MOUSE:FGF9

Species (Taxon ID)	Mus musculus (Mouse). (10090)
Gene Name(s)	Fgf9 (synonyms: Fgf-9)
Protein Name(s)	Fibroblast growth factor 9 FGF-9 Glia-activating factor GAF HBGF-9
External Links
UniProt	P54130
EMBL	U33535 D38258 S82023 AF144626 AF144624 AF144625 AK158782 AC125399 AC154202 CH466535 BC099872 BC099873 BC099874 BC099875 BC125237
CCDS	CCDS27164.1
RefSeq	NP_038546.2
UniGene	Mm.8846
ProteinModelPortal	P54130
SMR	P54130
DIP	DIP-6032N
PhosphoSite	P54130
PRIDE	P54130
Ensembl	ENSMUST00000022545
GeneID	14180
KEGG	mmu:14180
UCSC	uc007udx.2
CTD	2254
MGI	MGI:104723
eggNOG	NOG269410
GeneTree	ENSGT00760000118859
HOGENOM	HOG000236341
HOVERGEN	HBG007580
InParanoid	P54130
KO	K04358
OMA	GELYGSD
OrthoDB	EOG7992S1
TreeFam	TF317805
Reactome	REACT_196455 REACT_196505 REACT_196507 REACT_196536 REACT_196538 REACT_196588 REACT_198525 REACT_206694 REACT_206745 REACT_213224 REACT_220750 REACT_223993 REACT_225874 REACT_226341 REACT_230708 REACT_234357 REACT_240139 REACT_94437
NextBio	285370
PRO	PR:P54130
Proteomes	UP000000589
CleanEx	MM_FGF9
ExpressionAtlas	P54130
Genevestigator	P54130
GO	GO:0005604 GO:0005737 GO:0005615 GO:0070062 GO:0008201 GO:0001525 GO:0003214 GO:0003231 GO:0007267 GO:0002062 GO:0048566 GO:0030326 GO:0048706 GO:0008543 GO:0042472 GO:0030324 GO:0060484 GO:0008584 GO:0030238 GO:0000122 GO:0030178 GO:0001649 GO:0032927 GO:0090263 GO:0060045 GO:0051781 GO:0008284 GO:0050679 GO:0010628 GO:0043410 GO:0002053 GO:0045880 GO:0045893 GO:0030949 GO:0006606 GO:0048505 GO:0021762 GO:0060979
InterPro	IPR008996 IPR028251 IPR002209 IPR028142
PANTHER	PTHR11486 PTHR11486:SF28
PRINTS	PR00263 PR00262
SMART	SM00442
SUPFAM	SSF50353
PROSITE	PS00247

