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Category talk:CACAO Fall 2016

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GO Term (GitHub) Requests

Ask us for help if this is your first Term Request. You'll need to read through this NTR Guide as well. Making an entry here only reminds us you have made a term request on the proper page, this table is not where the GO Consortium will address your requests. You must do that on GitHub.

If you do not yet have a GitHub ticket for your request, you should not edit this table.

User Type GO ID term name GitHub Link GONUTS Link Status Notes

User:EClary

Fixed Definition

GO:0031297

replication fork processing

https://github.com/geneontology/go-ontology/issues/12682#issuecomment-250118194

accepted by GOC

When I look on QuickGO and AmiGO, the definition for the termGO:0031297 (replication fork processing) is "The process in which a DNA replication fork that has stalled is to a functional state and replication is restarted..." I believe that there is an error in this definition and it should read "The process in which a DNA replication fork that has stalled is RESTORED to a functional state and replication is restarted..."

User:CSears

New term request

https://github.com/geneontology/go-ontology/issues/12710

accepted by GOC

Name: Regulation of Golgi lumen acidification Definition: Any process that modulates the frequency, rate, or extent of a process that reduces the internal pH of the Golgi lumen. Aspect: cellular process Relationships: Parent term -GO:0032847 regulation of cellular pH reductions; sibling term toGO:1901546 regulation of synaptic vesicle lumen acidification Reference: PMID:23447592[1], particularly figure 5

[[User:yourusername]]

Please select one

Link to the GitHub ticket where the request was made

Link to the annotation. Format as [[Special:Cacao/annotation/10937]]: Special:Cacao/annotation/10937

Please select one

Provide your suggested GO term name, etc.

User:CSears

New term request

https://github.com/geneontology/go-ontology/issues/12710

accepted by GOC

Name: negative regulation of Golgi lumen acidification Definition: Any process that stops, prevents or reduces the frequency, rate or extent of Golgi lumen acidification.

User:CSears

New term request

https://github.com/geneontology/go-ontology/issues/12710

accepted by GOC

Name: positive regulation of Golgi lumen acidification Definition: Any process that activates or increases the frequency, rate or extent of Golgi lumen acidification.

User:CSears

New term request

GO:0061795

https://github.com/geneontology/go-ontology/issues/12710

accepted by GOC

Name: Golgi lumen acidification Definition: Any process that reduces the pH of the Golgi lumen, measured by the concentration of the hydrogen ion.

EClary

Fixed Definition

GO:0043111

replication fork arrest

https://github.com/geneontology/go-ontology/issues/12749

accepted by GOC

I was unsure thatGO:0043111 (replication fork arrest), always related to its parent termGO:0045005 (DNA-dependent DNA replication maintenance of fidelity), so I proposed that the relationship between these two terms be modified. This resulted in the modification of the definition ofGO:0043111 (replication fork arrest). The definition was changed to "Any process that stops, prevents, or reduces the frequency, rate or extent of DNA replication by impeding the progress of the DNA replication fork. Replication fork arrest is one of the 'quality control' processes ensuring that DNA-dependent DNA replication occurs correctly. DNA replication fork arrest during DNA-dependent DNA replication is not known to occur outside of cases where a replication error needs to be prevented or corrected."

EClary

Fixed Definition

GO:0008753

NADPH dehydrogenase (quinone) activity

https://github.com/geneontology/go-ontology/issues/12750

requested

EClary

Fixed Definition

GO:0003959

NADPH dehydrogenase activity

https://github.com/geneontology/go-ontology/issues/12750

requested

User:PGiovanelli

New term request

GO:1905703

https://github.com/geneontology/go-ontology/issues/12798

accepted by GOC

Neg. Reg. Inhibitory synapse assembly

http://www.ebi.ac.uk/QuickGO/GTerm?id=GO:1904862#term=info

ID:GO:1905702 Label: regulation of inhibitory synapse assembly ID:GO:1905703 Label: negative regulation of inhibitory synapse assembly ID:GO:1905704 Label: positive regulation of inhibitory synapse assembly

User:PGiovanelli

New term request

GO:1905704

https://github.com/geneontology/go-ontology/issues/12798

accepted by GOC

http://www.ebi.ac.uk/QuickGO/GTerm?id=GO:1904862#term=info

Pos. Reg.GO:1905704 Label: positive regulation of inhibitory synapse assembly


User:PGiovanelli

New term request

GO:1905702

https://github.com/geneontology/go-ontology/issues/12798

accepted by GOC

Neg. Reg. Inhibitory synapse assembly

http://www.ebi.ac.uk/QuickGO/GTerm?id=GO:1904862#term=info

ID:GO:1905702 Label: regulation of inhibitory synapse assembly

User:PGiovanelli

New term request

regulation of inhibitory synapse assembly

https://github.com/geneontology/go-ontology/issues/12799

accepted by GOC

NTR: Regulation of synapse disassembly

... this is still being resolved.

  1. Condon, KH et al. (2013) The Angelman syndrome protein Ube3a/E6AP is required for Golgi acidification and surface protein sialylation. J. Neurosci. 33 3799-814 PubMed GONUTS page