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User:Ariana.brovarenko

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My Annotations

StatusPageDate/TimeGO Term (Aspect)ReferenceEvidenceNotesLinks
unacceptableBACSU:CHEV2012-09-20 13:02:48 CDTGO:0005622 intracellular (C)PMID:11553614ECO:0000314 direct assay evidence used in manual assertion

Figure 3 shows that more CheA-P was transfered at both temperatures than CheB. This can be proven by the darkness of the band.

challenge
acceptableECOLI:MQSR2012-09-20 13:56:56 CDTGO:2000145 quorum sensing (P)PMID:16352847ECO:0000315 mutant phenotype evidence used in manual assertion
Figure 5 shows that a mutation in the mqsR gene leads to almost no qseB transcription (qseB is a quorum sensing motility regulating 2 component regulon protein), as well as motA, another motility related gene. 
challenge
unacceptableSTRCO:GCH12012-09-20 21:13:57 CDTGO:0003934 GTP cyclohydrolase I activity (F)PMID:12000953ECO:0000314 direct assay evidence used in manual assertion

Figure 3 shows the secondary metabolites produced by S. coelicolor A3(2)

challenge
acceptableLISMO:LNTA2012-09-21 08:01:53 CDTGO:0005576 extracellular region (C)PMID:21252314ECO:0000314 direct assay evidence used in manual assertion

Figure 1. The secreted virulence factor LntA targets the nuclear protein

BAHD1.lntA is regulated by PrfA and sB.

challenge
unacceptableMICLU:UVRA2012-10-19 09:39:32 CDTGO:0006281 DNA repair (P)PMID:2549377ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 1

challenge
acceptableSHIFL:ICSB2012-10-19 21:45:59 CDTGO:0009405 pathogenesis (P)PMID:12753186ECO:0000315 mutant phenotype evidence used in manual assertion

Figures 6B and 7:IpgA is required for the secretion of IcsB by the TTSS. Whole cell lysates and CR sup. from DipgA/pTB-IcsB-IpgA, DipgA/pTB-IcsB1-494 and

DipgA grown in the presence of 0.1 mM IPTG were analysed by immunoblotting using antibodies specific for IcsB or IpgA.

challenge
unacceptableSTRMG:Q8VUG92012-10-21 10:25:57 CDTGO:0046677 response to antibiotic (P)PMID:12435673ECO:0000314 direct assay evidence used in manual assertion

Figure 1: It is showing that strain XcB2, which is a mbrD mutant, is more sensitive to bacitracin.

challenge
unacceptableECOLI:MQSR2012-11-03 19:56:08 CDTGO:2000145 regulation of cell motility (P)PMID:16352847ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 5 shows that a mutation in the mqsR gene leads to almost no qseB transcription (qseB is a quorum sensing motility regulating 2 component regulon protein), as well as motA, another motility related gene.

challenge
correctedthroughchallengesSTRMU:SUCP2012-11-04 16:29:46 CSTGO:0005985 sucrose metabolic process (P)PMID:2971020ECO:0000314 direct assay evidence used in manual assertion

Figure 3

challenge
requireschangesSTRCO:OBG2012-11-15 08:38:17 CSTGO:0006184 GTP catabolic process (P)PMID:9786189ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 8: It is proposed that a decrease in the GTP-bound form of Obg is a crucial event for triggering development in Streptomyces coelicolor.

challenge

acceptable:3
unacceptable:5
requires_changes:1
flagged:0

Annotations challenged by Ariana.brovarenko

StatusAuthor,GroupPageGO Term (Aspect)ReferenceEvidenceLinksPage history
acceptableChelsea.jenney,
Team DC2
HUMAN:MOXD1GO:0005789 - endoplasmic reticulum membrane (C)PMID:15337741ECO:0000314 direct assay evidence used in manual assertionchallengeC: 1

0 annotations fixed by Ariana.brovarenko