GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.

Have any questions? Please email us at ecoliwiki@gmail.com

MOUSE:NEO1

From GONUTS
Jump to: navigation, search
Species (Taxon ID) Mus musculus (Mouse). (10090)
Gene Name(s) Neo1 (synonyms: Ngn)
Protein Name(s) Neogenin
External Links
UniProt P97798
EMBL Y09535
UniGene Mm.42249
PDB 4BQ6
4BQ7
4BQ8
4BQ9
4BQB
4BQC
4PLN
4UI2
PDBsum 4BQ6
4BQ7
4BQ8
4BQ9
4BQB
4BQC
4PLN
4UI2
ProteinModelPortal P97798
SMR P97798
DIP DIP-32026N
IntAct P97798
MINT MINT-4997055
STRING 10090.ENSMUSP00000063656
iPTMnet P97798
PhosphoSitePlus P97798
SwissPalm P97798
MaxQB P97798
PaxDb P97798
PeptideAtlas P97798
PRIDE P97798
MGI MGI:1097159
eggNOG KOG4221
ENOG410Z913
HOGENOM HOG000230686
HOVERGEN HBG005455
InParanoid P97798
PhylomeDB P97798
Reactome [www.reactome.org/content/detail/R-MMU-373752 R-MMU-373752]
[www.reactome.org/content/detail/R-MMU-375170 R-MMU-375170]
ChiTaRS Neo1
PRO PR:P97798
Proteomes UP000000589
CleanEx MM_NEO1
GO GO:0009986
GO:0005794
GO:0005887
GO:0097708
GO:0016020
GO:0005654
GO:0005886
GO:0098797
GO:0070700
GO:0045296
GO:0039706
GO:0004872
GO:0038023
GO:0007411
GO:0007155
GO:0055072
GO:0007520
GO:0048681
GO:0050709
GO:0001764
GO:0030513
GO:0051149
GO:0048679
GO:2001222
GO:0006355
CDD cd00063
Gene3D 2.60.40.10
InterPro IPR003961
IPR007110
IPR013783
IPR013098
IPR003599
IPR003598
IPR033024
IPR010560
PANTHER PTHR10489:SF837
Pfam PF00041
PF07679
PF13895
PF06583
SMART SM00060
SM00409
SM00408
SUPFAM SSF48726
SSF49265
PROSITE PS50853
PS50835

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

enables

GO:0070700

BMP receptor binding

PMID:18326817[1]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:Q6ZVN8

F

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:2001222

regulation of neuron migration

PMID:26651291[2]

ECO:0000316

genetic interaction evidence used in manual assertion

MGI:MGI:1096335
MGI:MGI:2443718

P

occurs_in:(CL:0002609)

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:1901215

negative regulation of neuron death

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:619837

P

Seeded From UniProt

complete

part_of

GO:0098797

plasma membrane protein complex

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q92859

C

Seeded From UniProt

complete

part_of

GO:0097708

intracellular vesicle

PMID:26651291[2]

ECO:0000314

direct assay evidence used in manual assertion

C

part_of:(GO:0030426)

Seeded From UniProt

complete

GO:0006779

porphyrin-containing compound biosynthetic process

PMID:28431013[3]

ECO:0000315

P

figure 7B, Table showing in vitro recombination catalysed by hepatopancreas extract and its heat inactivated form. Mouse testicular extracts acted as a positive control.

complete
CACAO 12782

acts_upstream_of_or_within

GO:0055072

iron ion homeostasis

PMID:20065295[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:3665445

P

occurs_in:(EMAPA:16846)

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0055072

iron ion homeostasis

GO_REF:0000008

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q92859

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0050709

negative regulation of protein secretion

PMID:20065295[4]

ECO:0000314

direct assay evidence used in manual assertion

P

regulates_o_has_input:(MGI:MGI:1916835)

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0048681

negative regulation of axon regeneration

PMID:26651291[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0048679

regulation of axon regeneration

PMID:26651291[2]

