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Category:GO:0038133 ! ERBB2-ERBB3 signaling pathway
name: ERBB2-ERBB3 signaling pathway
namespace: biological_process
def: "The series of molecular signals initiated by binding of a ligand to a ERBB3 receptor on the surface of a cell, followed by transmission of the signal by a heterodimeric complex of ERBB2 and ERBB3. ERBB2, which does not bind any known ligand, is activated through formation of a heterodimer with another ligand-activated ERBB family member such as ERBB3. ERBB3 also has impaired kinase activity and relies on ERBB2 for activation and signal transmission." [GOC:signaling, PMID:16460914]
synonym: "ERBB2-ERBB3 signalling pathway" EXACT [GOC:mah]
synonym: "HER2-HER3 signaling pathway" EXACT [PR:000002082, PR:000007159]
is_a: GO:0038128 ! ERBB2 signaling pathway
is_a: GO:0038129 ! ERBB3 signaling pathway
AmiGO
<GOterm>GO:0038133</GOterm>
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