GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
HPV18:VE6
Contents
| Species (Taxon ID) | Human papillomavirus type 18. (333761) | |
| Gene Name(s) | E6 | |
| Protein Name(s) | Protein E6 | |
| External Links | ||
| UniProt | P06463 | |
| EMBL | X04354 X05015 M20325 M26798 X04773 | |
| PIR | A26165 | |
| RefSeq | NP_040310.1 | |
| PDB | 2I04 2I0I 2I0L 4JOR | |
| PDBsum | 2I04 2I0I 2I0L 4JOR | |
| ProteinModelPortal | P06463 | |
| SMR | P06463 | |
| DIP | DIP-44730N | |
| IntAct | P06463 | |
| MINT | MINT-96616 | |
| GeneID | 1489088 | |
| EvolutionaryTrace | P06463 | |
| Proteomes | UP000009109 | |
| GO | GO:0044204 GO:0003677 GO:0008270 GO:0039586 GO:0045892 GO:0039548 GO:0039574 GO:0039502 GO:0006351 | |
| InterPro | IPR001334 | |
| Pfam | PF00518 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0045892 |
negative regulation of transcription, DNA-dependent |
ECO:0000314 |
P |
Figure 5 |
complete | |||||
|
involved_in |
GO:0045892 |
negative regulation of transcription, DNA-templated |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008270 |
zinc ion binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0042025 |
host cell nucleus |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0039502 |
suppression by virus of host type I interferon-mediated signaling pathway |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000496164 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0039548 |
suppression by virus of host IRF3 activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000496164 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000496164 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006355 |
regulation of transcription, DNA-templated |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000496164 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0030165 |
PDZ domain binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000496164 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0046872 |
metal ion binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000496164 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006351 |
transcription, DNA-templated |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000496164 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0039649 |
modulation by virus of host ubiquitin-protein ligase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000496164 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0039526 |
modulation by virus of host apoptotic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0039548 |
suppression by virus of host IRF3 activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0042025 |
host cell nucleus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0030683 |
evasion or tolerance by virus of host immune response |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0046872 |
metal ion binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0016032 |
viral process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0030430 |
host cell cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0039503 |
suppression by virus of host innate immune response |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Reiser, J et al. (2011) High-risk human papillomaviruses repress constitutive kappa interferon transcription via E6 to prevent pathogen recognition receptor and antiviral-gene expression. J. Virol. 85 11372-80 PubMed GONUTS page
- ↑ Barbosa, MS et al. (1989) Papillomavirus polypeptides E6 and E7 are zinc-binding proteins. J. Virol. 63 1404-7 PubMed GONUTS page
o
s
