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TITDI:KA156

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Species (Taxon ID) Tityus discrepans (Venezuelan scorpion). (57059)
Gene Name(s) No Information Provided.
Protein Name(s) Potassium channel toxin alpha-KTx 15.6

Discrepin

External Links
UniProt P84777
EMBL FN392270
PDB 2AXK
PDBsum 2AXK
TCDB 8.B.8.1.1
EvolutionaryTrace P84777
GO GO:0005576
GO:0019870
GO:0006952
GO:0009405
Gene3D 3.30.30.10
InterPro IPR003614
IPR001947
Pfam PF00451
SUPFAM SSF57095
PROSITE PS01138

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0044477

envenomation resulting in negative regulation of platelet aggregation in other organism

PMID:21322750[1]

ECO:0000314

P

Fig 2

complete
CACAO 6559

involved_in

GO:0044477

envenomation resulting in negative regulation of platelet aggregation in other organism

PMID:21322750[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0019870

potassium channel inhibitor activity

PMID:15369825[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0009405

pathogenesis

PMID:15369825[2]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

PMID:15369825[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001947

C

Seeded From UniProt

complete

enables

GO:0008200

ion channel inhibitor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001947

F

Seeded From UniProt

complete

involved_in

GO:0009405

pathogenesis

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001947

P

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0964
UniProtKB-SubCell:SL-0243

C

Seeded From UniProt

complete

enables

GO:0090729

toxin activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0800

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Brazón, J et al. (2011) Tityus discrepans scorpion venom activates platelets through GPVI and a novel Src-dependent signaling pathway. Platelets 22 165-72 PubMed GONUTS page
  2. 2.0 2.1 2.2 D'Suze, G et al. (2004) Discrepin, a new peptide of the sub-family alpha-ktx15, isolated from the scorpion Tityus discrepans irreversibly blocks K+ -channels (IA currents) of cerebellum granular cells. Arch. Biochem. Biophys. 430 256-63 PubMed GONUTS page