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Category:GO:0004315 ! 3-oxoacyl-(acyl-carrier-protein) synthase activity
name: 3-oxoacyl-[acyl-carrier-protein] synthase activity
namespace: molecular_function
alt_id: GO:0033817
def: "Catalysis of the reaction: acyl-[acyl-carrier protein] + malonyl-[acyl-carrier protein] = 3-oxoacyl-[acyl-carrier protein] + CO2 + [acyl-carrier protein]." [RHEA:22836]
comment: Note that this activity is responsible for the chain-elongation step of dissociated (type II) fatty-acid biosynthesis, i.e. the addition of two C atoms to the fatty-acid chain. Can use fatty acyl thioesters of ACP (C2 to C16) as substrates, as well as fatty acyl thioesters of Co-A (C4 to C16).
synonym: "3-ketoacyl-acyl carrier protein synthase activity" RELATED [EC:2.3.1.41]
synonym: "3-oxoacyl-[acyl-carrier protein] synthase activity" EXACT []
synonym: "3-oxoacyl-ACP synthase activity" EXACT []
synonym: "3-oxoacyl-acyl carrier protein synthase I activity" NARROW [EC:2.3.1.179]
synonym: "3-oxoacyl-acyl-carrier-protein synthase activity" RELATED [EC:2.3.1.41]
synonym: "acyl-acyl-carrier-protein:malonyl-acyl-carrier-protein C-acyltransferase (decarboxylating)" RELATED [EC:2.3.1.41]
synonym: "acyl-malonyl acyl carrier protein-condensing enzyme activity" RELATED [EC:2.3.1.41]
synonym: "acyl-malonyl(acyl-carrier-protein)-condensing enzyme activity" RELATED [EC:2.3.1.41]
synonym: "beta-ketoacyl acyl carrier protein synthase activity" RELATED [EC:2.3.1.41]
synonym: "beta-ketoacyl synthetase activity" RELATED [EC:2.3.1.41]
synonym: "beta-ketoacyl-[acyl carrier protein] synthase activity" RELATED [EC:2.3.1.41]
synonym: "beta-ketoacyl-ACP synthase I activity" NARROW [EC:2.3.1.41]
synonym: "beta-ketoacyl-ACP synthase II activity" NARROW [EC:2.3.1.179]
synonym: "beta-ketoacyl-ACP synthetase activity" RELATED [EC:2.3.1.41]
synonym: "beta-ketoacyl-acyl carrier protein synthase activity" RELATED [EC:2.3.1.41]
synonym: "beta-ketoacyl-acyl carrier protein synthetase activity" RELATED [EC:2.3.1.41]
synonym: "beta-ketoacyl-acyl-carrier-protein synthase I" NARROW [EC:2.3.1.41]
synonym: "beta-ketoacyl-acyl-carrier-protein synthase II activity" NARROW []
synonym: "beta-ketoacylsynthase activity" RELATED [EC:2.3.1.41]
synonym: "condensing enzyme activity" BROAD [EC:2.3.1.41]
synonym: "fatty acid condensing enzyme activity" BROAD [EC:2.3.1.41]
synonym: "ketoacyl-ACP synthase activity" EXACT []
xref: EC:2.3.1.41
xref: MetaCyc:3-OXOACYL-ACP-SYNTH-RXN
xref: RHEA:22836
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
AmiGO
<GOterm>GO:0004315</GOterm>
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