MOUSE:MYOD1

Species (Taxon ID)	Mus musculus (Mouse). (10090)
Gene Name(s)	Myod1 (synonyms: Myod)
Protein Name(s)	Myoblast determination protein 1
External Links
UniProt	P10085
EMBL	M18779 X61655 M84918 AK076157 AK142859 BC103613 BC103618 BC103619
CCDS	CCDS21277.1
PIR	A29636
RefSeq	NP_034996.2
UniGene	Mm.1526
PDB	1MDY
PDBsum	1MDY
ProteinModelPortal	P10085
SMR	P10085
BioGrid	201673
DIP	DIP-37N
IntAct	P10085
MINT	MINT-263097
STRING	10090.ENSMUSP00000072330
PhosphoSite	P10085
PRIDE	P10085
Ensembl	ENSMUST00000072514
GeneID	17927
KEGG	mmu:17927
UCSC	uc012fkv.1
CTD	4654
MGI	MGI:97275
eggNOG	NOG292792
GeneTree	ENSGT00530000063004
HOGENOM	HOG000234800
HOVERGEN	HBG006429
InParanoid	P10085
KO	K09064
OMA	DPRLMHV
OrthoDB	EOG76QFK1
TreeFam	TF316344
Reactome	REACT_258600
EvolutionaryTrace	P10085
NextBio	292797
PRO	PR:P10085
Proteomes	UP000000589
Bgee	P10085
CleanEx	MM_MYOD1
Genevestigator	P10085
GO	GO:0005737 GO:0030016 GO:0000790 GO:0005654 GO:0005634 GO:0005667 GO:0031490 GO:0001047 GO:0003677 GO:0019899 GO:0046982 GO:0000978 GO:0001077 GO:0003705 GO:0001228 GO:0043565 GO:0003700 GO:0008134 GO:0031625 GO:0055007 GO:0071392 GO:0071385 GO:0071453 GO:0009267 GO:0043966 GO:0043967 GO:0007517 GO:0045445 GO:0007518 GO:0014908 GO:1901741 GO:0043415 GO:0045944 GO:0045893 GO:0000381 GO:0006357 GO:0035914 GO:0043503 GO:0048741 GO:0007519 GO:0051146 GO:0006366
Gene3D	4.10.280.10
InterPro	IPR002546 IPR011598 IPR022032
Pfam	PF01586 PF00010 PF12232
SMART	SM00520 SM00353
SUPFAM	SSF47459
PROSITE	PS50888

