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Category:Team All about that base

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StatusPageUserDate/TimeGO Term (Aspect)ReferenceEvidenceNotesLinks
updatedbyinstructorXENTR:F6WSJ3AWynn, Team All about that base2017-04-23 17:56:08 CDTGO:0005634 nucleus (C)PMID:20174658ECO:0000314 direct assay evidence used in manual assertion

Xenopus tropicalis CRY2. Both GFP-CRY1 and GFP-CRY2 localized in the nucleus, while GFP alone localized predominantly in the cytoplasm (Figure 4).

challenge
updatedbyinstructorMOUSE:TET1AWynn, Team All about that base2017-04-23 16:28:01 CDTGO:0048813 dendrite morphogenesis (P)PMID:26711116ECO:0000315 mutant phenotype evidence used in manual assertion

In figure 7 (C and D), Tet knockdown impairs dendritic arborization of murine cerebellar granule cells without affecting granule cell migration.

challenge
unacceptableBRADI:I1IC13AWynn, Team All about that base2017-04-23 15:24:02 CDTGO:0010321 regulation of vegetative phase change (P)PMID:27803189ECO:0000316 genetic interaction evidence used in manual assertion

In figure 7A, swn-3 delays vegetative phase change by modulating the expression of genes in the miR156-SPLs pathway.

challenge
unacceptableMOUSE:STILSMass, Team All about that base2017-04-23 15:20:17 CDTGO:0072718 response to cisplatin (P)PMID:28423708ECO:0000315 mutant phenotype evidence used in manual assertion

in figure 2(D-F), knockdown of STIL gene significantly enhanced the sensitivity to cisplatin cure

challenge
unacceptableHUMAN:CALYSATrimble, Team All about that base2017-04-23 14:05:20 CDTGO:0003824 alpha-1,3-mannosyltransferase activity (F)PMID:28087245ECO:0000247 sequence alignment evidence used in manual assertion

Figure 6. Non mutated allele in the GLA gene was methylated, compared to the non-mutated allele in the GLA gene in related patients which was not methylated resulting in more severe clinical phenotypes

challenge
unacceptableMOUSE:NEO1SMass, Team All about that base2017-04-23 13:38:04 CDTGO:0006779 porphyrin-containing compound biosynthetic process (P)PMID:28431013ECO:0000315 mutant phenotype evidence used in manual assertion

figure 7B, Table showing in vitro recombination catalysed by hepatopancreas extract and its heat inactivated form. Mouse testicular extracts acted as a positive control.

challenge
unacceptableHUMAN:APEX1SMass, Team All about that base2017-04-23 12:29:28 CDTGO:0003697 single-stranded DNA binding (F)PMID:26773055ECO:0000314 direct assay evidence used in manual assertion

in Figure 3A, histogram displaying a ChIP analysis assessing Sp1 binding to APEX1 proximal promoter. The assay was carried out using TIG-1 cells transfected with either a control siRNA, a XRCC1 siRNA or a Sp1-targeting siRNA (as positive control for signal reduction). Results are expressed as mean fold enrichment over unspecific IgG relative to control siRNA ± SD of three independent experiments.

challenge
updatedbyinstructorHUMAN:SSRP1AWynn, Team All about that base2017-04-09 17:16:29 CDTGO:1902275 regulation of chromatin organization (P)PMID:27467129ECO:0000314 direct assay evidence used in manual assertion

In Figure 3, The presence of FACT increases the efficiency of RSC-induced nucleosome mobilization.

challenge
unacceptableHUMAN:SOSB1AWynn, Team All about that base2017-04-09 16:16:01 CDTGO:0071168 protein localization to chromatin (P)PMID:26261212ECO:0000314 direct assay evidence used in manual assertion

In figure 1, hSSB1 localizes to chromatin following oxidative stress.

challenge
updatedbyinstructorMOUSE:MUTYHSMass, Team All about that base2017-04-06 14:24:00 CDTGO:0060546 negative regulation of necroptotic process (P)PMID:28059467ECO:0000315 mutant phenotype evidence used in manual assertion

In figure 2A, loss of MYH results in more TNF-alpha combined with zVAD-fmk induced cell death in primary mouse embryonic fibroblasts (MEFs).

challenge

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Pages in category "Team All about that base"

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