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Category:GO:0038128 ! ERBB2 signaling pathway

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DAG for GO:0038128id: GO:0038128

name: ERBB2 signaling pathway
namespace: biological_process
def: "A series of molecular signals initiated by binding of a ligand to a member of the ERBB family of receptors on the surface of a cell, where the signal is transmitted by ERBB2. The pathway ends with regulation of a downstream cellular process, e.g. transcription. ERBB2 receptors are themselves unable to bind to ligands, but act as a signal-amplifying tyrosine kinase within a heterodimeric pair." [GOC:jc, PMID:16460914, Reactome:R-HSA-1227986]
synonym: "ERBB2 signalling pathway" EXACT [GOC:mah]
synonym: "HER2 signaling pathway" EXACT [PR:000002082]
synonym: "NEU signaling" EXACT [Reactome:R-HSA-1227986]
synonym: "receptor tyrosine-protein kinase erbB-2 signaling pathway" EXACT [PR:000002082]
is_a: GO:0038127 ! ERBB signaling pathway

AmiGO <GOterm>GO:0038128</GOterm>
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