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0010468	regulation of gene expression	PMID:22740650^[1]	ECO:0000314			P		Figure #1 shows "MyoD co-induces the expression of p57 and kcnq1 during muscle differentiation"	complete CACAO 6024
involved_in	GO:1905382	positive regulation of snRNA transcription by RNA polymerase II	PMID:25217815^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:1990841	promoter-specific chromatin binding	PMID:25217815^[2]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0051149	positive regulation of muscle cell differentiation	PMID:16901893^[3]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0045944	positive regulation of transcription by RNA polymerase II	PMID:16901893^[3]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:16901893^[3]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
enables	GO:0003682	chromatin binding	PMID:16245309^[4]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0003713	transcription coactivator activity	PMID:12037670^[5]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0010468	regulation of gene expression	PMID:22740650^[1]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	GO_REF:0000036	ECO:0000305	curator inference used in manual assertion	GO:0000978,GO:0045944	F	occurs_at:(SO:0001952)	Seeded From UniProt	complete
enables	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding	PMID:11714687^[6]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0019899	enzyme binding	PMID:20833138^[7]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:Q6ZQ88	F		Seeded From UniProt	complete
part_of	GO:0000790	nuclear chromatin	PMID:20833138^[7]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0071392	cellular response to estradiol stimulus	PMID:15706034^[8]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0055007	cardiac muscle cell differentiation	PMID:21556048^[9]	ECO:0000303	author statement without traceable support used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0045944	positive regulation of transcription by RNA polymerase II	PMID:15706034^[8]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0043967	histone H4 acetylation	PMID:15706034^[8]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0043966	histone H3 acetylation	PMID:15706034^[8]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0035914	skeletal muscle cell differentiation	PMID:21556048^[9]	ECO:0000303	author statement without traceable support used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0031490	chromatin DNA binding	PMID:15706034^[8]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0008134	transcription factor binding	PMID:2503252^[10]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:P15923-1	F		Seeded From UniProt	complete
part_of	GO:0005667	transcription factor complex	PMID:2503252^[10]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:20139084^[11]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
contributes_to	GO:0003677	DNA binding	PMID:2503252^[10]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0070888	E-box binding	PMID:15706034^[8]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:1901741	positive regulation of myoblast fusion	PMID:21873635^[12]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000164853 UniProtKB:P15172	P		Seeded From UniProt	complete
involved_in	GO:0048743	positive regulation of skeletal muscle fiber development	PMID:21873635^[12]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:97276 PANTHER:PTN000898840	P		Seeded From UniProt	complete
involved_in	GO:0045944	positive regulation of transcription by RNA polymerase II	PMID:21873635^[12]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:97252 MGI:MGI:97275 MGI:MGI:97276 PANTHER:PTN000164853 RGD:620432 UniProtKB:P15172 UniProtKB:P15173 UniProtKB:P16075 UniProtKB:P17920 UniProtKB:Q01795 WB:WBGene00001948	P		Seeded From UniProt	complete
involved_in	GO:0045663	positive regulation of myoblast differentiation	PMID:21873635^[12]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:97276 PANTHER:PTN000164853	P		Seeded From UniProt	complete
involved_in	GO:0035914	skeletal muscle cell differentiation	PMID:21873635^[12]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:97252 MGI:MGI:97253 MGI:MGI:97275 PANTHER:PTN000898840 ZFIN:ZDB-GENE-980526-561	P		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:21873635^[12]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0002922 MGI:MGI:97275 MGI:MGI:97276 PANTHER:PTN000164853 RGD:620432 RGD:631429 WB:WBGene00001948	C		Seeded From UniProt	complete
enables	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	PMID:21873635^[12]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:97252 MGI:MGI:97253 MGI:MGI:97275 MGI:MGI:97276 PANTHER:PTN000164853 UniProtKB:P15172 UniProtKB:P15173	F		Seeded From UniProt	complete
enables	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding	PMID:21873635^[12]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:97275 MGI:MGI:97276 PANTHER:PTN000164853 RGD:620432	F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:2000818	negative regulation of myoblast proliferation	PMID:15890200^[13]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:1901741	positive regulation of myoblast fusion	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P15172	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0071453	cellular response to oxygen levels	PMID:19319192^[14]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0071385	cellular response to glucocorticoid stimulus	PMID:19319192^[14]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0071356	cellular response to tumor necrosis factor	PMID:24349514^[15]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0070888	E-box binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:631429	F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0051149	positive regulation of muscle cell differentiation	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P15172	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0051146	striated muscle cell differentiation	PMID:17028574^[16]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	occurs_in:(EMAPA:35578)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0048741	skeletal muscle fiber development	PMID:19319192^[14]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	results_in_development_of:(CL:0002372)	Seeded From UniProt	complete
