User:Oekshyyan

My Annotations

Status	Page	Date/Time	GO Term (Aspect)	Reference	Evidence	Notes	Links
updatedbyinstructor	MOUSE:IGF2	2013-02-10 15:30:51 CST	GO:0060720 spongiotrophoblast cell proliferation (P)	PMID:22562201	ECO:0000315 mutant phenotype evidence used in manual assertion	Figure 3, along with the results section, shows that placental growth and cell proliferation was reduced in Igf2-/- mice as compared to wild type mice.	challenge
updatedbyinstructor	MOUSE:INSR	2013-02-10 17:23:13 CST	GO:0030325 adrenal gland development (P)	PMID:23300479	ECO:0000316 genetic interaction evidence used in manual assertion	Figure 6 shows that mice with an absence of Insr and Igf1r, through knockout, presented with adrenal agenesis.	challenge
correctedthroughchallenges	MOUSE:INSR	2013-02-10 17:23:13 CST	GO:0048639 positive regulation of developmental growth (P)	PMID:23300479	ECO:0000316 genetic interaction evidence used in manual assertion	Figure 1 shows that mice with the absence of Insulin receptor protein, due to gene knockout, experienced growth retardation.	challenge
updatedbyinstructor	MOUSE:INSR	2013-02-10 17:28:05 CST	GO:0008584 male gonad development (P)	PMID:23300479	ECO:0000316 genetic interaction evidence used in manual assertion	Figures 1 and 2 show that mice without INSR, due to gene knockout, experienced male to female sex reversal and disrupted testicular development.	challenge
updatedbyinstructor	MOUSE:INSR	2013-02-10 17:28:06 CST	GO:2000194 regulation of female gonad development (P)	PMID:23300479	ECO:0000316 genetic interaction evidence used in manual assertion	Figure 3 shows that mice without INSR, due to gene knockout, experienced delayed ovarian differentiation.	challenge
updatedbyinstructor	MOUSE:IGF1R	2013-02-10 17:37:14 CST	GO:0030325 adrenal gland development (P)	PMID:23300479	ECO:0000316 genetic interaction evidence used in manual assertion	Figure 6 shows that mice with an absence of INSR and IGF1R, through knockout, presented with adrenal agenesis.	challenge
updatedbyinstructor	MOUSE:IGF1R	2013-02-10 17:37:14 CST	GO:0048639 positive regulation of developmental growth (P)	PMID:23300479	ECO:0000315 mutant phenotype evidence used in manual assertion	Figure 1 shows that mice with the absence of Insulin-like growth factor 1 receptor, due to gene knockout, experienced growth retardation.	challenge
correctedthroughchallenges	MOUSE:IGF1R	2013-02-10 17:37:14 CST	GO:0008584 male gonad development (P)	PMID:23300479	ECO:0000315 mutant phenotype evidence used in manual assertion	Figures 1 and 2 show that mice without IGF1R, due to gene knockout, experienced male to female sex reversal and disrupted testicular development.	challenge
correctedthroughchallenges	MOUSE:IGF1R	2013-02-10 17:37:14 CST	GO:0001892 embryonic placenta development (P)	PMID:23300479	ECO:0000315 mutant phenotype evidence used in manual assertion	Figure 3 shows that mice without IGF1R, due to gene knockout, experienced delayed ovarian differentiation.	challenge

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unacceptable:0
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Annotations challenged by Oekshyyan

Status	Author,Group	Page	GO Term (Aspect)	Reference	Evidence	Links	Page history
acceptable	Hayat Ahmed, Team Helicases	MOUSE:GRK5	GO:0045444 - fat cell differentiation (P)	PMID:22507984	ECO:0000315 mutant phenotype evidence used in manual assertion	challenge	C: 3
unacceptable	Sswiger, Team Genetic Ninjas	MOUSE:SRY	GO:0007548 - sex differentiation (P)	PMID:7600978	ECO:0000314 direct assay evidence used in manual assertion	challenge	C: 3
acceptable	Amchugh, Team Let's Take This Outside	HUMAN:KS6A1	GO:0004674 - protein serine/threonine kinase activity (F)	PMID:22357623	ECO:0000314 direct assay evidence used in manual assertion	challenge	C: 2
acceptable	Kgreene, Team Science Dance	RAT:HAX1	GO:0016529 - sarcoplasmic reticulum (C)	PMID:19920172	ECO:0000314 direct assay evidence used in manual assertion	challenge	C: 2
unacceptable	Jlieblich, Team Let's Take This Outside	HUMAN:PTX3	GO:0030450 - regulation of complement activation, classical pathway (P)	PMID:23029266	ECO:0000314 direct assay evidence used in manual assertion	challenge	C: 1
updatedbyinstructor	Oekshyyan, Team Pancakes at Night	MOUSE:INSR	GO:0030325 - adrenal gland development (P)	PMID:23300479	ECO:0000316 genetic interaction evidence used in manual assertion	challenge	C: 4 fixed by Oekshyyan

1 annotations fixed by Oekshyyan

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