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User:MidwestB

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My Annotations

StatusPageDate/TimeGO Term (Aspect)ReferenceEvidenceNotesLinks
acceptableMOUSE:FGF92013-02-19 10:42:44 CSTGO:0001654 eye development (P)PMID:21858205ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 1 shows that an allele of this product causes reduced lens thickness and axial length but an increase in anterior chamber thickness in both male and female mice.

challenge
acceptableMOUSE:Q543D22013-02-21 10:00:47 CSTGO:0030199 collagen fibril organization (P)PMID:10092650ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 3 shows that fibromodulin-null mice have abnormal morphology in their collagen fiber bundles

challenge
acceptableMOUSE:LUM2013-02-21 10:48:22 CSTGO:0032914 positive regulation of transforming growth factor beta1 production (P)PMID:21931815ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 3 shows that lumican deficient mice resulted in reduced TGF-β1 production

challenge

acceptable:3
unacceptable:0
requires_changes:0
flagged:0

Annotations challenged by MidwestB

StatusAuthor,GroupPageGO Term (Aspect)ReferenceEvidenceLinksPage history
updatedbyinstructorML,
Team JCML
HUMAN:WNT5AGO:1900020 - positive regulation of protein kinase C activity (P)PMID:12086864ECO:0000315 mutant phenotype evidence used in manual assertionchallengeC: 1

fixed by MidwestB
updatedbyinstructorML,
Team JCML
MOUSE:FZD5GO:0031077 - post-embryonic camera-type eye development (P)PMID:18832390ECO:0000315 mutant phenotype evidence used in manual assertionchallengeC: 3
updatedbyinstructorKathrynmartin,
Team M Squared
HUMAN:ATG7GO:0051607 - defense response to virus (P)PMID:23290079ECO:0000315 mutant phenotype evidence used in manual assertionchallengeC: 2
updatedbyinstructorOptimus Prime,
Team Cybertron
9CNID:D6QUQ2GO:0051781 - positive regulation of cell division (P)PMID:21103375ECO:0000315 mutant phenotype evidence used in manual assertionchallengeC: 1

fixed by MidwestB
updatedbyinstructorDjgulizia,
Team Texas Aggies
MOUSE:WNT5AGO:0030901 - midbrain development (P)PMID:23324743ECO:0000316 genetic interaction evidence used in manual assertionchallengeC: 1

fixed by MidwestB
updatedbyinstructorMcravens,
Team Racer X
TITDI:KA156GO:0044477 - envenomation resulting in negative regulation of platelet aggregation in another organism (P)PMID:21322750ECO:0000314 direct assay evidence used in manual assertionchallengeC: 1

3 annotations fixed by MidwestB

What do the icons mean in the status column?

assessment icons.jpg