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User:Brookelle.christman

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CACAO Spring 2014

My Annotations

StatusPageDate/TimeGO Term (Aspect)ReferenceEvidenceNotesLinks
flaggedSTAAR:FNBA2014-03-20 13:17:42 CDTGO:0042710 biofilm formation (P)PMID:18375547ECO:0000315 mutant phenotype evidence used in manual assertion

Fig. 4 shows fnbpA contributes to glucose induced biofilm development of S. aureus

challenge
unacceptableSTAAE:A6QJY92014-03-20 13:43:20 CDTGO:0005576 extracellular region (C)PMID:13278487ECO:0000315 mutant phenotype evidence used in manual assertion

Table 5:

Compares the conditions required for absorption and clumping between fibrinogen and antibodies produced by Staphylococcus aureus species

challenge
unacceptableSTAA8:ARLS2014-03-20 14:04:14 CDTGO:0008236 serine-type peptidase activity (F)PMID:10869073ECO:0000315 mutant phenotype evidence used in manual assertion

Table 2:

The mutant showed less extracellular proteolytic activity. Which is responsible for increased autolysis of mutant cells.

challenge
unacceptableSTAAU:HLA2014-03-20 14:16:20 CDTGO:0009405 pathogenesis (P)PMID:11454217ECO:0000315 mutant phenotype evidence used in manual assertion

Table 2:

Hla production is expressed at much higher levels in the mutants used in the experiment than those of the wildtypes. This information concluded that the arl operon increases the production of virulence factor proteins.

challenge
unacceptableSTAA3:Q2FF572014-03-20 14:31:09 CDTGO:0003824 catalytic activity (F)PMID:19188357ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 3 (C&D):

Sigma factor B is needed for biofilm formation in S aureus.

challenge
updatedbyinstructorSTAAU:C7BUR82014-03-20 14:49:35 CDTGO:0016020 membrane (C)PMID:19851500ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 8:

When the expression of the sasC gene products were inhibited in a S. aureus strain, biofilm production was reduced in comparison to the S. aureus wild type strain.

challenge
updatedbyinstructorSTAA8:Q2FWJ12014-04-04 12:23:53 CDTGO:0044011 single-species biofilm formation on inanimate substrate (P)PMID:19188357ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 3 (C&D):

Sigma factor B is needed for biofilm formation in S aureus.

challenge
unacceptableSTAA8:ARLS2014-04-04 12:34:16 CDTGO:0009405 pathogenesis (P)PMID:10869073ECO:0000315 mutant phenotype evidence used in manual assertion

Table 2:

The mutant showed less extracellular proteolytic activity, which is responsible for increased autolysis of mutant cells.

challenge
unacceptableSTAAU:C7BUR82014-04-04 12:41:40 CDTGO:1900233 positive regulation of single-species biofilm formation on inanimate substrate (P)PMID:19851500ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 8:

When the expression of the sasC gene products were inhibited in an S. aureus strain, biofilm production was reduced in comparison to the S. aureus wild type strain.

challenge

acceptable:0
unacceptable:6
requires_changes:0
flagged:1

Annotations challenged by Brookelle.christman

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0 annotations fixed by Brookelle.christman

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