enables	GO:0046982	protein heterodimerization activity	PMID:15572127^[17]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:P15806	F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045944	positive regulation of transcription by RNA polymerase II	PMID:24301466^[18]	ECO:0000316	genetic interaction evidence used in manual assertion	MGI:MGI:103296	P	has_regulation_target:(MGI:MGI:1339709) has_regulation_target:(MGI:MGI:2155600) occurs_in:(CL:0002372) regulates_o_occurs_in:(CL:0002372)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045944	positive regulation of transcription by RNA polymerase II	PMID:24301466^[18]	ECO:0000316	genetic interaction evidence used in manual assertion	MGI:MGI:102463	P	has_regulation_target:(MGI:MGI:1339712) occurs_in:(EMAPA:35866) regulates_o_occurs_in:(EMAPA:35866)\|regulates_o_occurs_in:(CL:0002372) occurs_in:(CL:0002372) has_regulation_target:(MGI:MGI:1339712)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045944	positive regulation of transcription by RNA polymerase II	PMID:21832073^[19]	ECO:0000316	genetic interaction evidence used in manual assertion	MGI:MGI:1289184	P	has_regulation_target:(MGI:MGI:97276)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045944	positive regulation of transcription by RNA polymerase II	PMID:18676376^[20]	ECO:0000316	genetic interaction evidence used in manual assertion	MGI:MGI:103296	P	has_regulation_target:(MGI:MGI:97276)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045944	positive regulation of transcription by RNA polymerase II	PMID:15743821^[21]	ECO:0000316	genetic interaction evidence used in manual assertion	MGI:MGI:99458 UniProtKB:P20695 UniProtKB:P56524	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045944	positive regulation of transcription by RNA polymerase II	PMID:15572127^[17]	ECO:0000316	genetic interaction evidence used in manual assertion	MGI:MGI:1926387	P	has_regulation_target:(MGI:MGI:88413)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045944	positive regulation of transcription by RNA polymerase II	PMID:22638570^[22]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045944	positive regulation of transcription by RNA polymerase II	PMID:7659522^[23]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045944	positive regulation of transcription by RNA polymerase II	PMID:25640239^[24]	ECO:0000314	direct assay evidence used in manual assertion		P	has_regulation_target:(MGI:MGI:1916813)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045944	positive regulation of transcription by RNA polymerase II	PMID:17940050^[25]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045944	positive regulation of transcription by RNA polymerase II	PMID:17855775^[26]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045944	positive regulation of transcription by RNA polymerase II	PMID:12486129^[27]	ECO:0000314	direct assay evidence used in manual assertion		P	has_regulation_target:(MGI:MGI:109617)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045944	positive regulation of transcription by RNA polymerase II	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P15172	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045893	positive regulation of transcription, DNA-templated	PMID:17904117^[28]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045893	positive regulation of transcription, DNA-templated	PMID:15520228^[29]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045893	positive regulation of transcription, DNA-templated	PMID:12782625^[30]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045445	myoblast differentiation	PMID:12486129^[27]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045445	myoblast differentiation	PMID:12037571^[31]	ECO:0000314	direct assay evidence used in manual assertion		P	results_in_acquisition_of_features_of:(CL:0000057)	Seeded From UniProt	complete
enables	GO:0043565	sequence-specific DNA binding	PMID:25640239^[24]	ECO:0000314	direct assay evidence used in manual assertion		F	has_input:(MGI:MGI:1916813)	Seeded From UniProt	complete
enables	GO:0043565	sequence-specific DNA binding	PMID:22638570^[22]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0043503	skeletal muscle fiber adaptation	PMID:19319192^[14]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	occurs_in:(CL:0002372)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0043484	regulation of RNA splicing	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P15172	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0043415	positive regulation of skeletal muscle tissue regeneration	PMID:17028574^[16]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	regulates_o_occurs_in:(EMAPA:35578)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0043403	skeletal muscle tissue regeneration	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:631429	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0035914	skeletal muscle cell differentiation	PMID:22147266^[32]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0035257	nuclear hormone receptor binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P15172	F		Seeded From UniProt	complete
enables	GO:0031625	ubiquitin protein ligase binding	PMID:19319192^[14]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:Q78JE5	F		Seeded From UniProt	complete
enables	GO:0031490	chromatin DNA binding	PMID:25085416^[33]	ECO:0000314	direct assay evidence used in manual assertion		F	has_output:(MGI:MGI:1913389)	Seeded From UniProt	complete
part_of	GO:0030016	myofibril	PMID:21131290^[34]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0030016	myofibril	PMID:19319192^[14]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0016604	nuclear body	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P15172	C		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0014908	myotube differentiation involved in skeletal muscle regeneration	PMID:1348494^[35]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	results_in_acquisition_of_features_of:(CL:0002372)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0014904	myotube cell development	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P15172	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0014902	myotube differentiation	PMID:9234731^[36]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0009267	cellular response to starvation	PMID:19319192^[14]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0008134	transcription factor binding	PMID:24301466^[18]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:Q60591	F		Seeded From UniProt	complete