ECO:0000316

genetic interaction evidence used in manual assertion

MGI:MGI:2443718

P

Seeded From UniProt

complete

enables

GO:0045296

cadherin binding

PMID:15520228[5]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0043025

neuronal cell body

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:619837

C

Seeded From UniProt

complete

enables

GO:0039706

co-receptor binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q92859

F

Seeded From UniProt

complete

enables

GO:0038023

signaling receptor activity

PMID:26651291[2]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:Q6PCX7

F

Seeded From UniProt

complete

enables

GO:0038023

signaling receptor activity

PMID:26651291[2]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:Q52KR2

F

occurs_in:(EMAPA:16894)|occurs_in:(CL:0000540)

Seeded From UniProt

complete

enables

GO:0038023

signaling receptor activity

PMID:15520228[5]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:Q9R1A3

F

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0030513

positive regulation of BMP signaling pathway

PMID:20065295[4]

ECO:0000316

genetic interaction evidence used in manual assertion

MGI:MGI:88177

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

PMID:26651291[2]

ECO:0000314

direct assay evidence used in manual assertion

C

part_of:(CL:0000540)

Seeded From UniProt

complete

part_of

GO:0009986

cell surface

PMID:26651291[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0007520

myoblast fusion

PMID:15520228[5]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0006355

regulation of transcription, DNA-templated

PMID:15520228[5]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q92859

C

Seeded From UniProt

complete

part_of

GO:0005794

Golgi apparatus

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q92859

C

Seeded From UniProt

complete

part_of

GO:0005654

nucleoplasm

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q92859

C

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0001764

neuron migration

PMID:26651291[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

occurs_in:(CL:0002609)

Seeded From UniProt

complete

part_of

GO:0005887

integral component of plasma membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR033024

C

Seeded From UniProt

complete

involved_in

GO:0007399

nervous system development

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR033024

P

Seeded From UniProt

complete

involved_in

GO:0007411

axon guidance

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR033024

P

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR010560

C

Seeded From UniProt

complete

involved_in

GO:0030513

positive regulation of BMP signaling pathway

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR033024

P

Seeded From UniProt

complete

enables

GO:0038023

signaling receptor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR033024

F

Seeded From UniProt

complete

involved_in

GO:0055072

iron ion homeostasis

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR033024

P

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

Reactome:R-MMU-593680
Reactome:R-MMU-449201
Reactome:R-MMU-421688

ECO:0000304

author statement supported by traceable reference used in manual assertion



C

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

involved_in

GO:0007155

cell adhesion

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0130

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1003
UniProtKB-SubCell:SL-0039

C

Seeded From UniProt

complete

edit table

Notes

References

See Help:References for how to manage references in GONUTS.

  1. ↑ Xia, Y et al. (2008) Hemojuvelin regulates hepcidin expression via a selective subset of BMP ligands and receptors independently of neogenin. Blood 111 5195-204 PubMed GONUTS page
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 2.8 van Erp, S et al. (2015) Lrig2 Negatively Regulates Ectodomain Shedding of Axon Guidance Receptors by ADAM Proteases. Dev. Cell 35 537-52 PubMed GONUTS page
  3. ↑ Srivastava, S et al. (2017) DNA double-strand break repair in Penaeus monodon is predominantly dependent on homologous recombination. DNA Res. 24 117-128 PubMed GONUTS page
  4. ↑ 4.0 4.1 4.2 Lee, DH et al. (2010) Neogenin inhibits HJV secretion and regulates BMP-induced hepcidin expression and iron homeostasis. Blood 115 3136-45 PubMed GONUTS page
  5. ↑ 5.0 5.1 5.2 5.3 Kang, JS et al. (2004) Netrins and neogenin promote myotube formation. J. Cell Biol. 167 493-504 PubMed GONUTS page
Retrieved from "https://gowiki.tamu.edu/wiki/index.php?title=MOUSE:NEO1&oldid=5955722"