User:Jmcfarland

My Annotations

Status	Page	Date/Time	GO Term (Aspect)	Reference	Evidence	Notes	Links
unacceptable	MOUSE:KSYK	2013-02-10 13:18:54 CST	GO:0016310 phosphorylation (P)	PMID:7513017	ECO:0000314 direct assay evidence used in manual assertion	Figure 1-Lyn dependent phosphorylation increases autophosphorylation activity of Syk through BCR stimulation	challenge
correctedthroughchallenges	MOUSE:FGFR4	2013-02-10 14:11:45 CST	GO:0070857 regulation of bile acid biosynthetic process (P)	PMID:10809780	ECO:0000315 mutant phenotype evidence used in manual assertion	figure 2-acceleration of bile acid synthesis by blocking bile acid feedback inhibition can accelerate gallbladder emptying and a decrease in gallbladder volume.	challenge
unacceptable	MOUSE:FGFR4	2013-02-10 15:10:18 CST	GO:0016301 kinase activity (F)	PMID:14739300	ECO:0000315 mutant phenotype evidence used in manual assertion	figure 3- the results suggest that the presence of kinase activity of Src is necessary for actin ring formation and bone resorption	challenge
correctedthroughchallenges	MOUSE:EFNA1	2013-02-10 15:51:09 CST	GO:0048013 ephrin receptor signaling pathway (P)	PMID:16782872	ECO:0000314 direct assay evidence used in manual assertion	Figure 3-results indicate that both Vav2 and Vav3 are activated by EphA receptor forward signaling to promote Rac1 GTPase activity.	challenge
unacceptable	MOUSE:FGL2	2013-02-10 16:50:39 CST	GO:0002836 positive regulation of response to tumor cell (P)	PMID:18932275	ECO:0000314 direct assay evidence used in manual assertion	table 2- cells displayed increased expression of fgl2 protein in tumor tissues of the patients	challenge

acceptable:0
unacceptable:3
requires_changes:0
flagged:0

Annotations challenged by Jmcfarland

Status	Author,Group	Page	GO Term (Aspect)	Reference	Evidence	Links	Page history
updatedbyinstructor	Lallison2012, Team Bonfire	MOUSE:GDF8	GO:0033673 - negative regulation of kinase activity (P)	PMID:19357233	ECO:0000315 mutant phenotype evidence used in manual assertion	challenge	C: 3
unacceptable	Vthompsonui, Team Buster McThunderstick	MOUSE:SMAD1	GO:0030509 - BMP signaling pathway (P)	PMID:11788714	ECO:0000314 direct assay evidence used in manual assertion	challenge	C: 1
updatedbyinstructor	Shall, Team Robots In Disguise	RAT:MINK1	GO:0070050 - neuron cellular homeostasis (P)	PMID:21048137	ECO:0000315 mutant phenotype evidence used in manual assertion	challenge	C: 5

0 annotations fixed by Jmcfarland

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