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0001654	eye development	PMID:21858205^[1]	ECO:0000315			P		Figure 1 shows that an allele of this product causes reduced lens thickness and axial length but an increase in anterior chamber thickness in both male and female mice.	complete CACAO 6607
involved_in	GO:0001654	eye development	PMID:21858205^[1]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:1905931	negative regulation of vascular smooth muscle cell differentiation involved in phenotypic switching	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2610	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:1904754	positive regulation of vascular associated smooth muscle cell migration	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2610	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:1904707	positive regulation of vascular smooth muscle cell proliferation	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P31371	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:1904707	positive regulation of vascular smooth muscle cell proliferation	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2610	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0090263	positive regulation of canonical Wnt signaling pathway	PMID:18533146^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:2135961	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0060484	lung-associated mesenchyme development	PMID:18533146^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:2135961	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0060045	positive regulation of cardiac muscle cell proliferation	PMID:15621532^[3]	ECO:0000316	genetic interaction evidence used in manual assertion	MGI:MGI:95522 MGI:MGI:95523	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0060045	positive regulation of cardiac muscle cell proliferation	PMID:15621532^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0050679	positive regulation of epithelial cell proliferation	PMID:16308329^[4]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:2135961	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0050679	positive regulation of epithelial cell proliferation	PMID:16540513^[5]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0050679	positive regulation of epithelial cell proliferation	PMID:16308329^[4]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0048706	embryonic skeletal system development	PMID:17544391^[6]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:2135961	P	results_in_development_of:(EMAPA:18468)\|results_in_development_of:(EMAPA:19143)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0048566	embryonic digestive tract development	PMID:16308329^[4]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:2135961	P	results_in_development_of:(EMAPA:16715)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0048505	regulation of timing of cell differentiation	PMID:17544391^[6]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:2135961	P	regulates_o_occurs_in:(EMAPA:17742) regulates_o_occurs_in:(CL:0000743)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045880	positive regulation of smoothened signaling pathway	PMID:16778080^[7]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:2135961	P	regulates_o_occurs_in:(EMAPA:17331) regulates_o_occurs_in:(CL:0000222)\|regulates_o_occurs_in:(EMAPA:16201) regulates_o_occurs_in:(CL:0000222)\|regulates_o_occurs_in:(EMAPA:17335) regulates_o_occurs_in:(CL:0000746)\|regulates_o_occurs_in:(EMAPA:17342) regulates_o_occurs_in:(CL:0000746)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045880	positive regulation of smoothened signaling pathway	PMID:16540513^[5]	ECO:0000314	direct assay evidence used in manual assertion		P	regulates_o_occurs_in:(EMAPA:16730) regulates_o_occurs_in:(CL:0000134)\|regulates_o_occurs_in:(EMAPA:16733) regulates_o_occurs_in:(CL:0000134)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0043410	positive regulation of MAPK cascade	GO_REF:0000008	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P36364	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0042472	inner ear morphogenesis	PMID:15328018^[8]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:2135961	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0032927	positive regulation of activin receptor signaling pathway	PMID:23034635^[9]	ECO:0000314	direct assay evidence used in manual assertion		P	regulates_o_occurs_in:(CL:0000015)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0030949	positive regulation of vascular endothelial growth factor receptor signaling pathway	PMID:17544391^[6]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:2135961	P	regulates_o_occurs_in:(EMAPA:19143) regulates_o_occurs_in:(CL:0000743)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0030326	embryonic limb morphogenesis	PMID:17576930^[10]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:2135961	P	has_participant:(EMAPA:19143)\|has_participant:(EMAPA:19106)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0030324	lung development	PMID:11493531^[11]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:2135961	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0030324	