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Category:Team Triple Bond

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StatusPageUserDate/TimeGO Term (Aspect)ReferenceEvidenceNotesLinks
acceptableMOUSE:VTNCPatric.daugherty, Team Triple Bond2012-11-18 16:52:48 CSTGO:0048709 oligodendrocyte differentiation (P)PMID:23155445ECO:0000314 direct assay evidence used in manual assertion

Figure 7a

challenge
unacceptableARATH:TRXM3Patric.daugherty, Team Triple Bond2012-11-18 16:42:47 CSTGO:0048709 oligodendrocyte differentiation (P)PMID:23155445ECO:0000315 mutant phenotype evidence used in manual assertion

figure 2

challenge
unacceptableARATH:TRXM3Patric.daugherty, Team Triple Bond2012-11-18 16:39:58 CSTGO:0048709 oligodendrocyte differentiation (P)PMID:23155445ECO:0000315 mutant phenotype evidence used in manual assertion

figure 1

challenge
requireschangesMOUSE:ASPMAndrea.messina, Team Triple Bond2012-11-17 13:00:08 CSTGO:0060236 regulation of mitotic spindle organization (P)PMID:23152892ECO:0000314 direct assay evidence used in manual assertion

Figure 4.shows "Downregulation of ASPM expression by morpholinos disrupts meiotic spindle organization."

challenge
requireschangesHUMAN:PHF1Andrea.messina, Team Triple Bond2012-11-17 12:55:42 CSTGO:0001867 complement activation, lectin pathway (P)PMID:23150668ECO:0000314 direct assay evidence used in manual assertion

FIGURE #1 shows that "PHF1 specifically activates p53 pathway" therefore regulating cell growth and apoptosis.

challenge
acceptableMOUSE:MYOD1Andrea.messina, Team Triple Bond2012-11-17 12:54:45 CSTGO:0010468 regulation of gene expression (P)PMID:22740650ECO:0000314 direct assay evidence used in manual assertion

Figure #1 shows "MyoD co-induces the expression of p57 and kcnq1 during muscle differentiation"

challenge
unacceptableRAT:MAP1BAndrea.messina, Team Triple Bond2012-11-17 12:53:38 CSTGO:0007165 signal transduction (P)PMID:23152929ECO:0000314 direct assay evidence used in manual assertion

Figure 1 shows "The light chains of MAP1B and MAP1A interact with α1-syntrophin."

challenge
acceptableMOUSE:GPNMBEllie.detrich, Team Triple Bond2012-11-15 18:29:41 CSTGO:0032720 negative regulation of tumor necrosis factor production (P)PMID:17475886ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 9

challenge
acceptablePSEAE:LASREllie.detrich, Team Triple Bond2012-11-15 18:26:15 CSTGO:0045893 positive regulation of transcription, DNA-dependent (P)PMID:9150205ECO:0000314 direct assay evidence used in manual assertion

Figure 4. In the absence of LasR or PAI-1, rhlR expression remained at background level, but in the presence of both LasR and PAI-1, rhlR expression increased approximately threefold, indicating that rhlR was directly controlled by LasR and PAI-1.

challenge
requireschangesRAT:LITAFEllie.detrich, Team Triple Bond2012-09-23 10:56:21 CDTGO:0050663 cytokine secretion (P)PMID:17475886ECO:0000314 direct assay evidence used in manual assertion

Figure 7B

challenge
requireschangesRAT:GPNMBEllie.detrich, Team Triple Bond2012-09-23 10:40:24 CDTGO:0050727 regulation of inflammatory response (P)PMID:22574278ECO:0000315 mutant phenotype evidence used in manual assertion

Figures 4, 6-8

challenge
requireschangesMOUSE:GPNMBEllie.detrich, Team Triple Bond2012-09-23 10:27:05 CDTGO:0032715 negative regulation of interleukin-6 production (P)PMID:17475886ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 9

challenge
requireschangesMOUSE:GPNMBEllie.detrich, Team Triple Bond2012-09-23 10:27:05 CDTGO:0032695 negative regulation of interleukin-12 production (P)PMID:17475886ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 9

challenge
requireschangesPSEAE:LASREllie.detrich, Team Triple Bond2012-09-23 09:34:47 CDTGO:0010468 transcription, DNA-dependent (P)PMID:179088ECO:0000316 genetic interaction evidence used in manual assertion

Figure 1

challenge
requireschangesPSEAE:LASREllie.detrich, Team Triple Bond2012-09-20 21:29:33 CDTGO:0005667 transcription factor complex (C)PMID:179088ECO:0000316 genetic interaction evidence used in manual assertion

From figures 2,3, and 4. The LasR–PAI-1 complex is a global regulator of P. aeruginosa virulence.

challenge
acceptablePSEAE:VFREllie.detrich, Team Triple Bond2012-09-18 23:38:12 CDTGO:0006351 transcription, DNA-templated (P)PMID:9190808ECO:0000315 mutant phenotype evidence used in manual assertion

TABLE 3. Effect of Vfr on lasR expression in P. aeruginosa

challenge


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Pages in category "Team Triple Bond"

The following 3 pages are in this category, out of 3 total.


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