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ECOLI:FABF
Contents
| Species (Taxon ID) | Escherichia coli (strain K12). (83333) | |
| Gene Name(s) | fabF (synonyms: fabJ) | |
| Protein Name(s) | 3-oxoacyl-[acyl-carrier-protein] synthase 2
3-oxoacyl-[acyl-carrier-protein] synthase II Beta-ketoacyl-ACP synthase II KAS II | |
| External Links | ||
| UniProt | P0AAI5 | |
| EMBL | Z34979 U20767 U00096 AP009048 | |
| PIR | I41060 | |
| RefSeq | NP_415613.1 YP_489363.1 | |
| PDB | 1B3N 1KAS 2GFV 2GFW 2GFX 2GFY 3G0Y 3G11 3HNZ 3HO2 3HO9 3I8P | |
| PDBsum | 1B3N 1KAS 2GFV 2GFW 2GFX 2GFY 3G0Y 3G11 3HNZ 3HO2 3HO9 3I8P | |
| ProteinModelPortal | P0AAI5 | |
| SMR | P0AAI5 | |
| DIP | DIP-29377N | |
| IntAct | P0AAI5 | |
| MINT | MINT-1231688 | |
| STRING | 511145.b1095 | |
| DrugBank | DB01034 | |
| PaxDb | P0AAI5 | |
| PRIDE | P0AAI5 | |
| EnsemblBacteria | AAC74179 BAA35903 | |
| GeneID | 12931078 946665 | |
| KEGG | ecj:Y75_p1065 eco:b1095 | |
| PATRIC | 32117431 | |
| EchoBASE | EB2490 | |
| EcoGene | EG12606 | |
| eggNOG | COG0304 | |
| HOGENOM | HOG000060165 | |
| InParanoid | P0AAI5 | |
| KO | K09458 | |
| OMA | MGPNYTT | |
| OrthoDB | EOG6DG2SR | |
| PhylomeDB | P0AAI5 | |
| BioCyc | EcoCyc:3-OXOACYL-ACP-SYNTHII-MONOMER ECOL316407:JW1081-MONOMER MetaCyc:3-OXOACYL-ACP-SYNTHII-MONOMER | |
| BRENDA | 2.3.1.179 | |
| SABIO-RK | P0AAI5 | |
| UniPathway | UPA00094 | |
| EvolutionaryTrace | P0AAI5 | |
| PRO | PR:P0AAI5 | |
| Proteomes | UP000000318 UP000000625 | |
| Genevestigator | P0AAI5 | |
| GO | GO:0005829 GO:0004315 GO:0033817 GO:0006633 | |
| Gene3D | 3.40.47.10 | |
| InterPro | IPR017568 IPR018201 IPR014031 IPR014030 IPR016039 IPR016038 | |
| Pfam | PF00109 PF02801 | |
| PIRSF | PIRSF000447 | |
| SUPFAM | SSF53901 | |
| TIGRFAMs | TIGR03150 | |
| PROSITE | PS00606 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0033817 |
beta-ketoacyl-acyl-carrier-protein synthase II activity |
ECO:0000314 |
F |
Figures 1, 2, and 3 show that the fabF mutant (fabF1) activity is decreased by expressing F-ACP. The decrease in activity can be seen by the banding pattern seen after running samples through gel electrophoresis. Wild type fabF cells show increased activity by expressing ACP, and the mutants show a lack of activity by expressing F-ACP. |
complete | |||||
|
enables |
GO:0033817 |
beta-ketoacyl-acyl-carrier-protein synthase II activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005829 |
cytosol |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006633 |
fatty acid biosynthetic process |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG10274 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG10274 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004315 |
3-oxoacyl-[acyl-carrier-protein] synthase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG10274 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0033817 |
beta-ketoacyl-acyl-carrier-protein synthase II activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004315 |
3-oxoacyl-[acyl-carrier-protein] synthase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003824 |
catalytic activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006633 |
fatty acid biosynthetic process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016747 |
transferase activity, transferring acyl groups other than amino-acyl groups |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0033817 |
beta-ketoacyl-acyl-carrier-protein synthase II activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006629 |
lipid metabolic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016740 |
transferase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016746 |
transferase activity, transferring acyl groups |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006633 |
fatty acid biosynthetic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0275 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006631 |
fatty acid metabolic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Jackowski, S & Rock, CO (1987) Altered molecular form of acyl carrier protein associated with beta-ketoacyl-acyl carrier protein synthase II (fabF) mutants. J. Bacteriol. 169 1469-73 PubMed GONUTS page
- ↑ Lasserre, JP et al. (2006) A complexomic study of Escherichia coli using two-dimensional blue native/SDS polyacrylamide gel electrophoresis. Electrophoresis 27 3306-21 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ Garwin, JL et al. (1980) Structural, enzymatic, and genetic studies of beta-ketoacyl-acyl carrier protein synthases I and II of Escherichia coli. J. Biol. Chem. 255 11949-56 PubMed GONUTS page
- ↑ D'Agnolo, G et al. (1975) Multiple forms of beta-ketoacyl-acyl carrier protein synthetase in Escherichia coli. J. Biol. Chem. 250 5289-94 PubMed GONUTS page
