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ECOBD:A0A140N913

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Species (Taxon ID) Escherichia coli (strain B / BL21-DE3). (469008)
Gene Name(s) fabH (ECO:0000256 with HAMAP-Rule:MF_01815)
Protein Name(s) 3-oxoacyl-[acyl-carrier-protein] synthase 3 (ECO:0000256 with HAMAP-Rule:MF_01815)

3-oxoacyl-[acyl-carrier-protein] synthase III (ECO:0000256 with HAMAP-Rule:MF_01815) Beta-ketoacyl-ACP synthase III (ECO:0000256 with HAMAP-Rule:MF_01815) KAS III (ECO:0000256 with HAMAP-Rule:MF_01815)

External Links
UniProt A0A140N913
EMBL CP001665
RefSeq WP_000288146.1
ProteinModelPortal A0A140N913
SMR A0A140N913
EnsemblBacteria ACT29532
KEGG ebd:ECBD_2510
ebe:B21_01095
ebl:ECD_01087
PATRIC fig|469008.15.peg.1117
KO K00648
OMA IGPTVWG
UniPathway UPA00094
Proteomes UP000002032
GO GO:0005737
GO:0004315
GO:0033818
GO:0006633
Gene3D 3.40.47.10
HAMAP MF_01815
InterPro IPR013751
IPR013747
IPR004655
IPR016039
Pfam PF08545
PF08541
SUPFAM SSF53901
TIGRFAMs TIGR00747

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0044579

butyryl-CoA biosynthetic process from acetyl-CoA

PMID:26305336[1]

ECO:0000315

P

Addition of EcFabH or RsFabH to the reaction mixture led to formation of butyryl-ACP (S1B fig, lane 1 and lane 2). Upon addition of the long chain E. coli 3-ketoacyl-ACP synthase I, FabB, to the reactions, all reactions produced long chain acyl-ACP species (S1B fig, lane 3 and lane 4). This data supports the notion that like E. coli FabH, RsFabH could complete the initial cycle of fatty acid synthesis to produce butyryl-ACP.

Organism & Strain: E. coli (strain B / BL21-DE3)

complete
CACAO 12956

enables

GO:0003824

catalytic activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR016039

F

Seeded From UniProt

complete

enables

GO:0004315

3-oxoacyl-[acyl-carrier-protein] synthase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004655
InterPro:IPR013751

F

Seeded From UniProt

complete

involved_in

GO:0006633

fatty acid biosynthetic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004655
InterPro:IPR013751

P

Seeded From UniProt

complete

enables

GO:0033818

beta-ketoacyl-acyl-carrier-protein synthase III activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:2.3.1.180

F

Seeded From UniProt

complete

enables

GO:0016746

transferase activity, transferring acyl groups

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0012

F

Seeded From UniProt

complete

enables

GO:0016740

transferase activity

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

involved_in

GO:0006633

fatty acid biosynthetic process

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0275

P

Seeded From UniProt

complete

involved_in

GO:0006629

lipid metabolic process

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0443

P

Seeded From UniProt

complete

enables

GO:0003824

catalytic activity

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0511

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0963

C

Seeded From UniProt

complete

involved_in

GO:0006631

fatty acid metabolic process

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0276

P

Seeded From UniProt

complete

involved_in

GO:0008152

metabolic process

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0511

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000040

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

enables

GO:0033818

beta-ketoacyl-acyl-carrier-protein synthase III activity

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000085060

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000085060

C

Seeded From UniProt

complete

involved_in

GO:0006633

fatty acid biosynthetic process

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000085060

P

Seeded From UniProt

complete

involved_in

GO:0006633

fatty acid biosynthetic process

GO_REF:0000041

ECO:0000322

imported manually asserted information used in automatic assertion

UniPathway:UPA00094

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Mao, YH et al. (2015) Ralstonia solanacearum RSp0194 Encodes a Novel 3-Keto-Acyl Carrier Protein Synthase III. PLoS ONE 10 e0136261 PubMed GONUTS page

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Internal error

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[b0929972338aefc3061e600f] /wiki/index.php/ECOBD:A0A140N913 Error from line 252 of /usr/local/github/wiki-extensions/wiki-extensions-hulab/AnnotationLinks/AnnotationLinks.php: Call to a member function getIdentifier() on null

Backtrace:

#0 /usr/local/github/wiki-extensions/wiki-extensions-hulab/AnnotationLinks/AnnotationLinks.php(70): AnnotationLinks::getQuickGOannotations(string, array)
#1 /var/www/html/go/wiki/includes/parser/Parser.php(3888): AnnotationLinks::renderAnnotations(NULL, array, Parser, PPFrame_DOM)
#2 /var/www/html/go/wiki/includes/parser/Preprocessor_DOM.php(1362): Parser->extensionSubstitution(array, PPFrame_DOM)
#3 /var/www/html/go/wiki/includes/parser/Parser.php(2942): PPFrame_DOM->expand(DOMElement, integer)
#4 /var/www/html/go/wiki/includes/parser/Parser.php(1293): Parser->replaceVariables(string)
#5 /var/www/html/go/wiki/includes/parser/Parser.php(443): Parser->internalParse(string)
#6 /var/www/html/go/wiki/includes/content/WikitextContent.php(323): Parser->parse(string, Title, ParserOptions, boolean, boolean, integer)
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#8 /var/www/html/go/wiki/includes/content/ContentHandler.php(1324): AbstractContent->getParserOutput(Title, integer, ParserOptions)
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#10 /usr/local/github/wiki-extensions/wiki-extensions-hulab/CirrusSearch/includes/Updater.php(407): CirrusSearch\Updater::buildDocument(CirrusSearch, WikiPage, CirrusSearch\Connection, integer, integer, integer)
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#12 /usr/local/github/wiki-extensions/wiki-extensions-hulab/CirrusSearch/includes/Updater.php(83): CirrusSearch\Updater->updatePages(array, integer)
#13 /usr/local/github/wiki-extensions/wiki-extensions-hulab/CirrusSearch/includes/Job/LinksUpdate.php(52): CirrusSearch\Updater->updateFromTitle(Title)
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#21 /var/www/html/go/wiki/includes/MediaWiki.php(750): MediaWiki->{closure}()
#22 /var/www/html/go/wiki/includes/MediaWiki.php(557): MediaWiki->doPostOutputShutdown(string)
#23 /var/www/html/go/wiki/index.php(42): MediaWiki->run()
#24 {main}

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