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User:Zielin64

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CACAO Spring 2014

My Annotations

StatusPageDate/TimeGO Term (Aspect)ReferenceEvidenceNotesLinks
unacceptableYEAST:URA72014-04-04 13:16:23 CDTGO:0008654 phospholipid biosynthetic process (P)PMID:18439916ECO:0000314 direct assay evidence used in manual assertion

Figure 2 shows the pathway of phospholipid synthesis that CTP synthetase plays a role in.

challenge
updatedbyinstructorHUMAN:GPX72014-04-04 15:38:04 CDTGO:0004096 catalase activity (F)PMID:22157330ECO:0000314 direct assay evidence used in manual assertion

Figure 1B shows an inverse relationship between levels of GPX7 and H202 and its oxidative neutralizing ability.

challenge
unacceptableHUMAN:GPX72014-04-04 16:19:20 CDTGO:0055114 oxidation-reduction process (P)PMID:22157330ECO:0000314 direct assay evidence used in manual assertion

Figure 3A shows how GPX7 decreases levels of H202 in epithelial cells exposed to pH 4 bile acids.

challenge
updatedbyinstructorPLAF4:KC12014-04-05 17:41:04 CDTGO:0004674 protein serine/threonine kinase activity (F)PMID:24658579ECO:0000314 direct assay evidence used in manual assertion

Figure 1 shows the phosphorylation activity of Ser13 and Tyr16 in vitro by caesin kinase protein.

challenge
acceptableHUMAN:CD1512014-04-06 14:15:58 CDTGO:0005604 basement membrane (C)PMID:23302890ECO:0000314 direct assay evidence used in manual assertion

Figure 1 shows the distribution of CD151 in the basement membrane of human cervical mucosa through staining.

challenge

acceptable:1
unacceptable:2
requires_changes:0
flagged:0

Annotations challenged by Zielin64

StatusAuthor,GroupPageGO Term (Aspect)ReferenceEvidenceLinksPage history
unacceptableJohn.p.schmidt,
The A Team
STRVR:Q9RIL1GO:0010468 - regulation of gene expression (P)PMID:24498397ECO:0000315 mutant phenotype evidence used in manual assertionchallengeC: 2
updatedbyinstructorTnguyen2,
Team Food Rewards
?GO:0043032 - positive regulation of macrophage activation (Figure 6C: Analysis of RT-PCR showed that enforced expression of Ifi204 favors M-CSF-dependent macrophage differentiation in in FD-Fms cells.)PMID:16244109IDA: Inferred from Direct Assay challengeC: 2

fixed by Zielin64
updatedbyinstructorAlberthi,
MichSt14A 25
XANCB:B0RSR5GO:0003994 - aconitate hydratase activity (F)PMID:9663682ECO:0000315 mutant phenotype evidence used in manual assertionchallengeC: 2

fixed by Alberthi

1 annotations fixed by Zielin64

What do the icons mean in the status column?

assessment icons.jpg