PSEAE:PQSD

Species (Taxon ID)	Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228). (208964)
Gene Name(s)	pqsD
Protein Name(s)	2-heptyl-4(1H)-quinolone synthase PqsD PqsD
External Links
UniProt	P20582
EMBL	AE004091 M33810
PIR	B83522 D35116
RefSeq	NP_249690.1
PDB	3H76 3H77 3H78
PDBsum	3H76 3H77 3H78
ProteinModelPortal	P20582
SMR	P20582
STRING	208964.PA0999
DNASU	880625
EnsemblBacteria	AAG04388
GeneID	880625
KEGG	pae:PA0999
PATRIC	19836288
PseudoCAP	PA0999
eggNOG	COG0332
HOGENOM	HOG000246674
InParanoid	P20582
KO	K18003
OMA	PATACMV
OrthoDB	EOG6J74XN
PhylomeDB	P20582
BioCyc	MetaCyc:MONOMER-16011
EvolutionaryTrace	P20582
Proteomes	UP000002438
GO	GO:0005737 GO:0004315 GO:0016746 GO:0006633 GO:0044550
Gene3D	3.40.47.10
InterPro	IPR013751 IPR013747 IPR016039 IPR016038
Pfam	PF08545 PF08541
SUPFAM	SSF53901

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0004315	3-oxoacyl-[acyl-carrier-protein] synthase activity	PMID:18728009	ECO:0000314			F		Figure 2 shows DHQ formation by PqsD in Vitro. Mutant strains showed PqsD was a part of DHQ synthesis in vivo and was further tested in vitro. Anthraniloyl-CoA was produced in situ by PqsA and reacted with malonyl-CoA (a product of PqsD) to form DHQ as supported by TLC and LC-MS. These tests confirm DHQ formation when compared against the DHQ standard. Figure 7 shows the proposed mechanism for DHQ synthesis with the products of the Pqs gene.	complete CACAO 7692
enables	GO:0016746	transferase activity, transferring acyl groups	PMID:18728009	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0044550	secondary metabolite biosynthetic process	PMID:18728009	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0044550	secondary metabolite biosynthetic process	PMID:12426334	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0016746	transferase activity, transferring acyl groups	PMID:18728009	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0003824	catalytic activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR016039	F		Seeded From UniProt	complete
enables	GO:0004315	3-oxoacyl-[acyl-carrier-protein] synthase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR013751	F		Seeded From UniProt	complete
involved_in	GO:0006633	fatty acid biosynthetic process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR013751	P		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0963 UniProtKB-SubCell:SL-0086	C		Seeded From UniProt	complete
enables	GO:0016740	transferase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0808	F		Seeded From UniProt	complete
enables	GO:0016746	transferase activity, transferring acyl groups	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0012	F		Seeded From UniProt	complete
edit table

References

See Help:References for how to manage references in GONUTS.