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User:Rossira1

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SUPER BOWL (Round 5)

My Annotations

StatusPageDate/TimeGO Term (Aspect)ReferenceEvidenceNotesLinks
requireschangesSTAAW:CLPP2012-04-10 11:51:05 CDTGO:0008462 endopeptidase Clp activity (F)PMID:21969594ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 2 shows septum formation inhibition in those wild type species treated with antibiotic, in mutant clp species septum formation is able to occur even when treated with an antibiotic.

challenge
requireschangesHUMAN:BACE12012-04-11 09:52:09 CDTGO:0008233 peptidase activity (F)PMID:22449099ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 1 shows that the activity of BACE-1 is actively involved in the cleave of ST6Gal I from the Golgi membrane inducing secretion. Mutants without BACE-1 activity could not induce the cleavage of ST6Gal I and no secretion occurred.

challenge
requireschangesSCHPO:CCQ12012-04-11 13:52:38 CDTGO:0071573 telosome assembly (P)PMID:19141478ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 1 shows that mutants without Ccq1 are unable to recruit telomerase to the telomerase in vivo.

challenge
acceptableSCHPO:ATM2012-04-11 14:05:42 CDTGO:0004672 protein kinase activity (F)PMID:22302936ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 2 show that Tel 1 is required for phosphorylation of Thr 93 of Ccq1. Mutants without Tel 1 were unable to phosphorylate Ccq1.

challenge
acceptableSCHPO:RAD32012-04-11 14:09:28 CDTGO:0004672 protein kinase activity (F)PMID:22302936ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 2A,E show that mutants without Rad3 were unable to phosphorylate Thr93 of Ccq1 and those with Rad3 were able to phosphorylate Thr93 of Ccq1.

challenge
requireschangesECOLI:MSBA2012-04-15 13:26:51 CDTGO:0004012 phospholipid-translocating ATPase activity (F)PMID:2888566ECO:0000314 direct assay evidence used in manual assertion

Figure 2 shows E.coli and different membranes, with and with out ATP and the distribution of phospholipid membranes when MsbA is incorporated into the membrane.

challenge
requireschangesECOLI:RSMA2012-04-15 14:22:09 CDTGO:0019104 DNA N-glycosylase activity (F)PMID:2673420ECO:0000314 direct assay evidence used in manual assertion

Figure 5 shows cleavage of nucleotides on miss-paired bases when KsgA is added.

challenge

acceptable:2
unacceptable:0
requires_changes:5
flagged:0

Annotations challenged by Rossira1

StatusAuthor,GroupPageGO Term (Aspect)ReferenceEvidenceLinksPage history

0 annotations fixed by Rossira1


MSU Internal

My Annotations

StatusPageDate/TimeGO Term (Aspect)ReferenceEvidenceNotesLinks
updatedbyinstructorMOUSE:BCCIP2012-03-27 12:07:45 CDTGO:0006974 cellular response to DNA damage stimulus (P)PMID:21966279ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 7. BCCIP Knockdown cells exhibit greater growth inhibition by irradiation compared to control.

challenge
requireschanges?2012-03-29 11:14:03 CDTGO:0008375 acetylglucosaminyltransferase activity (Fig 4. Shows and assay of recombinant species what oxt gene and product produced when substrate added)PMID:11929872IDA: Inferred from Direct Assay
challenge

acceptable:0
unacceptable:0
requires_changes:1
flagged:0

Annotations challenged by Rossira1

StatusAuthor,GroupPageGO Term (Aspect)ReferenceEvidenceLinksPage history

0 annotations fixed by Rossira1