User:Bsanchez

My Annotations

Status	Page	Date/Time	GO Term (Aspect)	Reference	Evidence	Notes	Links
unacceptable	CANAL:HSP90	2014-01-29 16:22:31 CST	GO:0048523 negative regulation of cellular process (P)	PMID:23300438	ECO:0000314 direct assay evidence used in manual assertion	Hsf1 downregulats Hsp90 in C.albicans as shown in figure 1 by Western Blot	challenge
unacceptable	CANAL:Q5AQ33	2014-01-29 16:26:05 CST	GO:0048523 negative regulation of cellular process (P)	PMID:23300438	ECO:0000314 direct assay evidence used in manual assertion	Hsf1 in C.albicans negatively regulates Hsp90 during heat shock. A Western Blot in Figure 1 showing heat shock induction and non-heat shock mRNA levels of Hsp90 in the presence of Hsf1	challenge
unacceptable	CANAL:HSP90	2014-01-29 16:38:31 CST	GO:0048523 negative regulation of cellular process (P)	PMID:23300438	ECO:0000314 direct assay evidence used in manual assertion	Hsp90 in C. albicans down-regulates Hsp104 under heat shock conditions as shown in Figure 1. Hsp90 was depleted using doxycycline and mRNA levels were measured through Western Blot.	challenge
unacceptable	CANAX:Q96W69	2014-01-29 16:41:05 CST	GO:0048523 negative regulation of cellular process (P)	PMID:23300438	ECO:0000314 direct assay evidence used in manual assertion	Hsp90 in C. albicans down-regulates Hsp104 under heat shock conditions as shown in Figure 1. Hsp90 was depleted using doxycycline and mRNA levels were measured through Western Blot.	challenge
unacceptable	CANAL:HSP90	2014-01-29 16:59:29 CST	GO:0080135 regulation of cellular response to stress (P)	PMID:23300438	ECO:0000314 direct assay evidence used in manual assertion	Hsp90 in C. albicans regulates the stress response of the cells (heat shock and non-heat shock). In figure 8, Hsp90 was depleted from the cell using the drug doxycycline. When Hsp90 was depleted, the cells were less stress resistance. The stress resistance was measured by CFU (Colony-forming Unit) measurement.	challenge
unacceptable	YEAST:MLP1	2014-01-31 14:44:41 CST	GO:0090202 gene looping (P)	PMID:19933151	ECO:0000314 direct assay evidence used in manual assertion	Mlp1 is required from gene loop maintenance during glucose shutdown as shown in Figure 1 through a PolII-ChIP analysis.	challenge

acceptable:0
unacceptable:6
requires_changes:0
flagged:0

Annotations challenged by Bsanchez

Status	Author,Group	Page	GO Term (Aspect)	Reference	Evidence	Links	Page history
unacceptable	Aborel, Team Schmowzow	HUMAN:IL8	GO:0005153 - interleukin-8 receptor binding (F)	PMID:24455739	ECO:0000314 direct assay evidence used in manual assertion	challenge	C: 1
requireschanges	Chong, Team Kitten Me Right Meow	RAT:OXYR	GO:0004990 - oxytocin receptor activity (F)	PMID:22420322	ECO:0000314 direct assay evidence used in manual assertion	challenge	C: 1
unacceptable	Eturner, Team BAMF	HUMAN:M3KL4	GO:0031665 - negative regulation of lipopolysaccharide-mediated signaling pathway (P)	PMID:21602844	ECO:0000314 direct assay evidence used in manual assertion	challenge	C: 2
unacceptable	Astephens2, Team Bacon Pancakes	HUMAN:SHBG		PMID:2587256	ECO:0000247 sequence alignment evidence used in manual assertion	challenge	C: 3
unacceptable	Cford, Team What the Fox Says	HUMAN:BAD	GO:1990051 - activation of protein kinase C activity (P)	PMID:9388241	ECO:0000314 direct assay evidence used in manual assertion	challenge	C: 1

0 annotations fixed by Bsanchez

What do the icons mean in the status column?