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ECOLI:FABB
Contents
| Species (Taxon ID) | Escherichia coli (strain K12). (83333) | |
| Gene Name(s) | fabB (synonyms: fabC) | |
| Protein Name(s) | 3-oxoacyl-[acyl-carrier-protein] synthase 1
3-oxoacyl-[acyl-carrier-protein] synthase I Beta-ketoacyl-ACP synthase I KAS I | |
| External Links | ||
| UniProt | P0A953 | |
| EMBL | M24427 AJ012161 AJ012162 AJ012163 U00096 AP009048 | |
| PIR | A31284 | |
| RefSeq | NP_416826.1 WP_000817178.1 | |
| PDB | 1DD8 1EK4 1F91 1FJ4 1FJ8 1G5X 1H4F 2AQ7 2AQB 2BUH 2BUI 2BYW 2BYX 2BYY 2BYZ 2BZ3 2BZ4 2CDH 2CF2 2VB7 2VB8 2VB9 2VBA 5KOF | |
| PDBsum | 1DD8 1EK4 1F91 1FJ4 1FJ8 1G5X 1H4F 2AQ7 2AQB 2BUH 2BUI 2BYW 2BYX 2BYY 2BYZ 2BZ3 2BZ4 2CDH 2CF2 2VB7 2VB8 2VB9 2VBA 5KOF | |
| ProteinModelPortal | P0A953 | |
| SMR | P0A953 | |
| BioGrid | 4260793 | |
| DIP | DIP-29379N | |
| IntAct | P0A953 | |
| STRING | 316385.ECDH10B_2485 | |
| BindingDB | P0A953 | |
| ChEMBL | CHEMBL4913 | |
| DrugBank | DB08359 DB04519 DB01034 DB03600 DB03017 | |
| SwissLipids | SLP:000001786 | |
| EPD | P0A953 | |
| jPOST | P0A953 | |
| PaxDb | P0A953 | |
| PRIDE | P0A953 | |
| EnsemblBacteria | AAC75383 BAA16180 | |
| GeneID | 946799 | |
| KEGG | ecj:JW2320 eco:b2323 | |
| PATRIC | fig|1411691.4.peg.4409 | |
| EchoBASE | EB0270 | |
| EcoGene | EG10274 | |
| eggNOG | ENOG4105C0Q COG0304 | |
| HOGENOM | HOG000060165 | |
| InParanoid | P0A953 | |
| KO | K00647 | |
| PhylomeDB | P0A953 | |
| BioCyc | EcoCyc:FABB-MONOMER MetaCyc:FABB-MONOMER | |
| BRENDA | 2.3.1.41 | |
| UniPathway | UPA00094 | |
| EvolutionaryTrace | P0A953 | |
| PRO | PR:P0A953 | |
| Proteomes | UP000000318 UP000000625 | |
| GO | GO:0005829 GO:0004315 GO:0006633 GO:0008610 | |
| Gene3D | 3.40.47.10 | |
| InterPro | IPR018201 IPR014031 IPR014030 IPR020841 IPR016039 | |
| Pfam | PF00109 PF02801 | |
| SMART | SM00825 | |
| SUPFAM | SSF53901 | |
| PROSITE | PS00606 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
part_of |
GO:0005829 |
cytosol |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006633 |
fatty acid biosynthetic process |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG10274 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG10274 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004315 |
3-oxoacyl-[acyl-carrier-protein] synthase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG10274 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0008610 |
lipid biosynthetic process |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
EcoliWiki:fadD |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006633 |
fatty acid biosynthetic process |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
EcoliWiki:fadD |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006633 |
fatty acid biosynthetic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004315 |
3-oxoacyl-[acyl-carrier-protein] synthase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003824 |
catalytic activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004315 |
3-oxoacyl-[acyl-carrier-protein] synthase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016740 |
transferase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006629 |
lipid metabolic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006633 |
fatty acid biosynthetic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0275 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0016746 |
transferase activity, transferring acyl groups |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006631 |
fatty acid metabolic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Lasserre, JP et al. (2006) A complexomic study of Escherichia coli using two-dimensional blue native/SDS polyacrylamide gel electrophoresis. Electrophoresis 27 3306-21 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ 3.0 3.1 Feng, Y & Cronan, JE (2009) Escherichia coli unsaturated fatty acid synthesis: complex transcription of the fabA gene and in vivo identification of the essential reaction catalyzed by FabB. J. Biol. Chem. 284 29526-35 PubMed GONUTS page
- ↑ Jackowski, S et al. (2002) A missense mutation in the fabB (beta-ketoacyl-acyl carrier protein synthase I) gene confers tiolactomycin resistance to Escherichia coli. Antimicrob. Agents Chemother. 46 1246-52 PubMed GONUTS page
- ↑ Ishihama, Y et al. (2008) Protein abundance profiling of the Escherichia coli cytosol. BMC Genomics 9 102 PubMed GONUTS page
- ↑ Lopez-Campistrous, A et al. (2005) Localization, annotation, and comparison of the Escherichia coli K-12 proteome under two states of growth. Mol. Cell Proteomics 4 1205-9 PubMed GONUTS page
- ↑ Garwin, JL et al. (1980) Structural, enzymatic, and genetic studies of beta-ketoacyl-acyl carrier protein synthases I and II of Escherichia coli. J. Biol. Chem. 255 11949-56 PubMed GONUTS page
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