lung development	PMID:16540513^[5]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0030238	male sex determination	PMID:16700629^[12]	ECO:0000316	genetic interaction evidence used in manual assertion	MGI:MGI:98371 MGI:MGI:98660 MGI:MGI:98957	P	has_participant:(EMAPA:17383)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0030238	male sex determination	PMID:16700629^[12]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:2135961	P	has_participant:(EMAPA:17383)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0030178	negative regulation of Wnt signaling pathway	PMID:16700629^[12]	ECO:0000316	genetic interaction evidence used in manual assertion	MGI:MGI:98957	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0010628	positive regulation of gene expression	PMID:9847236^[13]	ECO:0000314	direct assay evidence used in manual assertion		P	has_regulation_target:(MGI:MGI:894670)\|has_regulation_target:(MGI:MGI:1306803)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0010628	positive regulation of gene expression	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2610	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0008584	male gonad development	PMID:16540514^[14]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:2135961	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0008584	male gonad development	PMID:15229180^[15]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:2135961	P	results_in_development_of:(EMAPA:17383)\|results_in_development_of:(EMAPA:17383)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0008543	fibroblast growth factor receptor signaling pathway	PMID:15621532^[3]	ECO:0000316	genetic interaction evidence used in manual assertion	MGI:MGI:95522 MGI:MGI:95523	P	occurs_in:(EMAPA:17331) occurs_in:(CL:0000746)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0008543	fibroblast growth factor receptor signaling pathway	PMID:16308329^[4]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:2135961	P	occurs_in:(EMAPA:16715)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0008543	fibroblast growth factor receptor signaling pathway	PMID:15229180^[15]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:2135961	P	occurs_in:(EMAPA:17383) occurs_in:(CL:0000216)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0008543	fibroblast growth factor receptor signaling pathway	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2610	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0008543	fibroblast growth factor receptor signaling pathway	GO_REF:0000008	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P31371	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0008284	positive regulation of cell population proliferation	PMID:16778080^[7]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:2135961	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0008284	positive regulation of cell population proliferation	PMID:15229180^[15]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:2135961	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0008284	positive regulation of cell population proliferation	PMID:16185683^[16]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0008284	positive regulation of cell population proliferation	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2610	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0008284	positive regulation of cell population proliferation	GO_REF:0000008	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P31371	P		Seeded From UniProt	complete
enables	GO:0008083	growth factor activity	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2610	F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0007267	cell-cell signaling	PMID:15328018^[8]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:2135961	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0006606	protein import into nucleus	PMID:15229180^[15]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:2135961	P	occurs_in:(EMAPA:17383) occurs_in:(CL:0000216) has_participant:(MGI:MGI:95523)	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2610	C		Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	GO_REF:0000008	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P31371	C		Seeded From UniProt	complete
part_of	GO:0005604	basement membrane	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2610	C		Seeded From UniProt	complete
