ECOBD:A0A140N913

Species (Taxon ID)	Escherichia coli (strain B / BL21-DE3). (469008)
Gene Name(s)	fabH (ECO:0000256 with HAMAP-Rule:MF_01815)
Protein Name(s)	3-oxoacyl-[acyl-carrier-protein] synthase 3 (ECO:0000256 with HAMAP-Rule:MF_01815) 3-oxoacyl-[acyl-carrier-protein] synthase III (ECO:0000256 with HAMAP-Rule:MF_01815) Beta-ketoacyl-ACP synthase III (ECO:0000256 with HAMAP-Rule:MF_01815) KAS III (ECO:0000256 with HAMAP-Rule:MF_01815)
External Links
UniProt	A0A140N913
EMBL	CP001665
RefSeq	WP_000288146.1
ProteinModelPortal	A0A140N913
SMR	A0A140N913
EnsemblBacteria	ACT29532
KEGG	ebd:ECBD_2510 ebe:B21_01095 ebl:ECD_01087
PATRIC	fig|469008.15.peg.1117
KO	K00648
OMA	IGPTVWG
UniPathway	UPA00094
Proteomes	UP000002032
GO	GO:0005737 GO:0004315 GO:0033818 GO:0006633
Gene3D	3.40.47.10
HAMAP	MF_01815
InterPro	IPR013751 IPR013747 IPR004655 IPR016039
Pfam	PF08545 PF08541
SUPFAM	SSF53901
TIGRFAMs	TIGR00747

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0044579	butyryl-CoA biosynthetic process from acetyl-CoA	PMID:26305336	ECO:0000315			P		Addition of EcFabH or RsFabH to the reaction mixture led to formation of butyryl-ACP (S1B fig, lane 1 and lane 2). Upon addition of the long chain E. coli 3-ketoacyl-ACP synthase I, FabB, to the reactions, all reactions produced long chain acyl-ACP species (S1B fig, lane 3 and lane 4). This data supports the notion that like E. coli FabH, RsFabH could complete the initial cycle of fatty acid synthesis to produce butyryl-ACP. Organism & Strain: E. coli (strain B / BL21-DE3)	complete CACAO 12956
enables	GO:0003824	catalytic activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR016039	F		Seeded From UniProt	complete
enables	GO:0004315	3-oxoacyl-[acyl-carrier-protein] synthase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR004655 InterPro:IPR013751	F		Seeded From UniProt	complete
involved_in	GO:0006633	fatty acid biosynthetic process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR004655 InterPro:IPR013751	P		Seeded From UniProt	complete
enables	GO:0033818	beta-ketoacyl-acyl-carrier-protein synthase III activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:2.3.1.180	F		Seeded From UniProt	complete
enables	GO:0016746	transferase activity, transferring acyl groups	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0012	F		Seeded From UniProt	complete
enables	GO:0016740	transferase activity	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0808	F		Seeded From UniProt	complete
involved_in	GO:0006633	fatty acid biosynthetic process	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0275	P		Seeded From UniProt	complete
involved_in	GO:0006629	lipid metabolic process	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0443	P		Seeded From UniProt	complete
enables	GO:0003824	catalytic activity	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0511	F		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0963	C		Seeded From UniProt	complete
involved_in	GO:0006631	fatty acid metabolic process	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0276	P		Seeded From UniProt	complete
involved_in	GO:0008152	metabolic process	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0511	P		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000040	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-SubCell:SL-0086	C		Seeded From UniProt	complete
enables	GO:0033818	beta-ketoacyl-acyl-carrier-protein synthase III activity	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000085060	F		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000085060	C		Seeded From UniProt	complete
involved_in	GO:0006633	fatty acid biosynthetic process	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000085060	P		Seeded From UniProt	complete
involved_in	GO:0006633	fatty acid biosynthetic process	GO_REF:0000041	ECO:0000322	imported manually asserted information used in automatic assertion	UniPathway:UPA00094	P		Seeded From UniProt	complete
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