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HUMAN:TMIG2
Contents
| Species (Taxon ID) | Homo sapiens (Human). (9606) | |
| Gene Name(s) | TMIGD2 (synonyms: CD28H, IGPR1) | |
| Protein Name(s) | Transmembrane and immunoglobulin domain-containing protein 2
CD28 homolog Immunoglobulin and proline-rich receptor 1 IGPR-1 | |
| External Links | ||
| UniProt | Q96BF3 | |
| EMBL | AY358964 BC015655 | |
| CCDS | CCDS12126.1 CCDS59334.1 | |
| RefSeq | NP_001162597.1 NP_653216.2 | |
| UniGene | Hs.263928 | |
| ProteinModelPortal | Q96BF3 | |
| SMR | Q96BF3 | |
| BioGrid | 125971 | |
| PhosphoSite | Q96BF3 | |
| DMDM | 125991218 | |
| PaxDb | Q96BF3 | |
| PRIDE | Q96BF3 | |
| Ensembl | ENST00000301272 ENST00000595645 | |
| GeneID | 126259 | |
| KEGG | hsa:126259 | |
| UCSC | uc002lzx.2 uc010dtv.2 | |
| CTD | 126259 | |
| GeneCards | GC19M004292 | |
| H-InvDB | HIX0014660 | |
| HGNC | HGNC:28324 | |
| HPA | HPA011081 | |
| MIM | 614715 | |
| neXtProt | NX_Q96BF3 | |
| PharmGKB | PA145148047 | |
| eggNOG | NOG85375 | |
| GeneTree | ENSGT00390000007100 | |
| HOGENOM | HOG000154641 | |
| InParanoid | Q96BF3 | |
| KO | K16668 | |
| OMA | YSNVLYR | |
| OrthoDB | EOG7VB2G7 | |
| PhylomeDB | Q96BF3 | |
| TreeFam | TF341425 | |
| GenomeRNAi | 126259 | |
| NextBio | 81741 | |
| PRO | PR:Q96BF3 | |
| Proteomes | UP000005640 | |
| Bgee | Q96BF3 | |
| CleanEx | HS_TMIGD2 | |
| Genevestigator | Q96BF3 | |
| GO | GO:0016021 GO:0005886 GO:0015026 GO:0042104 GO:0001819 GO:0007165 GO:0031295 | |
| Gene3D | 2.60.40.10 | |
| InterPro | IPR007110 IPR013783 IPR003599 | |
| SMART | SM00409 | |
| PROSITE | PS50835 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0045766 |
positive regulation of angiogenesis |
ECO:0000315 |
P |
Figure 3- "IGPR-1 activity regulates angiogenesis in vivo and in vitro" |
complete | |||||
|
involved_in |
GO:0045766 |
positive regulation of angiogenesis |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0042104 |
positive regulation of activated T cell proliferation |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0031295 |
T cell costimulation |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0015026 |
coreceptor activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0001819 |
positive regulation of cytokine production |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006955 |
immune response |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:98936 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005615 |
extracellular space |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000587099 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0002377 |
immunoglobulin production |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:98936 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Rahimi, N et al. (2012) Identification of IGPR-1 as a novel adhesion molecule involved in angiogenesis. Mol. Biol. Cell 23 1646-56 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 Zhu, Y et al. (2013) B7-H5 costimulates human T cells via CD28H. Nat Commun 4 2043 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
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