enables	GO:0005104	fibroblast growth factor receptor binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2610	F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0002062	chondrocyte differentiation	PMID:17544391^[6]	ECO:0000316	genetic interaction evidence used in manual assertion	MGI:MGI:95522	P	occurs_in:(EMAPA:17742) regulates_o_results_in_acquisition_of_features_of:(CL:0000743)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0002062	chondrocyte differentiation	PMID:17544391^[6]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:2135961	P	occurs_in:(EMAPA:17742) regulates_o_results_in_acquisition_of_features_of:(CL:0000743)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0002053	positive regulation of mesenchymal cell proliferation	PMID:18533146^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:2135961	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0002053	positive regulation of mesenchymal cell proliferation	PMID:16308329^[4]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:2135961	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0002053	positive regulation of mesenchymal cell proliferation	PMID:18231602^[17]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0002053	positive regulation of mesenchymal cell proliferation	PMID:16540513^[5]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0002053	positive regulation of mesenchymal cell proliferation	PMID:16308329^[4]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0001649	osteoblast differentiation	PMID:17544391^[6]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:2135961	P	occurs_in:(EMAPA:18514) regulates_o_results_in_acquisition_of_features_of:(CL:0000062)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0001525	angiogenesis	PMID:17544391^[6]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:2135961	P	has_participant:(EMAPA:19143)\|has_participant:(EMAPA:16104)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0001525	angiogenesis	PMID:16778080^[7]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:2135961	P	has_participant:(EMAPA:16105)\|has_participant:(EMAPA:16201)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0001525	angiogenesis	PMID:16778080^[7]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0000122	negative regulation of transcription by RNA polymerase II	PMID:16308329^[4]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:2135961	P	occurs_in:(EMAPA:16715) occurs_in:(CL:0000134) has_regulation_target:(MGI:MGI:1099809)	Seeded From UniProt	complete
involved_in	GO:0010469	regulation of signaling receptor activity	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0008083	P		Seeded From UniProt	complete
involved_in	GO:0010469	regulation of signaling receptor activity	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0008083	P		Seeded From UniProt	complete
involved_in	GO:0010469	regulation of signaling receptor activity	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0008083	P		Seeded From UniProt	complete
involved_in	GO:0010469	regulation of signaling receptor activity	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0008083	P		Seeded From UniProt	complete
involved_in	GO:1904707	positive regulation of vascular smooth muscle cell proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P31371 ensembl:ENSP00000371790	P		Seeded From UniProt	complete
involved_in	GO:0008584	male gonad development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P31371 ensembl:ENSP00000371790	P		Seeded From UniProt	complete
involved_in	GO:0008543	fibroblast growth factor receptor signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P31371 ensembl:ENSP00000371790	P		Seeded From UniProt	complete
involved_in	GO:0008284	positive regulation of cell population proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P31371 ensembl:ENSP00000371790	P		Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P31371 ensembl:ENSP00000371790	C		Seeded From UniProt	complete
involved_in	GO:1905931	negative regulation of vascular smooth muscle cell differentiation involved in phenotypic switching	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P36364 ensembl:ENSRNOP00000015368	P		Seeded From UniProt	complete
involved_in	GO:1904754	positive regulation of vascular associated smooth muscle cell migration	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P36364 ensembl:ENSRNOP00000015368	P		Seeded From UniProt	complete
involved_in	GO:1904707	positive regulation of vascular smooth muscle cell proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P36364 ensembl:ENSRNOP00000015368	P		Seeded From UniProt	complete
involved_in	GO:0043410	positive regulation of MAPK cascade	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P36364 ensembl:ENSRNOP00000015368	P		Seeded From UniProt	complete
involved_in	GO:0010628	positive regulation of gene expression	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P36364 ensembl:ENSRNOP00000015368	P		Seeded From UniProt	complete
involved_in	GO:0008543	fibroblast growth factor receptor signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P36364 ensembl:ENSRNOP00000015368	P		Seeded From UniProt	complete
involved_in	GO:0008284	positive regulation of cell population proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P36364 ensembl:ENSRNOP00000015368	P		Seeded From UniProt	complete
enables	GO:0008083	growth factor activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P36364 ensembl:ENSRNOP00000015368	F		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P36364 ensembl:ENSRNOP00000015368	C		Seeded From UniProt	complete
part_of	GO:0005604	basement membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P36364 ensembl:ENSRNOP00000015368	C		Seeded From UniProt	complete
enables	GO:0005104	fibroblast growth factor receptor binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P36364 ensembl:ENSRNOP00000015368	F		Seeded From UniProt	complete
