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User:Shall

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My Annotations

StatusPageDate/TimeGO Term (Aspect)ReferenceEvidenceNotesLinks
unacceptableRABVS:PHOSP2013-02-05 12:18:26 CSTGO:0019083 viral transcription (P)PMID:15557246ECO:0000314 direct assay evidence used in manual assertion

Figure 3 shows a western blott which shows that N and P were detected in fractions 11–15 and again in fractions 17–18 which indicates that most of N formed complexes with P which inhibits the binding of N to RNA

challenge
updatedbyinstructorRAT:MINK12013-02-08 01:16:11 CSTGO:0070050 neuron homeostasis (P)PMID:21048137ECO:0000315 mutant phenotype evidence used in manual assertion

In figure 2 the effects of MINK and TNIK knockdown on neuronal morphology were visualized by co-transfected DsRed.Both MINK-RNAi and TNIK-RNAi significantly reduced arbor complexity relative to control neurons

challenge
updatedbyinstructorRAT:D3ZZQ02013-02-08 01:32:25 CSTGO:0050775 positive regulation of dendrite morphogenesis (P)PMID:21048137ECO:0000315 mutant phenotype evidence used in manual assertion

In Figure 2 The effects of MINK and TNIK knockdown on neuronal morphology were visualized by co-transfected DsRed. Both MINK-RNAi and TNIK-RNAi significantly reduced arbor complexity relative to control neurons

challenge
updatedbyinstructorHUMAN:MINK12013-02-08 09:59:45 CSTGO:0006468 protein phosphorylation (P)PMID:21690388ECO:0000315 mutant phenotype evidence used in manual assertion

In figure 4A shows a western blot which shows that after OA treatment, cells with Msn overexpression exhibited higher levels of T312 phosphorylation

challenge
requireschangesHUMAN:M3K12013-02-08 10:19:06 CSTGO:0004672 protein kinase activity (F)PMID:21129722ECO:0000314 direct assay evidence used in manual assertion

In figures 4A the effects MAP3K1 mutations on phosphorylation of downstream targets were examined by quantitative immunoblot analysis. Levels of phospho-ERK were increased in all the mutant cell lines in comparison to wild-type

challenge

acceptable:0
unacceptable:1
requires_changes:1
flagged:0

Annotations challenged by Shall

StatusAuthor,GroupPageGO Term (Aspect)ReferenceEvidenceLinksPage history
correctedthroughchallengesSbutler,
Team Thundercats Ho!
HUMAN:KSYKGO:0006468 - protein phosphorylation (P)PMID:18818202ECO:0000314 direct assay evidence used in manual assertionchallengeC: 4

fixed by Cwolterman
updatedbyinstructorKpatel,
Team Llamarmy
DANRE:Q7ZU02GO:0008283 - cell population proliferation (P)PMID:22782722ECO:0000315 mutant phenotype evidence used in manual assertionchallengeC: 3

fixed by Cwolterman
updatedbyinstructorDylandekalb,
Team Higgs BROsons
HUMAN:TMIG2GO:0045766 - positive regulation of angiogenesis (P)PMID:22419821ECO:0000315 mutant phenotype evidence used in manual assertionchallengeC: 3

fixed by Kathrynmartin
updatedbyinstructorKthornhill,
Team Genetic Ninjas
MOUSE:PLCZ1GO:0004435 - phosphatidylinositol phospholipase C activity (F)PMID:14701816ECO:0000314 direct assay evidence used in manual assertionchallengeC: 4

0 annotations fixed by Shall

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