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ECOLI:MQSR
Contents
| Species (Taxon ID) | Escherichia coli (strain K12). (83333) | |
| Gene Name(s) | mqsR (synonyms: ygiU) | |
| Protein Name(s) | mRNA interferase MqsR
Endoribonuclease MqsR Motility quorum-sensing regulator MqsR Toxin MqsR | |
| External Links | ||
| UniProt | Q46865 | |
| EMBL | U28377 U00096 AP009048 | |
| PIR | D65089 | |
| RefSeq | NP_417494.1 YP_491214.1 | |
| PDB | 3HI2 | |
| PDBsum | 3HI2 | |
| ProteinModelPortal | Q46865 | |
| SMR | Q46865 | |
| IntAct | Q46865 | |
| STRING | 511145.b3022 | |
| EnsemblBacteria | AAC76058 BAE77078 | |
| GeneID | 12931837 947500 | |
| KEGG | ecj:Y75_p2948 eco:b3022 | |
| EchoBASE | EB2841 | |
| EcoGene | EG13023 | |
| eggNOG | NOG77853 | |
| HOGENOM | HOG000229187 | |
| KO | K13651 | |
| OMA | MEKGTPH | |
| OrthoDB | EOG6MD97N | |
| BioCyc | EcoCyc:G7572-MONOMER ECOL316407:JW2990-MONOMER MetaCyc:G7572-MONOMER | |
| PRO | PR:Q46865 | |
| Proteomes | UP000000318 UP000000625 | |
| Genevestigator | Q46865 | |
| GO | GO:0004521 GO:0045892 GO:0017148 GO:0009372 GO:0043488 GO:0090502 GO:0044010 GO:0006351 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0017148 |
negative regulation of translation |
ECO:0000315 |
P |
Fig 4A |
complete | |||||
| GO:0006379 |
mRNA cleavage |
ECO:0000315 |
P |
Fig. 4: Northern blot shows MqsR (YgiU) cleaves mRNA independently of translation. |
complete | |||||
|
involved_in |
GO:2000145 |
regulation of cell motility |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0045892 |
negative regulation of transcription, DNA-templated |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
| GO:2000145 |
quorum sensing |
ECO:0000315 |
P |
Figure 5 shows that a mutation in the mqsR gene leads to almost no qseB transcription (qseB is a quorum sensing motility regulating 2 component regulon protein), as well as motA, another motility related gene. |
complete | |||||
|
involved_in |
GO:0044010 |
single-species biofilm formation |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
| GO:2000145 |
regulation of cell motility |
ECO:0000315 |
P |
Figure 5 shows that a mutation in the mqsR gene leads to almost no qseB transcription (qseB is a quorum sensing motility regulating 2 component regulon protein), as well as motA, another motility related gene. |
complete | |||||
|
involved_in |
GO:0043488 |
regulation of mRNA stability |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
| GO:0045892 |
negative regulation of transcription, DNA-dependent |
ECO:0000315 |
P |
Figure 5 |
complete | |||||
|
involved_in |
GO:0017148 |
negative regulation of translation |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004521 |
endoribonuclease activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0090305 |
nucleic acid phosphodiester bond hydrolysis |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0004519 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0090305 |
nucleic acid phosphodiester bond hydrolysis |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0004518 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0090502 |
RNA phosphodiester bond hydrolysis, endonucleolytic |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0004521 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0009372 |
quorum sensing |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0017148 |
negative regulation of translation |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0044010 |
single-species biofilm formation |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004518 |
nuclease activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004519 |
endonuclease activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0009372 |
quorum sensing |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016787 |
hydrolase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Kasari, V et al. (2010) The Escherichia coli mqsR and ygiT genes encode a new toxin-antitoxin pair. J. Bacteriol. 192 2908-19 PubMed GONUTS page
- ↑ Christensen-Dalsgaard, M et al. (2010) Three new RelE-homologous mRNA interferases of Escherichia coli differentially induced by environmental stresses. Mol. Microbiol. 75 333-48 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 3.4 3.5 González Barrios, AF et al. (2006) Autoinducer 2 controls biofilm formation in Escherichia coli through a novel motility quorum-sensing regulator (MqsR, B3022). J. Bacteriol. 188 305-16 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 Yamaguchi, Y et al. (2009) MqsR, a crucial regulator for quorum sensing and biofilm formation, is a GCU-specific mRNA interferase in Escherichia coli. J. Biol. Chem. 284 28746-53 PubMed GONUTS page
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