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Category:GO:0043111 ! replication fork arrest
name: replication fork arrest
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of DNA replication by impeding the progress of the DNA replication fork. Replication fork arrest is one of the 'quality control' processes ensuring that DNA-dependent DNA replication occurs correctly. DNA replication fork arrest during DNA-dependent DNA replication is not known to occur outside of cases where a replication error needs to be prevented or corrected." [GOC:jl, GOC:pr, PMID:14645529]
comment: See also the biological process term 'site-specific replication termination ; GO:0071170' and its children.
synonym: "negative regulation of DNA replication at replication fork barrier" EXACT [GOC:dph, GOC:tb]
synonym: "replication fork blocking" EXACT []
synonym: "replication fork stalling" EXACT []
is_a: GO:0045005 ! DNA-templated DNA replication maintenance of fidelity
is_a: GO:2000104 ! negative regulation of DNA-templated DNA replication
AmiGO
<GOterm>GO:0043111</GOterm>
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This category has the following 4 subcategories, out of 4 total.
