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Category:Team Pancakes at Night

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StatusPageUserDate/TimeGO Term (Aspect)ReferenceEvidenceNotesLinks
updatedbyinstructorMOUSE:IGF1ROekshyyan, Team Pancakes at Night2013-02-10 17:37:14 CSTGO:0048639 positive regulation of developmental growth (P)PMID:23300479ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 1 shows that mice with the absence of Insulin-like growth factor 1 receptor, due to gene knockout, experienced growth retardation.

challenge
correctedthroughchallengesMOUSE:IGF1ROekshyyan, Team Pancakes at Night2013-02-10 17:37:14 CSTGO:0008584 male gonad development (P)PMID:23300479ECO:0000315 mutant phenotype evidence used in manual assertion

Figures 1 and 2 show that mice without IGF1R, due to gene knockout, experienced male to female sex reversal and disrupted testicular development.

challenge
correctedthroughchallengesMOUSE:IGF1ROekshyyan, Team Pancakes at Night2013-02-10 17:37:14 CSTGO:0001892 embryonic placenta development (P)PMID:23300479ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 3 shows that mice without IGF1R, due to gene knockout, experienced delayed ovarian differentiation.

challenge
updatedbyinstructorMOUSE:IGF1ROekshyyan, Team Pancakes at Night2013-02-10 17:37:14 CSTGO:0030325 adrenal gland development (P)PMID:23300479ECO:0000316 genetic interaction evidence used in manual assertion

Figure 6 shows that mice with an absence of INSR and IGF1R, through knockout, presented with adrenal agenesis.

challenge
updatedbyinstructorMOUSE:INSROekshyyan, Team Pancakes at Night2013-02-10 17:28:06 CSTGO:2000194 regulation of female gonad development (P)PMID:23300479ECO:0000316 genetic interaction evidence used in manual assertion

Figure 3 shows that mice without INSR, due to gene knockout, experienced delayed ovarian differentiation.

challenge
updatedbyinstructorMOUSE:INSROekshyyan, Team Pancakes at Night2013-02-10 17:28:05 CSTGO:0008584 male gonad development (P)PMID:23300479ECO:0000316 genetic interaction evidence used in manual assertion

Figures 1 and 2 show that mice without INSR, due to gene knockout, experienced male to female sex reversal and disrupted testicular development.

challenge
updatedbyinstructorMOUSE:INSROekshyyan, Team Pancakes at Night2013-02-10 17:23:13 CSTGO:0030325 adrenal gland development (P)PMID:23300479ECO:0000316 genetic interaction evidence used in manual assertion

Figure 6 shows that mice with an absence of Insr and Igf1r, through knockout, presented with adrenal agenesis.

challenge
correctedthroughchallengesMOUSE:INSROekshyyan, Team Pancakes at Night2013-02-10 17:23:13 CSTGO:0048639 positive regulation of developmental growth (P)PMID:23300479ECO:0000316 genetic interaction evidence used in manual assertion

Figure 1 shows that mice with the absence of Insulin receptor protein, due to gene knockout, experienced growth retardation.

challenge
updatedbyinstructorMOUSE:IGF2Oekshyyan, Team Pancakes at Night2013-02-10 15:30:51 CSTGO:0060720 spongiotrophoblast cell proliferation (P)PMID:22562201ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 3, along with the results section, shows that placental growth and cell proliferation was reduced in Igf2-/- mice as compared to wild type mice.

challenge


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Pages in category "Team Pancakes at Night"

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