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Category:GO:0035329 ! hippo signaling
name: hippo signaling
namespace: biological_process
def: "An intracellular signaling cascade that starts with the activation of hippo (STK4/MST1 and STK3/MST2 in mammals and hpo kinase in Drosophila). Hippo then phosphorylates LATS1/2, which in turn phosphoylates the transcriptional co-activator YAP1 (yki in Drosophila), leading to its cytosolic retention and/or degradation." [PMID:17318211, PMID:18328423, PMID:36347846]
synonym: "hippo signal transduction" EXACT [GOC:signaling]
synonym: "hippo signaling cascade" RELATED [GOC:signaling]
synonym: "hippo signaling pathway" EXACT []
synonym: "hippo signalling cascade" RELATED [GOC:mah]
synonym: "Salvador-Warts-Hippo signaling pathway" NARROW []
synonym: "SWH pathway" NARROW []
is_a: GO:0035556 ! intracellular signal transduction
AmiGO
<GOterm>GO:0035329</GOterm>
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This category has the following 2 subcategories, out of 2 total.
