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CALRH:SLYA

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Species (Taxon ID) Calloselasma rhodostoma (Malayan pit viper) (Agkistrodon rhodostoma). (8717)
Gene Name(s) No Information Provided.
Protein Name(s) Snaclec rhodocytin subunit alpha

Aggretin alpha chain Rhodoaggretin subunit alpha

External Links
UniProt Q9I841
EMBL AF244900
PIR PC7027
PDB 2VRP
3BX4
3WWK
PDBsum 2VRP
3BX4
3WWK
ProteinModelPortal Q9I841
SMR Q9I841
DIP DIP-61334N
HOVERGEN HBG004151
EvolutionaryTrace Q9I841
GO GO:0005576
GO:0046872
GO:0060300
Gene3D 3.10.100.10
InterPro IPR001304
IPR016186
IPR018378
IPR016187
Pfam PF00059
SMART SM00034
SUPFAM SSF56436
PROSITE PS00615
PS50041

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0060300

regulation of cytokine activity

PMID:20738764[1]

ECO:0000314

P

Results obtained from ELISA. The positive correlation between aggretin introduction and cytokine release by phagocytes is demonstrated in Fig 3.

complete
CACAO 6551

involved_in

GO:0060300

regulation of cytokine activity

PMID:20738764[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0009405

pathogenesis

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0090729

P

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0964
UniProtKB-SubCell:SL-0243

C

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

enables

GO:0090729

toxin activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0800

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Chang, CH et al. (2010) A novel mechanism of cytokine release in phagocytes induced by aggretin, a snake venom C-type lectin protein, through CLEC-2 ligation. J. Thromb. Haemost. 8 2563-70 PubMed GONUTS page