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User:Schlagelc

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My Annotations

StatusPageDate/TimeGO Term (Aspect)ReferenceEvidenceNotesLinks
acceptableEBORR:NCAP2013-02-09 16:56:33 CSTGO:0019013 viral nucleocapsid (C)PMID:23062147ECO:0000314 direct assay evidence used in manual assertion

Fig 1 shows presence of protein

challenge
acceptableEBOZM:NCAP2013-02-09 17:11:23 CSTGO:0019013 viral nucleocapsid (C)PMID:23062147ECO:0000314 direct assay evidence used in manual assertion

Fig 1 shows concentration of protein. Reference to GenBank L11365 references Mayinga 1976 strain.

challenge
acceptableBPV1:VE72013-02-10 17:03:43 CSTGO:0019087 transformation of host cell by virus (P)PMID:11119620ECO:0000314 direct assay evidence used in manual assertion

Evidenced through western blot, shown in figure 1

challenge
acceptableBPV1:VE52013-02-10 17:40:00 CSTGO:0019087 transformation of host cell by virus (P)PMID:11119620ECO:0000314 direct assay evidence used in manual assertion

Figure 6 shows co-transforming actions of both E7, E6, and E5

challenge
updatedbyinstructorSENDZ:V2013-02-23 13:56:43 CSTGO:0039503 suppression by virus of host innate immune response (P)PMID:22532687ECO:0000315 mutant phenotype evidence used in manual assertion

Table 1 reveals the decreased prevelance of virus in mice infected with virus lacking the V protein gene. Background information supports the connection of V protein to suppression of immune response.

challenge
requireschanges9PARA:I7BT832013-02-23 14:48:47 CSTGO:0039565 suppression by virus of host STAT1 activity by positive regulation of STAT1 catabolic process (P)PMID:22090137ECO:0000315 mutant phenotype evidence used in manual assertion

Fig 7

challenge
updatedbyinstructorPIV5:V2013-02-24 15:08:17 CSTGO:0039554 suppression by virus of host MDA-5 activity (P)PMID:15563593ECO:0000314 direct assay evidence used in manual assertion

Fig 3 & 4.

challenge
updatedbyinstructor9PARA:F8V2V12013-02-24 15:19:53 CSTGO:0039554 suppression by virus of host MDA-5 activity (P)PMID:15563593ECO:0000314 direct assay evidence used in manual assertion

Fig 5

challenge

acceptable:4
unacceptable:0
requires_changes:1
flagged:0

Annotations challenged by Schlagelc

StatusAuthor,GroupPageGO Term (Aspect)ReferenceEvidenceLinksPage history
updatedbyinstructorSwhipple,
Team Breakfast Taco
EBOZM:VP24GO:0020002 - host cell plasma membrane (C)PMID:12525613ECO:0000314 direct assay evidence used in manual assertionchallengeC: 3

fixed by Lfileccia
updatedbyinstructorSwhipple,
Team Breakfast Taco
EBOZM:VP40GO:0045121 - membrane raft (C)PMID:14673115ECO:0000314 direct assay evidence used in manual assertionchallengeC: 2
updatedbyinstructorSwhipple,
Team Breakfast Taco
EBOZM:VGPGO:0045121 - membrane raft (C)PMID:11877482ECO:0000314 direct assay evidence used in manual assertionchallengeC: 3

fixed by Lfileccia

0 annotations fixed by Schlagelc

What do the icons mean in the status column?

assessment icons.jpg