User:Patelrh3

My Annotations

Status	Page	Date/Time	GO Term (Aspect)	Reference	Evidence	Notes	Links
unacceptable	PLAFK:DRTS	2016-05-02 09:28:16 CDT	GO:0004799 thymidylate synthase activity (F)	PMID:12704428	ECO:0000314 direct assay evidence used in manual assertion	Panel B in Figure 2 establishes the activity of Thymidylate Synthase in Plasmodium falciparium dihydrofolate reductase-thymidylate synthase. Figure 2 shows the junction region of alpha helix as a docking element onto the DHFR-TS domain interface. The long-range electrostatic interactions are among the major forces attracting the negatively charged alpha helix of a TS domain to the surface groove lined with positively charged amino acids from the helices of the DHFR domain.	challenge
unacceptable	CAEEL:Q9Y052	2016-04-27 19:12:03 CDT	GO:0004799 thymidylate synthase activity (F)	other:GO_REF:0000100	ECO:0000255 match to sequence model evidence used in manual assertion	HHPred results yielded an E-value of 3.8e-89, an identity of 100%, a probability of 100%, and a query coverage of 94.46%.	challenge
unacceptable	HUMAN:TYSY	2016-04-27 19:20:48 CDT	GO:0004799 thymidylate synthase activity (F)	other:GO_REF:0000100	ECO:0000255 match to sequence model evidence used in manual assertion	HHPred results yielded an E-value of 2.1e-88, an identity of 100%, a probability of 100%, and a query coverage of 97.07%.	challenge
unacceptable	TRISP:Q9NDD3	2016-04-27 19:29:10 CDT	GO:0004799 thymidylate synthase activity (F)	other:GO_REF:0000100	ECO:0000255 match to sequence model evidence used in manual assertion	HHPred results yielded an E-value of 3.3e-88, an identity of 100%, a probability of 100%, and a query coverage of 97.07%.	challenge
unacceptable	PNECA:TYSY	2016-04-27 19:37:42 CDT	GO:0004799 thymidylate synthase activity (F)	other:GO_REF:0000100	ECO:0000255 match to sequence model evidence used in manual assertion	HHPred results yielded an E-value of 1.7e-87, an identity of 100%, a probability of 100%, and a query coverage of 93.81%.	challenge
unacceptable	CRYNJ:TYSY	2016-04-27 19:47:49 CDT	GO:0004799 thymidylate synthase activity (F)	other:GO_REF:0000100	ECO:0000255 match to sequence model evidence used in manual assertion	HHPred results yielded an E-value of 2.6e-87, an identity of 100%, a probability of 100%, and a query coverage of 97.39%.	challenge
unacceptable	ENCCU:TYS1	2016-04-27 20:48:55 CDT	GO:0004799 thymidylate synthase activity (F)	other:GO_REF:0000100	ECO:0000255 match to sequence model evidence used in manual assertion	HHPred results yielded an E-value of 9.2e-88, an identity of 100%, a probability of 100%, and a query coverage of 94.46%.	challenge

acceptable:0
unacceptable:7
requires_changes:0
flagged:0

Annotations challenged by Patelrh3

Status	Author,Group	Page	GO Term (Aspect)	Reference	Evidence	Links	Page history
acceptable	Eleo1, Team Red B	BPTU2:Q9AYV6	GO:0098023 - virus tail, tip (C)	PMID:15150235	ECO:0000314 direct assay evidence used in manual assertion	challenge	C: 4
unacceptable	Mnguy1, Team Blue B	BACTU:A0A0G3E6U5	GO:0016301 - kinase activity (BlastP sequence alignment showed an E value of 7E-54 )	PMID:11292795	ISS: Inferred from Sequence Similarity UniProtKB:A0A0G3E6U5	challenge	C: 3
unacceptable	Hoang5, Team Purple A	9CAUD:A0A0K2D0I8	GO:0004309 - exopolyphosphatase activity (F)	PMID:10498723	ECO:0000315 mutant phenotype evidence used in manual assertion	challenge	C: 3
unacceptable	Hossaira, Team Phiesty Phages	9CAUD:A0A024B1F7	GO:0098005 - viral head-tail joining (P)	PMID:7483254	ECO:0000250 sequence similarity evidence used in manual assertion	challenge	C: 4
unacceptable	Mnguy1, Team Blue B	BPT7:DPOL	GO:0004527 - exonuclease activity (F)	2703498:2703498	ECO:0000315 mutant phenotype evidence used in manual assertion	challenge	C: 5
unacceptable	Odilia1, Team Green B	BPT4:D9IEK2	GO:0019012 - virion (C)	PMID:2963141	ECO:0000314 direct assay evidence used in manual assertion	challenge	C: 3

0 annotations fixed by Patelrh3

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