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User:ML

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My Annotations

StatusPageDate/TimeGO Term (Aspect)ReferenceEvidenceNotesLinks
updatedbyinstructorHUMAN:WNT5A2013-02-19 20:49:22 CSTGO:1900020 positive regulation of protein kinase C activity (P)PMID:12086864ECO:0000315 mutant phenotype evidence used in manual assertion

Fig. 4 A:

Wnt5a increases PKC activity. PKC activity was strongly correlated to Wnt5a expression.

challenge
updatedbyinstructorMOUSE:FZD52013-02-21 09:22:31 CSTGO:0031077 post-embryonic camera-type eye development (P)PMID:18832390ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 5


challenge
acceptableHUMAN:FZD52013-02-21 09:32:44 CSTGO:0002726 positive regulation of T cell cytokine production (P)PMID:16601243ECO:0000314 direct assay evidence used in manual assertion

Figure 6

IFN-gamma release of PBMCs was dose-dependently and significantly decreased with increasing concentrations of the anti-FZD5 antiserum

challenge
acceptableRAT:SYGP12013-02-21 11:12:14 CSTGO:0045202 synapse (C)PMID:9620694ECO:0000314 direct assay evidence used in manual assertion

Figure 5, C

Two yeast two-hybrid bait constructs were tested for interaction with full-length PSD-95 as described in Experimental Procedures. The +QTRV construct interacts strongly, whereas the −QTRV construct does not.

challenge
acceptableMOUSE:FZD52013-02-22 19:38:07 CSTGO:0048596 embryonic camera-type eye morphogenesis (P)PMID:18832390ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 4


challenge
updatedbyinstructorHUMAN:SEMG12013-02-22 20:09:06 CSTGO:1901318 negative regulation of sperm motility (P)PMID:22075473ECO:0000314 direct assay evidence used in manual assertion

Figure 3: B

As Semenogelin-1 (SEMG1) increases,

intracellular Calcium levels decrease and motility goes down.

challenge
updatedbyinstructorHUMAN:SEMG12013-02-22 20:30:25 CSTGO:0090281 negative regulation of calcium ion import (P)PMID:22075473ECO:0000314 direct assay evidence used in manual assertion

Fig 3A:

The effects of SEGM1 on PH regulates the Calcium ion import.

challenge

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unacceptable:0
requires_changes:0
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Annotations challenged by ML

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