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PMID:16571125
| Citation |
Reeves, DC and Lummis, SC (2006) Detection of human and rodent 5-HT3B receptor subunits by anti-peptide polyclonal antibodies. BMC Neurosci 7:27 |
|---|---|
| Abstract |
The 5-HT3 receptor is a member of a neurotransmitter-gated ion channel family which includes nicotinic acetylcholine, GABAA, and glycine receptors. While antibodies specific for the 5-HT3A receptor subunit are plentiful, and have revealed a wealth of structural and functional information, few antisera exist for the detection of 5-HT3B receptor subunits. Here we describe the generation and characterisation of a rabbit polyclonal antiserum that specifically recognises 5-HT3B receptor subunits |
| Links |
PubMed PMC1481617 Online version:10.1186/1471-2202-7-27 |
| Keywords |
Animals; Blotting, Western; Brain Chemistry; Cell Line; Fluorescent Antibody Technique, Indirect; Humans; Immunoglobulin G/blood; Immunoglobulin G/immunology; Immunoglobulin G/isolation & purification; Immunohistochemistry; Peptides/immunology; Protein Subunits/analysis; Protein Subunits/chemistry; Protein Subunits/immunology; Rats; Receptors, Serotonin, 5-HT3/analysis; Receptors, Serotonin, 5-HT3/chemistry; Receptors, Serotonin, 5-HT3/immunology |
| edit table |
Significance
Annotations
| Gene product | Qualifier | GO Term | Evidence Code | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0009986: cell surface |
ECO:0000314: |
C |
Figure 2 shows that subunit 5HT3B is only expressed on the cell membrane when it is co-expressed with 5HT3A |
complete | ||||
|
part_of |
GO:0009986: cell surface |
ECO:0000314: direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
See also
References
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