enables	GO:0008134	transcription factor binding	PMID:22638570^[22]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:Q8C208	F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0007520	myoblast fusion	PMID:15890200^[13]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0007519	skeletal muscle tissue development	PMID:8269513^[37]	ECO:0000316	genetic interaction evidence used in manual assertion	MGI:MGI:97252	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0007519	skeletal muscle tissue development	PMID:12895031^[38]	ECO:0000316	genetic interaction evidence used in manual assertion	MGI:MGI:94909	P	results_in_development_of:(EMAPA:17701)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0007519	skeletal muscle tissue development	PMID:19531352^[39]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:1857221	P	results_in_development_of:(EMAPA:31858)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0007519	skeletal muscle tissue development	PMID:14762206^[40]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0007519	skeletal muscle tissue development	PMID:12037571^[31]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0007518	myoblast fate determination	PMID:12486129^[27]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0007517	muscle organ development	PMID:15634692^[41]	ECO:0000316	genetic interaction evidence used in manual assertion	MGI:MGI:97252	P	results_in_development_of:(EMAPA:17743)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0007517	muscle organ development	PMID:15192231^[42]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0006357	regulation of transcription by RNA polymerase II	PMID:19796622^[43]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005829	cytosol	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P15172	C		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	PMID:19319192^[14]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005654	nucleoplasm	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P15172	C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:22358842^[44]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(CL:0000056)\|part_of:(CL:0002372)	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:19796622^[43]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:19319192^[14]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:12878168^[45]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:11711431^[46]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:631429	C		Seeded From UniProt	complete
enables	GO:0003700	DNA-binding transcription factor activity	PMID:12486129^[27]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0003682	chromatin binding	PMID:24301466^[18]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0003682	chromatin binding	PMID:18676376^[20]	ECO:0000314	direct assay evidence used in manual assertion		F	has_direct_input:(MGI:MGI:97276)	Seeded From UniProt	complete
enables	GO:0003677	DNA binding	PMID:19121967^[47]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0003677	DNA binding	PMID:12486129^[27]	ECO:0000314	direct assay evidence used in manual assertion		F	has_participant:(MGI:MGI:109617)	Seeded From UniProt	complete
enables	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	PMID:15890200^[13]	ECO:0000315	mutant phenotype evidence used in manual assertion		F	has_regulation_target:(MGI:MGI:104564) has_regulation_target:(MGI:MGI:1861447) has_regulation_target:(MGI:MGI:1339467) occurs_in:(CL:0000056) regulates_o_occurs_in:(CL:0000056)	Seeded From UniProt	complete
enables	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	PMID:24361185^[48]	ECO:0000314	direct assay evidence used in manual assertion		F	has_regulation_target:(MGI:MGI:1919580)	Seeded From UniProt	complete
enables	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P15172	F		Seeded From UniProt	complete
enables	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P15172	F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0000381	regulation of alternative mRNA splicing, via spliceosome	PMID:9525963^[49]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0000381	regulation of alternative mRNA splicing, via spliceosome	PMID:9525963^[49]	ECO:0000314	direct assay evidence used in manual assertion		P	regulates_o_occurs_in:(CL:0000057)	Seeded From UniProt	complete
involved_in	GO:1901741	positive regulation of myoblast fusion	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15172 ensembl:ENSP00000250003	P		Seeded From UniProt	complete
involved_in	GO:0051149	positive regulation of muscle cell differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15172 ensembl:ENSP00000250003	P		Seeded From UniProt	complete
involved_in	GO:0045944	positive regulation of transcription by RNA polymerase II	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15172 ensembl:ENSP00000250003	P		Seeded From UniProt	complete
involved_in	GO:0043484	regulation of RNA splicing	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15172 ensembl:ENSP00000250003	P		Seeded From UniProt	complete
enables	GO:0035257	nuclear hormone receptor binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15172 ensembl:ENSP00000250003	F		Seeded From UniProt	complete
part_of	GO:0016604	nuclear body	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15172 ensembl:ENSP00000250003	C		Seeded From UniProt	complete
involved_in	GO:0014904	myotube cell development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15172 ensembl:ENSP00000250003	P		Seeded From UniProt	complete
part_of	GO:0005829	cytosol	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15172 ensembl:ENSP00000250003	C		Seeded From UniProt	complete
part_of	GO:0005654	nucleoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15172 ensembl:ENSP00000250003	C		Seeded From UniProt	complete
enables	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15172 ensembl:ENSP00000250003	F		Seeded From UniProt	complete
enables	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15172 ensembl:ENSP00000250003	F		Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002546	F		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002546	C		Seeded From UniProt	complete
involved_in	GO:0006355	regulation of transcription, DNA-templated	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002546 InterPro:IPR039704	P		Seeded From UniProt	complete
involved_in	GO:0007517	muscle organ development	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002546 InterPro:IPR039704	P		Seeded From UniProt	complete
enables	GO:0046983	protein dimerization activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR011598 InterPro:IPR036638	F		Seeded From UniProt	complete
part_of	GO:0005654	nucleoplasm	Reactome:R-MMU-448949	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0007519	skeletal muscle tissue development	PMID:1846704^[50]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:1846704^[50]	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
enables	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	PMID:1846704^[50]	ECO:0000304	author statement supported by traceable reference used in manual assertion		F		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0539 UniProtKB-SubCell:SL-0191	C		Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0238	F		Seeded From UniProt	complete
involved_in	GO:0007275	multicellular organism development	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0217	P		Seeded From UniProt	complete
involved_in	GO:0007517	muscle organ development	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0517	P		Seeded From UniProt	complete
involved_in	GO:0030154	cell differentiation	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0221	P		Seeded From UniProt	complete
edit table

Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 Busanello, A et al. (2012) MyoD regulates p57kip2 expression by interacting with a distant cis-element and modifying a higher order chromatin structure. Nucleic Acids Res. 40 8266-75 PubMed GONUTS page
↑ ^2.0 ^2.1 Grifone, R et al. (2014) The RNA-binding protein Rbm24 is transiently expressed in myoblasts and is required for myogenic differentiation during vertebrate development. Mech. Dev. 134 1-15 PubMed GONUTS page
↑ ^3.0 ^3.1 ^3.2 Wilson, EM & Rotwein, P (2006) Control of MyoD function during initiation of muscle differentiation by an autocrine signaling pathway activated by insulin-like growth factor-II. J. Biol. Chem. 281 29962-71 PubMed GONUTS page
↑ Giacinti, C et al. (2006) MyoD recruits the cdk9/cyclin T2 complex on myogenic-genes regulatory regions. J. Cell. Physiol. 206 807-13 PubMed GONUTS page
↑ Simone, C et al. (2002) Activation of MyoD-dependent transcription by cdk9/cyclin T2. Oncogene 21 4137-48 PubMed GONUTS page
↑ Wang, DZ et al. (2001) The Mef2c gene is a direct transcriptional target of myogenic bHLH and MEF2 proteins during skeletal muscle development. Development 128 4623-33 PubMed GONUTS page
↑ ^7.0 ^7.1 Choi, J et al. (2010) Histone demethylase LSD1 is required to induce skeletal muscle differentiation by regulating myogenic factors. Biochem. Biophys. Res. Commun. 401 327-32 PubMed GONUTS page
↑ ^8.0 ^8.1 ^8.2 ^8.3 ^8.4 ^8.5 Blais, A et al. (2005) An initial blueprint for myogenic differentiation. Genes Dev. 19 553-69 PubMed GONUTS page
↑ ^9.0 ^9.1 Al Madhoun, AS et al. (2011) Skeletal myosin light chain kinase regulates skeletal myogenesis by phosphorylation of MEF2C. EMBO J. 30 2477-89 PubMed GONUTS page
↑ ^10.0 ^10.1 ^10.2 Murre, C et al. (1989) Interactions between heterologous helix-loop-helix proteins generate complexes that bind specifically to a common DNA sequence. Cell 58 537-44 PubMed GONUTS page
↑ Stuelsatz, P et al. (2010) Down-regulation of MyoD by calpain 3 promotes generation of reserve cells in C2C12 myoblasts. J. Biol. Chem. 285 12670-83 PubMed GONUTS page
↑ ^12.0 ^12.1 ^12.2 ^12.3 ^12.4 ^12.5 ^12.6 ^12.7 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
↑ ^13.0 ^13.1 ^13.2 Bean, C et al. (2005) The Ankrd2, Cdkn1c and calcyclin genes are under the control of MyoD during myogenic differentiation. J. Mol. Biol. 349 349-66 PubMed GONUTS page
↑ ^14.0 ^14.1 ^14.2 ^14.3 ^14.4 ^14.5 ^14.6 ^14.7 ^14.8 Lagirand-Cantaloube, J et al. (2009) Inhibition of atrogin-1/MAFbx mediated MyoD proteolysis prevents skeletal muscle atrophy in vivo. PLoS ONE 4 e4973 PubMed GONUTS page
↑ Lee, H et al. (2013) MicroRNA-494, upregulated by tumor necrosis factor-α, desensitizes insulin effect in C2C12 muscle cells. PLoS ONE 8 e83471 PubMed GONUTS page
↑ ^16.0 ^16.1 Duquet, A et al. (2006) Acetylation is important for MyoD function in adult mice. EMBO Rep. 7 1140-6 PubMed GONUTS page
↑ ^17.0 ^17.1 Cole, F et al. (2004) Positive regulation of myogenic bHLH factors and skeletal muscle development by the cell surface receptor CDO. Dev. Cell 7 843-54 PubMed GONUTS page
↑ ^18.0 ^18.1 ^18.2 ^18.3 Daou, N et al. (2013) A new role for the calcineurin/NFAT pathway in neonatal myosin heavy chain expression via the NFATc2/MyoD complex during mouse myogenesis. Development 140 4914-25 PubMed GONUTS page
↑ Eom, GH et al. (2011) Histone methyltransferase SETD3 regulates muscle differentiation. J. Biol. Chem. 286 34733-42 PubMed GONUTS page
↑ ^20.0 ^20.1 Armand, AS et al. (2008) Cooperative synergy between NFAT and MyoD regulates myogenin expression and myogenesis. J. Biol. Chem. 283 29004-10 PubMed GONUTS page
↑ Micheli, L et al. (2005) PC4 coactivates MyoD by relieving the histone deacetylase 4-mediated inhibition of myocyte enhancer factor 2C. Mol. Cell. Biol. 25 2242-59 PubMed GONUTS page
↑ ^22.0 ^22.1 ^22.2 Yeung, F et al. (2012) Myh7b/miR-499 gene expression is transcriptionally regulated by MRFs and Eos. Nucleic Acids Res. 40 7303-18 PubMed GONUTS page
↑ Engert, JC et al. (1995) Activation of a muscle-specific enhancer by the Ski proto-oncogene. Nucleic Acids Res. 23 2988-94 PubMed GONUTS page
↑ ^24.0 ^24.1 Anderson, DM et al. (2015) A micropeptide encoded by a putative long noncoding RNA regulates muscle performance. Cell 160 595-606 PubMed GONUTS page
