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User:Gthaljeh

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My Annotations

StatusPageDate/TimeGO Term (Aspect)ReferenceEvidenceNotesLinks
updatedbyinstructorHUMAN:5HT3D2013-02-10 15:59:42 CSTGO:0022850 serotonin-gated cation-selective channel activity (F)PMID:17392525ECO:0000314 direct assay evidence used in manual assertion

Figure 5 illustrates a concentration-response curve that shows that the percent of maximal response from the subunit increased when presented with agonists 5-HT and mCPBG and decreased when presented with antagonists such as azasetron and ondansetron.

challenge
updatedbyinstructorHUMAN:5HT3E2013-02-10 16:04:43 CSTGO:0022850 serotonin-gated cation-selective channel activity (F)PMID:17392525ECO:0000314 direct assay evidence used in manual assertion

Figure 5 illustrates a concentration-response curve that shows that the percent of maximal response from the 5HT3E subunit increased when presented with agonists 5-HT and mCPBG and decreased when presented with antagonists such as azasetron and ondansetron.

challenge
updatedbyinstructorHUMAN:5HT3C2013-02-10 16:42:09 CSTGO:0022850 serotonin-gated cation-selective channel activity (F)PMID:17392525ECO:0000314 direct assay evidence used in manual assertion

Figure 5 illustrates a concentration-response curve where the percent of maximal response from the 5HT3C subunit increased when presented with agonists 5-HT and mCPBG and decreased when presented with antagonists azasetron and ondansetron.

challenge
acceptableHUMAN:5HT3B2013-02-10 17:15:25 CSTGO:0009986 cell surface (C)PMID:16571125ECO:0000314 direct assay evidence used in manual assertion

Figure 2 shows that subunit 5HT3B is only expressed on the cell membrane when it is co-expressed with 5HT3A

challenge
requireschangesRAT:DRD32013-02-10 17:55:23 CSTGO:0004952 dopamine neurotransmitter receptor activity (F)PMID:18424554ECO:0000314 direct assay evidence used in manual assertion

Figure two shows coimmunoprecipitation with dopamine receptor d1 in rat striatum.

challenge

acceptable:1
unacceptable:0
requires_changes:1
flagged:0

Annotations challenged by Gthaljeh

StatusAuthor,GroupPageGO Term (Aspect)ReferenceEvidenceLinksPage history
unacceptableRgruettner,
Team Science Dance
HUMAN:TBPGO:0008134 - transcription factor binding (F)PMID:22810624ECO:0000314 direct assay evidence used in manual assertionchallengeC: 4
updatedbyinstructorKpatel,
Team Llamarmy
DANRE:Q2VF27GO:0051284 - positive regulation of sequestering of calcium ion (P)PMID:23376035ECO:0000315 mutant phenotype evidence used in manual assertionchallengeC: 4

fixed by Djgulizia
unacceptableRgarcia,
Team Chalupa Batman
HUMAN:NS1BPGO:0005634 - nucleus (C)PMID:2969057ECO:0000304 author statement supported by traceable reference used in manual assertionchallengeC: 5
updatedbyinstructorJlieblich,
Team Let's Take This Outside
HUMAN:PIM1GO:0070561 - vitamin D receptor signaling pathway (P)PMID:22720752ECO:0000315 mutant phenotype evidence used in manual assertionchallengeC: 4

fixed by Reddenc1

0 annotations fixed by Gthaljeh

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