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RABVS:PHOSP

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Species (Taxon ID) Rabies virus (strain SAD B19) (RABV). (11300)
Gene Name(s) P
Protein Name(s) Phosphoprotein

Protein P Protein M1

External Links
UniProt P16286
EMBL M31046
AF499686
EF206708
EF206709
EF206710
EF206711
EF206712
EF206713
EF206714
EF206715
EF206716
EF206719
EF206720
PIR B34746
ProteinModelPortal P16286
SMR P16286
Proteomes UP000006363
UP000007308
GO GO:0030430
GO:0042025
GO:0019012
GO:0003968
GO:0075521
GO:0039563
GO:0039564
GO:0039502
GO:0046718
GO:0019083
InterPro IPR004259
Pfam PF03012
ProDom PD004155

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0019083

viral transcription

PMID:15557246[1]

ECO:0000314

P

Figure 3 shows a western blott which shows that N and P were detected in fractions 11–15 and again in fractions 17–18 which indicates that most of N formed complexes with P which inhibits the binding of N to RNA

complete
CACAO 6351

GO:0039653

suppression by virus of host transcription

PMID:15919920[2]

ECO:0000315

P

Figure 3. Rabies P protein suppresses host transcription of IFN-beta.

complete
CACAO 8681

GO:0039653

suppression by virus of host transcription

PMID:15919920[2]

ECO:0000315

P

Figure 6. Expression of P is sufficient to prevent TBK-1-mediated IFN-β induction.

complete
CACAO 9072

involved_in

GO:0039653

suppression by virus of host transcription

PMID:15919920[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0001172

transcription, RNA-templated

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0003968

P

Seeded From UniProt

complete

enables

GO:0003968

RNA-directed 5'-3' RNA polymerase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004259
InterPro:IPR037199

F

Seeded From UniProt

complete

involved_in

GO:0019083

viral transcription

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004259
InterPro:IPR037199

P

Seeded From UniProt

complete

part_of

GO:0042025

host cell nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1048
UniProtKB-SubCell:SL-0414

C

Seeded From UniProt

complete

involved_in

GO:0039563

suppression by virus of host STAT1 activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1105

P

Seeded From UniProt

complete

involved_in

GO:0030683

evasion or tolerance by virus of host immune response

GO_REF:0000037
GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0899
UniProtKB-KW:KW-0922

P

Seeded From UniProt

complete

involved_in

GO:0039564

suppression by virus of host STAT2 activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1106

P

Seeded From UniProt

complete

part_of

GO:0019012

virion

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0946
UniProtKB-SubCell:SL-0274

C

Seeded From UniProt

complete

part_of

GO:0030430

host cell cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1035
UniProtKB-SubCell:SL-0381

C

Seeded From UniProt

complete

involved_in

GO:0016032

viral process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0945

P

Seeded From UniProt

complete

involved_in

GO:0075521

microtubule-dependent intracellular transport of viral material towards nucleus

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1177

P

Seeded From UniProt

complete

involved_in

GO:0039502

suppression by virus of host type I interferon-mediated signaling pathway

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1114

P

Seeded From UniProt

complete

involved_in

GO:0046718

viral entry into host cell

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1160

P

Seeded From UniProt

complete

involved_in

GO:0075606

transport of viral material towards nucleus

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1176

P

Seeded From UniProt

complete

involved_in

GO:0039503

suppression by virus of host innate immune response

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1090

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Liu, P et al. (2004) Interactions amongst rabies virus nucleoprotein, phosphoprotein and genomic RNA in virus-infected and transfected cells. J. Gen. Virol. 85 3725-34 PubMed GONUTS page
  2. 2.0 2.1 2.2 Brzózka, K et al. (2005) Identification of the rabies virus alpha/beta interferon antagonist: phosphoprotein P interferes with phosphorylation of interferon regulatory factor 3. J. Virol. 79 7673-81 PubMed GONUTS page