↑ Long, X et al. (2007) Myocardin is a bifunctional switch for smooth versus skeletal muscle differentiation. Proc. Natl. Acad. Sci. U.S.A. 104 16570-5 PubMed GONUTS page
↑ Hawke, TJ et al. (2007) Xin, an actin binding protein, is expressed within muscle satellite cells and newly regenerated skeletal muscle fibers. Am. J. Physiol., Cell Physiol. 293 C1636-44 PubMed GONUTS page
↑ ^27.0 ^27.1 ^27.2 ^27.3 ^27.4 Meech, R et al. (2003) The homeodomain protein Barx2 promotes myogenic differentiation and is regulated by myogenic regulatory factors. J. Biol. Chem. 278 8269-78 PubMed GONUTS page
↑ Davie, JK et al. (2007) Target gene selectivity of the myogenic basic helix-loop-helix transcription factor myogenin in embryonic muscle. Dev. Biol. 311 650-64 PubMed GONUTS page
↑ Kang, JS et al. (2004) Netrins and neogenin promote myotube formation. J. Cell Biol. 167 493-504 PubMed GONUTS page
↑ Schmidt, K et al. (2003) Sox8 is a specific marker for muscle satellite cells and inhibits myogenesis. J. Biol. Chem. 278 29769-75 PubMed GONUTS page
↑ ^31.0 ^31.1 Ge, K et al. (2002) Transcription coactivator TRAP220 is required for PPAR gamma 2-stimulated adipogenesis. Nature 417 563-7 PubMed GONUTS page
↑ Rajan, S et al. (2012) Analysis of early C2C12 myogenesis identifies stably and differentially expressed transcriptional regulators whose knock-down inhibits myoblast differentiation. Physiol. Genomics 44 183-97 PubMed GONUTS page
↑ Millay, DP et al. (2014) Myomaker is essential for muscle regeneration. Genes Dev. 28 1641-6 PubMed GONUTS page
↑ Castets, P et al. (2011) Satellite cell loss and impaired muscle regeneration in selenoprotein N deficiency. Hum. Mol. Genet. 20 694-704 PubMed GONUTS page
↑ Dyson, PJ et al. (1992) Mapping of the genes encoding tum- transplantation antigens P91A, P35B, and P198. Immunogenetics 35 316-23 PubMed GONUTS page
↑ Kong, Y et al. (1997) Muscle LIM protein promotes myogenesis by enhancing the activity of MyoD. Mol. Cell. Biol. 17 4750-60 PubMed GONUTS page
↑ Rudnicki, MA et al. (1993) MyoD or Myf-5 is required for the formation of skeletal muscle. Cell 75 1351-9 PubMed GONUTS page
↑ Inanlou, MR & Kablar, B (2003) Abnormal development of the diaphragm in mdx:MyoD-/-(9th) embryos leads to pulmonary hypoplasia. Int. J. Dev. Biol. 47 363-71 PubMed GONUTS page
↑ Sambasivan, R et al. (2009) Distinct regulatory cascades govern extraocular and pharyngeal arch muscle progenitor cell fates. Dev. Cell 16 810-21 PubMed GONUTS page
↑ Günther, S et al. (2004) VITO-1 is an essential cofactor of TEF1-dependent muscle-specific gene regulation. Nucleic Acids Res. 32 791-802 PubMed GONUTS page
↑ Brent, AE et al. (2005) Genetic analysis of interactions between the somitic muscle, cartilage and tendon cell lineages during mouse development. Development 132 515-28 PubMed GONUTS page
↑ Lee, H et al. (2004) MSX1 cooperates with histone H1b for inhibition of transcription and myogenesis. Science 304 1675-8 PubMed GONUTS page
↑ ^43.0 ^43.1 Nishiyama, A et al. (2009) Uncovering early response of gene regulatory networks in ESCs by systematic induction of transcription factors. Cell Stem Cell 5 420-33 PubMed GONUTS page
↑ Cheung, TH et al. (2012) Maintenance of muscle stem-cell quiescence by microRNA-489. Nature 482 524-8 PubMed GONUTS page
↑ Holst, D et al. (2003) Roles of peroxisome proliferator-activated receptors delta and gamma in myoblast transdifferentiation. Exp. Cell Res. 288 168-76 PubMed GONUTS page
↑ Liu, D et al. (2001) TGF-beta inhibits muscle differentiation through functional repression of myogenic transcription factors by Smad3. Genes Dev. 15 2950-66 PubMed GONUTS page
↑ Rahib, L et al. (2009) Transcriptomic and network component analysis of glycerol kinase in skeletal muscle using a mouse model of glycerol kinase deficiency. Mol. Genet. Metab. 96 106-12 PubMed GONUTS page
↑ Bowlin, KM et al. () Kbtbd5 is regulated by MyoD and restricted to the myogenic lineage. Differentiation 86 184-91 PubMed GONUTS page
↑ ^49.0 ^49.1 Ichida, M et al. (1998) MyoD is indispensable for muscle-specific alternative splicing in mouse mitochondrial ATP synthase gamma-subunit pre-mRNA. J. Biol. Chem. 273 8492-501 PubMed GONUTS page
↑ ^50.0 ^50.1 ^50.2 Weintraub, H et al. (1991) The myoD gene family: nodal point during specification of the muscle cell lineage. Science 251 761-6 PubMed GONUTS page

