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STAA8:ARLS
Contents
| Species (Taxon ID) | Staphylococcus aureus (strain NCTC 8325). (93061) | |
| Gene Name(s) | arlS | |
| Protein Name(s) | Signal transduction histidine-protein kinase ArlS | |
| External Links | ||
| UniProt | Q9KJN3 | |
| EMBL | AF165314 CP000253 | |
| RefSeq | WP_000166801.1 YP_499945.1 | |
| ProteinModelPortal | Q9KJN3 | |
| SMR | Q9KJN3 | |
| STRING | 93061.SAOUHSC_01419 | |
| EnsemblBacteria | ABD30512 | |
| GeneID | 3920650 | |
| KEGG | sao:SAOUHSC_01419 | |
| PATRIC | 19580277 | |
| eggNOG | COG0642 | |
| HOGENOM | HOG000223177 | |
| OMA | INIWIAN | |
| OrthoDB | EOG6G4VQG | |
| BioCyc | SAUR93061:GIWJ-1359-MONOMER | |
| Proteomes | UP000008816 | |
| GO | GO:0016021 GO:0005886 GO:0005524 GO:0000155 GO:0009405 | |
| Gene3D | 1.10.287.130 3.30.565.10 | |
| InterPro | IPR003661 IPR003660 IPR003594 IPR004358 IPR005467 IPR009082 | |
| Pfam | PF00672 PF02518 PF00512 | |
| PRINTS | PR00344 | |
| SMART | SM00304 SM00387 SM00388 | |
| SUPFAM | SSF47384 SSF55874 | |
| PROSITE | PS50885 PS50109 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0008236 |
serine-type peptidase activity |
ECO:0000315 |
F |
Table 2: The mutant showed less extracellular proteolytic activity. Which is responsible for increased autolysis of mutant cells. |
complete | |||||
| GO:0043709 |
cell adhesion involved in single-species biofilm formation |
ECO:0000315 |
P |
Fig. 2: arlS mutant (BF16) formed a film on surface of microtiter plates, no such film was seen in plates with wild-type and complemented strains |
complete | |||||
| GO:0009405 |
pathogenesis |
ECO:0000315 |
P |
Table 2: The mutant showed less extracellular proteolytic activity, which is responsible for increased autolysis of mutant cells. |
complete | |||||
| GO:0000155 |
phosphorelay sensor kinase activity |
ECO:0000315 |
F |
Table 2. The mutant showed less extracellular proteolytic activity. Which is responsible for increased autolysis of mutant cell |
complete | |||||
| GO:0008236 |
serine-type peptidase activity |
ECO:0000315 |
F |
Table 2 Arls mutant strains showed a decrease in serine protease activity and an increase in autolysin activity when exposed to a serine protease inhibitor |
complete | |||||
|
enables |
GO:0008236 |
serine-type peptidase activity |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0046777 |
protein autophosphorylation |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG13646 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0009927 |
histidine phosphotransfer kinase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN001976860 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005887 |
integral component of plasma membrane |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN001976860 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004673 |
protein histidine kinase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
CGD:CAL0000175114 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0000155 |
phosphorelay sensor kinase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG13646 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006508 |
proteolysis |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0008236 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0018106 |
peptidyl-histidine phosphorylation |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0004673 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0018106 |
peptidyl-histidine phosphorylation |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0004673 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0023014 |
signal transduction by protein phosphorylation |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0000155 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0023014 |
signal transduction by protein phosphorylation |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0000155 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0000155 |
phosphorelay sensor kinase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007165 |
signal transduction |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0016310 |
phosphorylation |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016772 |
transferase activity, transferring phosphorus-containing groups |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004673 |
protein histidine kinase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016740 |
transferase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0000160 |
phosphorelay signal transduction system |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016301 |
kinase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0016310 |
phosphorylation |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0009405 |
pathogenesis |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0000166 |
nucleotide binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005524 |
ATP binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Fournier, B & Hooper, DC (2000) A new two-component regulatory system involved in adhesion, autolysis, and extracellular proteolytic activity of Staphylococcus aureus. J. Bacteriol. 182 3955-64 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
p
- GO:0018106 ! peptidyl-histidine phosphorylation
- GO:0000160 ! phosphorelay signal transduction system
- GO:0000155 ! phosphorelay sensor kinase activity
- GO:0016310 ! phosphorylation
- GO:0005886 ! plasma membrane
- GO:0046777 ! protein autophosphorylation
- GO:0004673 ! protein histidine kinase activity
- GO:0006508 ! proteolysis
s