enables	GO:0005104	fibroblast growth factor receptor binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR028251	F		Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR028251	C		Seeded From UniProt	complete
enables	GO:0008083	growth factor activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002209	F		Seeded From UniProt	complete
involved_in	GO:0008543	fibroblast growth factor receptor signaling pathway	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR028251	P		Seeded From UniProt	complete
involved_in	GO:0060979	vasculogenesis involved in coronary vascular morphogenesis	PMID:20299672^[18]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0060045	positive regulation of cardiac muscle cell proliferation	PMID:20299672^[18]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0045893	positive regulation of transcription, DNA-templated	PMID:20299672^[18]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0003231	cardiac ventricle development	PMID:20299672^[18]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0003214	cardiac left ventricle morphogenesis	PMID:20299672^[18]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0030154	cell differentiation	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0221	P		Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0964 UniProtKB-SubCell:SL-0243	C		Seeded From UniProt	complete
enables	GO:0008083	growth factor activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0339	F		Seeded From UniProt	complete
enables	GO:0008201	heparin binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0358	F		Seeded From UniProt	complete
involved_in	GO:0051781	positive regulation of cell division	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0497	P		Seeded From UniProt	complete
involved_in	GO:0007275	multicellular organism development	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0217	P		Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 Puk, O et al. (2011) The pathologic effect of a novel neomorphic Fgf9(Y162C) allele is restricted to decreased vision and retarded lens growth. PLoS ONE 6 e23678 PubMed GONUTS page
↑ ^2.0 ^2.1 ^2.2 Yin, Y et al. (2008) An FGF-WNT gene regulatory network controls lung mesenchyme development. Dev. Biol. 319 426-36 PubMed GONUTS page
↑ ^3.0 ^3.1 ^3.2 Lavine, KJ et al. (2005) Endocardial and epicardial derived FGF signals regulate myocardial proliferation and differentiation in vivo. Dev. Cell 8 85-95 PubMed GONUTS page
↑ ^4.0 ^4.1 ^4.2 ^4.3 ^4.4 ^4.5 ^4.6 Zhang, X et al. (2006) Reciprocal epithelial-mesenchymal FGF signaling is required for cecal development. Development 133 173-80 PubMed GONUTS page
↑ ^5.0 ^5.1 ^5.2 ^5.3 White, AC et al. (2006) FGF9 and SHH signaling coordinate lung growth and development through regulation of distinct mesenchymal domains. Development 133 1507-17 PubMed GONUTS page
↑ ^6.0 ^6.1 ^6.2 ^6.3 ^6.4 ^6.5 ^6.6 Hung, IH et al. (2007) FGF9 regulates early hypertrophic chondrocyte differentiation and skeletal vascularization in the developing stylopod. Dev. Biol. 307 300-13 PubMed GONUTS page
↑ ^7.0 ^7.1 ^7.2 ^7.3 Lavine, KJ et al. (2006) Fibroblast growth factor signals regulate a wave of Hedgehog activation that is essential for coronary vascular development. Genes Dev. 20 1651-66 PubMed GONUTS page
↑ ^8.0 ^8.1 Pirvola, U et al. (2004) Fgf9 signaling regulates inner ear morphogenesis through epithelial-mesenchymal interactions. Dev. Biol. 273 350-60 PubMed GONUTS page
↑ Spiller, CM et al. (2012) Endogenous Nodal signaling regulates germ cell potency during mammalian testis development. Development 139 4123-32 PubMed GONUTS page
↑ Ha, L et al. (2007) ARF functions as a melanoma tumor suppressor by inducing p53-independent senescence. Proc. Natl. Acad. Sci. U.S.A. 104 10968-73 PubMed GONUTS page
↑ Colvin, JS et al. (2001) Lung hypoplasia and neonatal death in Fgf9-null mice identify this gene as an essential regulator of lung mesenchyme. Development 128 2095-106 PubMed GONUTS page
↑ ^12.0 ^12.1 ^12.2 Kim, Y et al. (2006) Fgf9 and Wnt4 act as antagonistic signals to regulate mammalian sex determination. PLoS Biol. 4 e187 PubMed GONUTS page
↑ Tucker, AS et al. (1999) Conserved regulation of mesenchymal gene expression by Fgf-8 in face and limb development. Development 126 221-8 PubMed GONUTS page
↑ DiNapoli, L et al. (2006) FGF9 promotes survival of germ cells in the fetal testis. Development 133 1519-27 PubMed GONUTS page
↑ ^15.0 ^15.1 ^15.2 ^15.3 Schmahl, J et al. (2004) Fgf9 induces proliferation and nuclear localization of FGFR2 in Sertoli precursors during male sex determination. Development 131 3627-36 PubMed GONUTS page
↑ Wilhelm, D et al. (2005) Sertoli cell differentiation is induced both cell-autonomously and through prostaglandin signaling during mammalian sex determination. Dev. Biol. 287 111-24 PubMed GONUTS page
↑ De Langhe, SP et al. (2008) Formation and differentiation of multiple mesenchymal lineages during lung development is regulated by beta-catenin signaling. PLoS ONE 3 e1516 PubMed GONUTS page
↑ ^18.0 ^18.1 ^18.2 ^18.3 ^18.4 Olivey, HE & Svensson, EC (2010) Epicardial-myocardial signaling directing coronary vasculogenesis. Circ. Res. 106 818-32 PubMed GONUTS page

