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Category:GO:0038128 ! ERBB2 signaling pathway
name: ERBB2 signaling pathway
namespace: biological_process
def: "The series of molecular signals initiated by binding of a ligand to the tyrosine kinase receptor ERBB2 on the surface of a cell. The pathway ends with regulation of a downstream cellular process, e.g. transcription. ERBB2 receptors are themselves unable to bind to ligands, but act as a signal-amplifying tyrosine kinase within a heterodimeric pair." [GOC:jc, PMID:16460914]
synonym: "ERBB2 signalling pathway" EXACT [GOC:mah]
synonym: "HER2 signaling pathway" EXACT [PR:000002082]
synonym: "NEU signaling" EXACT []
synonym: "receptor tyrosine-protein kinase erbB-2 signaling pathway" EXACT [PR:000002082]
is_a: GO:0038127 ! ERBB signaling pathway
AmiGO
<GOterm>GO:0038128</GOterm>
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This category has the following 3 subcategories, out of 3 total.
