User:Brackmic

My Annotations

Status	Page	Date/Time	GO Term (Aspect)	Reference	Evidence	Notes	Links
updatedbyinstructor	STRC0:Q6DNI4	2014-04-06 15:30:20 CDT	GO:0004340 glucokinase activity (F)	PMID:24687748	ECO:0000314 direct assay evidence used in manual assertion	Figure 1.	challenge
unacceptable	MOUSE:Q5SVI6	2014-04-06 16:14:07 CDT	GO:0004340 glucokinase activity (F)	PMID:23291412	ECO:0000315 mutant phenotype evidence used in manual assertion	Figure 1 a. shows higher blood glucose levels in mice with the Gck knockdown then in those mice with wild type Gck.	challenge
unacceptable	MOUSE:Q5SVI6	2014-04-06 16:29:05 CDT	GO:0004340 glucokinase activity (F)	PMID:23085254	ECO:0000315 mutant phenotype evidence used in manual assertion	Figure 1 a. shows that the Gck knockdown mice have higher blood glucose levels then in those mice with wild type Gck genotype after 2 weeks of age.	challenge
requireschanges	MOUSE:Q5SVI6	2014-04-06 16:53:00 CDT	GO:0004340 glucokinase activity (F)	PMID:10512368	ECO:0000315 mutant phenotype evidence used in manual assertion	Figure 1 a & b show an increase in the glucose phosoralation capacity of mice infused with the adenovirus containing mouse GK cDNA as opposed to mice infused with adenovirus containing either a bacterial beta-galactosidase gene or a 2.4-kb B a mHI cDNA fragment encoding full-length human GK with impaired the catalytic activity due to a point mutation.	challenge
unacceptable	RAT:HXK4	2014-04-06 17:42:01 CDT	GO:0004340 glucokinase activity (F)	PMID:10593862	ECO:0000315 mutant phenotype evidence used in manual assertion	Figure 4. shows that rats enhanced with adenoviruses containing the cDNA encoding rat liver glucokinase (AdCMV-GKL) more efficiently cleared the glucose bolus than the unenhanced rats or the rats enhanced with adenoviruses containing the cDNA encoding Escherichia coli b-galactosidase nls-LacZ gene (AdCMV-lacZ). Rats with higher levels of Glucokinase enhancement cleared the bolus more efficiently than those with lower levels of Glucokinase enhancement.	challenge

acceptable:0
unacceptable:3
requires_changes:1
flagged:0

Annotations challenged by Brackmic

Status	Author,Group	Page	GO Term (Aspect)	Reference	Evidence	Links	Page history
updatedbyinstructor	Min.lorna, Team Ood	PSEAE:BEKAS	GO:0061990 (F)	PMID:22753057	ECO:0000315 mutant phenotype evidence used in manual assertion	challenge	C: 1
updatedbyinstructor	Min.lorna, Team Ood	LACRD:A5VK67	GO:0045893 - positive regulation of DNA-templated transcription (P)	PMID:24123819	ECO:0000315 mutant phenotype evidence used in manual assertion	challenge	C: 1
updatedbyinstructor	Min.lorna, Team Ood	LACRD:A5VK67	GO:0046775 - obsolete suppression by virus of host cytokine production (P)	PMID:24123819	ECO:0000315 mutant phenotype evidence used in manual assertion	challenge	C: 2
updatedbyinstructor	Brookelle.christman, Team A5	STAAU:C7BUR8	GO:0016020 - membrane (C)	PMID:19851500	ECO:0000315 mutant phenotype evidence used in manual assertion	challenge	C: 2

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