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SHIFL:ICSB

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Species (Taxon ID) Shigella flexneri. (623)
Gene Name(s) icsB
Protein Name(s) Virulence protein IcsB
External Links
UniProt P33546
EMBL M86530
AL391753
AF348706
AY206439
AF386526
PIR S22687
RefSeq NP_085294.1
NP_858265.1
WP_000601049.1
YP_009078287.1
IntAct P33546
STRING 198214.CP0132
PRIDE P33546
EnsemblBacteria AAL72354
GeneID 1238057
876528
KEGG sfl:CP0132
PATRIC 18722591
eggNOG NOG147445
HOGENOM HOG000034771
KO K13790
OrthoDB EOG686ND2
Proteomes UP000001006
GO GO:0005576
GO:0009405
InterPro IPR011070
SUPFAM SSF56568

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0009405

pathogenesis

PMID:12753186[1]

ECO:0000315

P

Figures 6B and 7:IpgA is required for the secretion of IcsB by the TTSS. Whole cell lysates and CR sup. from DipgA/pTB-IcsB-IpgA, DipgA/pTB-IcsB1-494 and DipgA grown in the presence of 0.1 mM IPTG were analysed by immunoblotting using antibodies specific for IcsB or IpgA.

complete
CACAO 5401

involved_in

GO:0009405

pathogenesis

PMID:12753186[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0009405

pathogenesis

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0843

P

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0964
UniProtKB-SubCell:SL-0243

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Ogawa, M et al. (2003) IcsB, secreted via the type III secretion system, is chaperoned by IpgA and required at the post-invasion stage of Shigella pathogenicity. Mol. Microbiol. 48 913-31 PubMed GONUTS page