[PMID:22740650-1] 1.0 ^1.1 Busanello, A et al. (2012) MyoD regulates p57kip2 expression by interacting with a distant cis-element and modifying a higher order chromatin structure. Nucleic Acids Res. 40 8266-75 PubMed GONUTS page

[PMID:25217815-2] 2.0 ^2.1 Grifone, R et al. (2014) The RNA-binding protein Rbm24 is transiently expressed in myoblasts and is required for myogenic differentiation during vertebrate development. Mech. Dev. 134 1-15 PubMed GONUTS page

[PMID:16901893-3] 3.0 ^3.1 ^3.2 Wilson, EM & Rotwein, P (2006) Control of MyoD function during initiation of muscle differentiation by an autocrine signaling pathway activated by insulin-like growth factor-II. J. Biol. Chem. 281 29962-71 PubMed GONUTS page

[PMID:16245309-4] Giacinti, C et al. (2006) MyoD recruits the cdk9/cyclin T2 complex on myogenic-genes regulatory regions. J. Cell. Physiol. 206 807-13 PubMed GONUTS page

[PMID:12037670-5] Simone, C et al. (2002) Activation of MyoD-dependent transcription by cdk9/cyclin T2. Oncogene 21 4137-48 PubMed GONUTS page

[PMID:11714687-6] Wang, DZ et al. (2001) The Mef2c gene is a direct transcriptional target of myogenic bHLH and MEF2 proteins during skeletal muscle development. Development 128 4623-33 PubMed GONUTS page

[PMID:20833138-7] 7.0 ^7.1 Choi, J et al. (2010) Histone demethylase LSD1 is required to induce skeletal muscle differentiation by regulating myogenic factors. Biochem. Biophys. Res. Commun. 401 327-32 PubMed GONUTS page

[PMID:15706034-8] 8.0 ^8.1 ^8.2 ^8.3 ^8.4 ^8.5 Blais, A et al. (2005) An initial blueprint for myogenic differentiation. Genes Dev. 19 553-69 PubMed GONUTS page

[PMID:21556048-9] 9.0 ^9.1 Al Madhoun, AS et al. (2011) Skeletal myosin light chain kinase regulates skeletal myogenesis by phosphorylation of MEF2C. EMBO J. 30 2477-89 PubMed GONUTS page

[PMID:2503252-10] 10.0 ^10.1 ^10.2 Murre, C et al. (1989) Interactions between heterologous helix-loop-helix proteins generate complexes that bind specifically to a common DNA sequence. Cell 58 537-44 PubMed GONUTS page

[PMID:20139084-11] Stuelsatz, P et al. (2010) Down-regulation of MyoD by calpain 3 promotes generation of reserve cells in C2C12 myoblasts. J. Biol. Chem. 285 12670-83 PubMed GONUTS page

[PMID:21873635-12] 12.0 ^12.1 ^12.2 ^12.3 ^12.4 ^12.5 ^12.6 ^12.7 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:15890200-13] 13.0 ^13.1 ^13.2 Bean, C et al. (2005) The Ankrd2, Cdkn1c and calcyclin genes are under the control of MyoD during myogenic differentiation. J. Mol. Biol. 349 349-66 PubMed GONUTS page

[PMID:19319192-14] 14.0 ^14.1 ^14.2 ^14.3 ^14.4 ^14.5 ^14.6 ^14.7 ^14.8 Lagirand-Cantaloube, J et al. (2009) Inhibition of atrogin-1/MAFbx mediated MyoD proteolysis prevents skeletal muscle atrophy in vivo. PLoS ONE 4 e4973 PubMed GONUTS page

[PMID:24349514-15] Lee, H et al. (2013) MicroRNA-494, upregulated by tumor necrosis factor-α, desensitizes insulin effect in C2C12 muscle cells. PLoS ONE 8 e83471 PubMed GONUTS page

