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HHV1F:GB
Contents
| Species (Taxon ID) | Human herpesvirus 1 (strain F) (HHV-1) (Human herpes simplex virus 1). (10304) | |
| Gene Name(s) | gB | |
| Protein Name(s) | Envelope glycoprotein B
gB gB-1 gB1 | |
| External Links | ||
| UniProt | P06436 | |
| EMBL | M14164 M21633 | |
| PIR | A03750 | |
| PDB | 1RJY 1RJZ 1RK0 1RK1 1T0M 1T0N | |
| PDBsum | 1RJY 1RJZ 1RK0 1RK1 1T0M 1T0N | |
| ProteinModelPortal | P06436 | |
| SMR | P06436 | |
| IntAct | P06436 | |
| EvolutionaryTrace | P06436 | |
| GO | GO:0044175 GO:0044178 GO:0020002 GO:0016021 GO:0019031 GO:0055036 GO:0046718 GO:0019062 | |
| InterPro | IPR000234 | |
| Pfam | PF00606 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0055036 |
virion membrane |
PMID:PMC255182 |
ECO:0000314 |
C |
The gB-1 polypeptide is protected from proteolysis by the membrane of the virion. This is due, in part, to a short COOH-terminal cytoplasmic tail that can be observed in figure 7. The discussion located below figure 7 discusses this characteristic in further detail. |
complete | ||||
| GO:0019031 |
viral envelope |
ECO:0000314 |
C |
Figure 1: Soluble gB is a biologically active form of the glycoprotein; present in the virus envelope.Figure 3 HSV-1-encoded gB stimulates NF-κB activity through TLR2 that does not require CD14. Showing the importance of protein as a PAMP. |
complete | |||||
|
part_of |
GO:0019031 |
viral envelope |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0019031 |
viral envelope |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000335160 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0019062 |
virion attachment to host cell |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000335160 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0044178 |
host cell Golgi membrane |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000335160 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0055036 |
virion membrane |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000335160 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0020002 |
host cell plasma membrane |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000335160 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000335160 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0044175 |
host cell endosome membrane |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000335160 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0046718 |
viral entry into host cell |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000335160 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0046718 |
viral entry into host cell |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0033644 |
host cell membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0020002 |
host cell plasma membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0019012 |
virion |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0044174 |
host cell endosome |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0019031 |
viral envelope |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0019062 |
virion attachment to host cell |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0044177 |
host cell Golgi apparatus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0016032 |
viral process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0055036 |
virion membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0044178 |
host cell Golgi membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0044175 |
host cell endosome membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Cai, M et al. (2013) The herpes simplex virus 1-encoded envelope glycoprotein B activates NF-κB through the Toll-like receptor 2 and MyD88/TRAF6-dependent signaling pathway. PLoS ONE 8 e54586 PubMed GONUTS page
