User:Ayusol

My Annotations

Status	Page	Date/Time	GO Term (Aspect)	Reference	Evidence	Notes	Links
correctedthroughchallenges	9FLAV:A0MNX0	2013-02-10 00:22:52 CST	GO:0036338 viral membrane (C)	PMID:23300717	ECO:0000314 direct assay evidence used in manual assertion	Figure 1: Confirms the relationship between Protein E and prM. Protein E's function is an envelope protein and helps in protecting.This is also proven in Figure E.	challenge
unacceptable	HUMAN:TRBM	2013-02-10 08:04:26 CST	GO:0030195 negative regulation of blood coagulation (P)	PMID:23383040	ECO:0000269 experimental evidence used in manual assertion	Figure 1: MIF, sTM and PC concentrations are increased in plasma of patients with DHF cited from PMID:23383040. Thrombomodulin induces the activation of Protein C which is not very helpful for a person infected with DHF. It can be very harmful.	challenge
acceptable	HUMAN:IFM1	2013-02-10 17:17:21 CST	GO:0046597 negative regulation of viral entry into host cell (P)	PMID:23358889	ECO:0000314 direct assay evidence used in manual assertion	Figure 1 IFITM proteins differentially restrict JSRV, 10A1 MLV, IAV and VSV entry and Figure 4 Cell-cell fusion induced by JSRV Env is inhibited by IFITM proteins, and extracellular low pH pulse cannot overcome IFITM1-mediated restriction on JSRV entry clearly show that IFITM1 is acting as a defense by redistricting the virus from entering the host.	challenge
unacceptable	PIG:ITIH4	2013-02-10 17:40:17 CST	GO:0006953 acute-phase response (P)	PMID:23332090	ECO:0000269 experimental evidence used in manual assertion	Figures 1, 3, and 6 verify that we can indeed coin out infected pigs from uninfected pigs.	challenge
acceptable	HHV1F:GB	2013-02-21 15:46:23 CST	GO:0019031 viral envelope (C)	PMID:23382920	ECO:0000314 direct assay evidence used in manual assertion	Figure 1: Soluble gB is a biologically active form of the glycoprotein; present in the virus envelope.Figure 3 HSV-1-encoded gB stimulates NF-κB activity through TLR2 that does not require CD14. Showing the importance of protein as a PAMP.	challenge
updatedbyinstructor	WNV:POLG	2013-02-21 16:03:46 CST	GO:0045070 positive regulation of viral genome replication (P)	PMID:22553322	ECO:0000315 mutant phenotype evidence used in manual assertion	Figure 3 and figure 4 for NS4B, but the expt was done in the presence of NS4 F86C mutation, but UniProt doesn't offer separate mature protein record for each component of the polyprotein from WNV.	challenge
updatedbyinstructor	DEN4T:POLG	2013-02-21 20:10:49 CST	GO:0030683 evasion or tolerance by virus of host immune response (P)	PMID:23300717	ECO:0000315 mutant phenotype evidence used in manual assertion	Fig 6 & 7	challenge
updatedbyinstructor	9FLAV:C7AG48	2013-02-21 20:47:10 CST	GO:0046774 suppression by virus of host intracellular interferon activity (P)	PMID:16731929	ECO:0000314 direct assay evidence used in manual assertion	FIG. 4	challenge

acceptable:2
unacceptable:2
requires_changes:0
flagged:0

Annotations challenged by Ayusol

Status	Author,Group	Page	GO Term (Aspect)	Reference	Evidence	Links	Page history
updatedbyinstructor	Sbutler, Team Thundercats Ho!	HUMAN:KSYK	GO:0045579 - positive regulation of B cell differentiation (P)	PMID:18369315	ECO:0000315 mutant phenotype evidence used in manual assertion	challenge	C: 5
acceptable	Sbutler, Team Thundercats Ho!	HUMAN:KSYK	GO:0004672 - protein kinase activity (F)	PMID:18818202	ECO:0000314 direct assay evidence used in manual assertion	challenge	C: 1
updatedbyinstructor	ML, Team JCML	MOUSE:FZD5	GO:0031077 - post-embryonic camera-type eye development (P)	PMID:18832390	ECO:0000315 mutant phenotype evidence used in manual assertion	challenge	C: 3
updatedbyinstructor	Mcravens, Team Racer X	CALRH:SLYA	GO:0060300 - regulation of cytokine activity (P)	PMID:20738764	ECO:0000314 direct assay evidence used in manual assertion	challenge	C: 1 fixed by Ayusol

1 annotations fixed by Ayusol

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