PIG:ITIH4

Species (Taxon ID)	Sus scrofa (Pig). (9823)
Gene Name(s)	ITIH4 (synonyms: IHRP)
Protein Name(s)	Inter-alpha-trypsin inhibitor heavy chain H4 ITI heavy chain H4 ITI-HC4 Inter-alpha-inhibitor heavy chain 4 Inter-alpha-trypsin inhibitor family heavy chain-related protein IHRP Major acute phase protein MAP
External Links
UniProt	P79263
EMBL	U43164 S82800 M29507
PIR	JC4625
RefSeq	NP_001001537.1
UniGene	Ssc.50918
ProteinModelPortal	P79263
STRING	9823.ENSSSCP00000012206
PaxDb	P79263
PRIDE	P79263
GeneID	396799
KEGG	ssc:396799
CTD	3700
eggNOG	COG2304
HOGENOM	HOG000000680
HOVERGEN	HBG057734
InParanoid	P79263
Proteomes	UP000008227
GO	GO:0005576 GO:0004867 GO:0006953 GO:0030212 GO:0034097
Gene3D	3.40.50.410
InterPro	IPR010600 IPR013694 IPR002035
Pfam	PF06668 PF08487 PF00092
SMART	SM00609 SM00327
SUPFAM	SSF53300
PROSITE	PS51468 PS50234

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0006953	acute-phase response	PMID:23332090	ECO:0000269			P		Figures 1, 3, and 6 verify that we can indeed coin out infected pigs from uninfected pigs.	complete CACAO 6589
involved_in	GO:0034097	response to cytokine	PMID:10712621	ECO:0000270	expression pattern evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0006953	acute-phase response	PMID:10712621	ECO:0000270	expression pattern evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0010951	negative regulation of endopeptidase activity	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0004867	P		Seeded From UniProt	complete
involved_in	GO:0010951	negative regulation of endopeptidase activity	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0004867	P		Seeded From UniProt	complete
enables	GO:0004867	serine-type endopeptidase inhibitor activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR010600	F		Seeded From UniProt	complete
involved_in	GO:0030212	hyaluronan metabolic process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR010600	P		Seeded From UniProt	complete
enables	GO:0004867	serine-type endopeptidase inhibitor activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0722	F		Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0964 UniProtKB-SubCell:SL-0243	C		Seeded From UniProt	complete
involved_in	GO:0006953	acute-phase response	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0011	P		Seeded From UniProt	complete
involved_in	GO:0010466	negative regulation of peptidase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0646	P		Seeded From UniProt	complete
enables	GO:0030414	peptidase inhibitor activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0646	F		Seeded From UniProt	complete
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References

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