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User:Surge Pres

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My Annotations

StatusPageDate/TimeGO Term (Aspect)ReferenceEvidenceNotesLinks
updatedbyinstructor?2013-02-20 13:18:16 CSTGO:0030177 positive regulation of Wnt receptor signaling pathway (As shown in the paper they are attempting to demonstrate the NEED for Porcn in the Wnt conical activity and gastrulation and germ layer establishment(Porcn required for the correct processing-acetylation- of Wnt ligands in the ER and for their extracellular distribution and gradient function) as required for the secretion of Wnt3a (isoforms of Porcn seem to be sufficient to obtain functional Wnt3a). Canonical Wnt activity assay as portrayed in Figure 2F Porcn function is dispensable in Wnt3a signal receiving cells and only required in Wnt3a secreting cells, supporting the role of Porcn in Wnt processing and secretion.)PMID:21554866IMP: Inferred from Mutant Phenotype
challenge

acceptable:0
unacceptable:0
requires_changes:0
flagged:0

Annotations challenged by Surge Pres

StatusAuthor,GroupPageGO Term (Aspect)ReferenceEvidenceLinksPage history
requireschangesAcapello,
Team Blot Blot Western Baby
PSEPK:TOLBGO:0009279 - cell outer membrane (C)PMID:10940016ECO:0000315 mutant phenotype evidence used in manual assertionchallengeC: 6
updatedbyinstructorAcapello,
Team Blot Blot Western Baby
HPV18:VE6GO:0045892 - negative regulation of transcription, DNA-templated (P)PMID:21849431ECO:0000314 direct assay evidence used in manual assertionchallengeC: 4
requireschangesAcapello,
Team Blot Blot Western Baby
NVN68:VP2GO:0043489 - RNA stabilization (P)PMID:14557646ECO:0000314 direct assay evidence used in manual assertionchallengeC: 2
updatedbyinstructorAlemus,
Team Blot Blot Western Baby
HPV16:VE2GO:0044163 - host cytoskeleton (C)PMID:15020762ECO:0000314 direct assay evidence used in manual assertionchallengeC: 2
updatedbyinstructorAlemus,
Team Blot Blot Western Baby
9HEPC:Q8V7L6GO:0052040 - modulation by symbiont of host programmed cell death (P)PMID:19951438ECO:0000314 direct assay evidence used in manual assertionchallengeC: 1
updatedbyinstructorAlemus,
Team Blot Blot Western Baby
HPV11:D7GMV3GO:0044163 - host cytoskeleton (C)PMID:15020762ECO:0000314 direct assay evidence used in manual assertionchallengeC: 4

fixed by Surge Pres
updatedbyinstructorNfarmer91,
Team Bonfire
CAEEL:TMC1GO:0005272 - sodium channel activity (F)PMID:23364694ECO:0000315 mutant phenotype evidence used in manual assertionchallengeC: 1

1 annotations fixed by Surge Pres

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