[PMID:21858205-1] 1.0 ^1.1 Puk, O et al. (2011) The pathologic effect of a novel neomorphic Fgf9(Y162C) allele is restricted to decreased vision and retarded lens growth. PLoS ONE 6 e23678 PubMed GONUTS page

[PMID:18533146-2] 2.0 ^2.1 ^2.2 Yin, Y et al. (2008) An FGF-WNT gene regulatory network controls lung mesenchyme development. Dev. Biol. 319 426-36 PubMed GONUTS page

[PMID:15621532-3] 3.0 ^3.1 ^3.2 Lavine, KJ et al. (2005) Endocardial and epicardial derived FGF signals regulate myocardial proliferation and differentiation in vivo. Dev. Cell 8 85-95 PubMed GONUTS page

[PMID:16308329-4] 4.0 ^4.1 ^4.2 ^4.3 ^4.4 ^4.5 ^4.6 Zhang, X et al. (2006) Reciprocal epithelial-mesenchymal FGF signaling is required for cecal development. Development 133 173-80 PubMed GONUTS page

[PMID:16540513-5] 5.0 ^5.1 ^5.2 ^5.3 White, AC et al. (2006) FGF9 and SHH signaling coordinate lung growth and development through regulation of distinct mesenchymal domains. Development 133 1507-17 PubMed GONUTS page

[PMID:17544391-6] 6.0 ^6.1 ^6.2 ^6.3 ^6.4 ^6.5 ^6.6 Hung, IH et al. (2007) FGF9 regulates early hypertrophic chondrocyte differentiation and skeletal vascularization in the developing stylopod. Dev. Biol. 307 300-13 PubMed GONUTS page

[PMID:16778080-7] 7.0 ^7.1 ^7.2 ^7.3 Lavine, KJ et al. (2006) Fibroblast growth factor signals regulate a wave of Hedgehog activation that is essential for coronary vascular development. Genes Dev. 20 1651-66 PubMed GONUTS page

[PMID:15328018-8] 8.0 ^8.1 Pirvola, U et al. (2004) Fgf9 signaling regulates inner ear morphogenesis through epithelial-mesenchymal interactions. Dev. Biol. 273 350-60 PubMed GONUTS page

[PMID:23034635-9] Spiller, CM et al. (2012) Endogenous Nodal signaling regulates germ cell potency during mammalian testis development. Development 139 4123-32 PubMed GONUTS page

[PMID:17576930-10] Ha, L et al. (2007) ARF functions as a melanoma tumor suppressor by inducing p53-independent senescence. Proc. Natl. Acad. Sci. U.S.A. 104 10968-73 PubMed GONUTS page

[PMID:11493531-11] Colvin, JS et al. (2001) Lung hypoplasia and neonatal death in Fgf9-null mice identify this gene as an essential regulator of lung mesenchyme. Development 128 2095-106 PubMed GONUTS page

[PMID:16700629-12] 12.0 ^12.1 ^12.2 Kim, Y et al. (2006) Fgf9 and Wnt4 act as antagonistic signals to regulate mammalian sex determination. PLoS Biol. 4 e187 PubMed GONUTS page

[PMID:9847236-13] Tucker, AS et al. (1999) Conserved regulation of mesenchymal gene expression by Fgf-8 in face and limb development. Development 126 221-8 PubMed GONUTS page

[PMID:16540514-14] DiNapoli, L et al. (2006) FGF9 promotes survival of germ cells in the fetal testis. Development 133 1519-27 PubMed GONUTS page

[PMID:15229180-15] 15.0 ^15.1 ^15.2 ^15.3 Schmahl, J et al. (2004) Fgf9 induces proliferation and nuclear localization of FGFR2 in Sertoli precursors during male sex determination. Development 131 3627-36 PubMed GONUTS page

[PMID:16185683-16] Wilhelm, D et al. (2005) Sertoli cell differentiation is induced both cell-autonomously and through prostaglandin signaling during mammalian sex determination. Dev. Biol. 287 111-24 PubMed GONUTS page

[PMID:18231602-17] De Langhe, SP et al. (2008) Formation and differentiation of multiple mesenchymal lineages during lung development is regulated by beta-catenin signaling. PLoS ONE 3 e1516 PubMed GONUTS page

[PMID:20299672-18] 18.0 ^18.1 ^18.2 ^18.3 ^18.4 Olivey, HE & Svensson, EC (2010) Epicardial-myocardial signaling directing coronary vasculogenesis. Circ. Res. 106 818-32 PubMed GONUTS page

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MOUSE:FGF9

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