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|Status||Page||Date/Time||GO Term (Aspect)||Reference||Evidence||Notes||Links|
|?||2013-02-20 13:18:16 CST||GO:0030177 positive regulation of Wnt receptor signaling pathway (As shown in the paper they are attempting to demonstrate the NEED for Porcn in the Wnt conical activity and gastrulation and germ layer establishment(Porcn required for the correct processing-acetylation- of Wnt ligands in the ER and for their extracellular distribution and gradient function) as required for the secretion of Wnt3a (isoforms of Porcn seem to be sufficient to obtain functional Wnt3a). Canonical Wnt activity assay as portrayed in Figure 2F Porcn function is dispensable in Wnt3a signal receiving cells and only required in Wnt3a secreting cells, supporting the role of Porcn in Wnt processing and secretion.)||PMID:21554866||IMP: Inferred from Mutant Phenotype||challenge|
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