STAAU:HLA

Species (Taxon ID)	Staphylococcus aureus. (1280)
Gene Name(s)	hly (synonyms: hla)
Protein Name(s)	Alpha-hemolysin Alpha-HL Alpha-toxin
External Links
UniProt	P09616
EMBL	X01645 M90536
PIR	S69209
PDB	3M2L 3M3R 3M4D 3M4E 4IDJ 7AHL
PDBsum	3M2L 3M3R 3M4D 3M4E 4IDJ 7AHL
ProteinModelPortal	P09616
SMR	P09616
DIP	DIP-59322N
ChEMBL	CHEMBL1075259
TCDB	1.C.3.1.1
eggNOG	NOG41533
Reactome	REACT_75808
EvolutionaryTrace	P09616
PMAP-CutDB	P09616
PRO	PR:P09616
GO	GO:0005576 GO:0044179 GO:0009405
Gene3D	2.70.240.10
InterPro	IPR005831 IPR003963 IPR016183
Pfam	PF07968
PRINTS	PR01468
SUPFAM	SSF56959
TIGRFAMs	TIGR01002
PROSITE	PS00274

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
enables	GO:0042802	identical protein binding		ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:P09616	F		Seeded From UniProt	complete
enables	GO:0042802	identical protein binding		ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:P09616	F		Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR003963 InterPro:IPR005831 InterPro:IPR016183	C		Seeded From UniProt	complete
involved_in	GO:0009405	pathogenesis	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR003963	P		Seeded From UniProt	complete
involved_in	GO:0051715	cytolysis in other organism	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR016183	P		Seeded From UniProt	complete
	GO:0009405	pathogenesis	PMID:11454217	ECO:0000315			P		Table 2: Hla production is expressed at much higher levels in the mutants used in the experiment than those of the wildtypes. This information concluded that the arl operon increases the production of virulence factor proteins.	complete CACAO 9622
part_of	GO:0005576	extracellular region	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0964 UniProtKB-SubCell:SL-0243	C		Seeded From UniProt	complete
enables	GO:0090729	toxin activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0800	F		Seeded From UniProt	complete
involved_in	GO:0019835	cytolysis	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0204	P		Seeded From UniProt	complete
involved_in	GO:0044179	hemolysis in other organism	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0354	P		Seeded From UniProt	complete
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References

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