505062	ECO:0000315 mutant phenotype evidence used in manual assertion	challenge	C: 3 fixed by Grevever

0 annotations fixed by Kgoldthorn