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PIV5:V
Contents
Species (Taxon ID) | Parainfluenza virus 5 (strain W3) (PIV5) (Simian virus 5). (11208) | |
Gene Name(s) | P/V | |
Protein Name(s) | Non-structural protein V | |
External Links | ||
UniProt | P11207 | |
EMBL | J03142 AF052755 | |
PIR | A31594 | |
RefSeq | YP_138513.1 | |
PDB | 2B5L 2HYE 2K48 4I1S | |
PDBsum | 2B5L 2HYE 2K48 4I1S | |
ProteinModelPortal | P11207 | |
SMR | P11207 | |
DIP | DIP-48759N | |
IntAct | P11207 | |
MINT | MINT-6623137 | |
GeneID | 3160800 | |
EvolutionaryTrace | P11207 | |
Proteomes | UP000007232 | |
GO | GO:0030430 GO:0046872 GO:0003723 GO:0039554 GO:0039563 GO:0039502 | |
InterPro | IPR024279 IPR025909 | |
Pfam | PF14313 PF13008 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
GO:0039554 |
suppression by virus of host MDA-5 activity |
ECO:0000314 |
P |
Fig 3 & 4. |
complete | |||||
involved_in |
GO:0039554 |
suppression by virus of host MDA-5 activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0046872 |
metal ion binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0039554 |
suppression by virus of host MDA-5 activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0003723 |
RNA binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0046872 |
metal ion binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0039503 |
suppression by virus of host innate immune response |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0030430 |
host cell cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0016032 |
viral process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0030683 |
evasion or tolerance by virus of host immune response |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0039502 |
suppression by virus of host type I interferon-mediated signaling pathway |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0039563 |
suppression by virus of host STAT1 activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Andrejeva, J et al. (2004) The V proteins of paramyxoviruses bind the IFN-inducible RNA helicase, mda-5, and inhibit its activation of the IFN-beta promoter. Proc. Natl. Acad. Sci. U.S.A. 101 17264-9 PubMed GONUTS page
m
s
- ssRNA negative-strand viruses
- ssRNA viruses
- GO:0039554 ! symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MDA-5 activity
- GO:0039502 ! symbiont-mediated suppression of host type I interferon-mediated signaling pathway
- GO:0039563 ! symbiont-mediated suppression of host JAK-STAT cascade via inhibition of STAT1 activity