[PMID:17028574-16] 16.0 ^16.1 Duquet, A et al. (2006) Acetylation is important for MyoD function in adult mice. EMBO Rep. 7 1140-6 PubMed GONUTS page

[PMID:15572127-17] 17.0 ^17.1 Cole, F et al. (2004) Positive regulation of myogenic bHLH factors and skeletal muscle development by the cell surface receptor CDO. Dev. Cell 7 843-54 PubMed GONUTS page

[PMID:24301466-18] 18.0 ^18.1 ^18.2 ^18.3 Daou, N et al. (2013) A new role for the calcineurin/NFAT pathway in neonatal myosin heavy chain expression via the NFATc2/MyoD complex during mouse myogenesis. Development 140 4914-25 PubMed GONUTS page

[PMID:21832073-19] Eom, GH et al. (2011) Histone methyltransferase SETD3 regulates muscle differentiation. J. Biol. Chem. 286 34733-42 PubMed GONUTS page

[PMID:18676376-20] 20.0 ^20.1 Armand, AS et al. (2008) Cooperative synergy between NFAT and MyoD regulates myogenin expression and myogenesis. J. Biol. Chem. 283 29004-10 PubMed GONUTS page

[PMID:15743821-21] Micheli, L et al. (2005) PC4 coactivates MyoD by relieving the histone deacetylase 4-mediated inhibition of myocyte enhancer factor 2C. Mol. Cell. Biol. 25 2242-59 PubMed GONUTS page

[PMID:22638570-22] 22.0 ^22.1 ^22.2 Yeung, F et al. (2012) Myh7b/miR-499 gene expression is transcriptionally regulated by MRFs and Eos. Nucleic Acids Res. 40 7303-18 PubMed GONUTS page

[PMID:7659522-23] Engert, JC et al. (1995) Activation of a muscle-specific enhancer by the Ski proto-oncogene. Nucleic Acids Res. 23 2988-94 PubMed GONUTS page

[PMID:25640239-24] 24.0 ^24.1 Anderson, DM et al. (2015) A micropeptide encoded by a putative long noncoding RNA regulates muscle performance. Cell 160 595-606 PubMed GONUTS page

[PMID:17940050-25] Long, X et al. (2007) Myocardin is a bifunctional switch for smooth versus skeletal muscle differentiation. Proc. Natl. Acad. Sci. U.S.A. 104 16570-5 PubMed GONUTS page

[PMID:17855775-26] Hawke, TJ et al. (2007) Xin, an actin binding protein, is expressed within muscle satellite cells and newly regenerated skeletal muscle fibers. Am. J. Physiol., Cell Physiol. 293 C1636-44 PubMed GONUTS page

[PMID:12486129-27] 27.0 ^27.1 ^27.2 ^27.3 ^27.4 Meech, R et al. (2003) The homeodomain protein Barx2 promotes myogenic differentiation and is regulated by myogenic regulatory factors. J. Biol. Chem. 278 8269-78 PubMed GONUTS page

[PMID:17904117-28] Davie, JK et al. (2007) Target gene selectivity of the myogenic basic helix-loop-helix transcription factor myogenin in embryonic muscle. Dev. Biol. 311 650-64 PubMed GONUTS page

[PMID:15520228-29] Kang, JS et al. (2004) Netrins and neogenin promote myotube formation. J. Cell Biol. 167 493-504 PubMed GONUTS page

[PMID:12782625-30] Schmidt, K et al. (2003) Sox8 is a specific marker for muscle satellite cells and inhibits myogenesis. J. Biol. Chem. 278 29769-75 PubMed GONUTS page

[PMID:12037571-31] 31.0 ^31.1 Ge, K et al. (2002) Transcription coactivator TRAP220 is required for PPAR gamma 2-stimulated adipogenesis. Nature 417 563-7 PubMed GONUTS page

[PMID:22147266-32] Rajan, S et al. (2012) Analysis of early C2C12 myogenesis identifies stably and differentially expressed transcriptional regulators whose knock-down inhibits myoblast differentiation. Physiol. Genomics 44 183-97 PubMed GONUTS page

[PMID:25085416-33] Millay, DP et al. (2014) Myomaker is essential for muscle regeneration. Genes Dev. 28 1641-6 PubMed GONUTS page

[PMID:21131290-34] Castets, P et al. (2011) Satellite cell loss and impaired muscle regeneration in selenoprotein N deficiency. Hum. Mol. Genet. 20 694-704 PubMed GONUTS page

[PMID:1348494-35] Dyson, PJ et al. (1992) Mapping of the genes encoding tum- transplantation antigens P91A, P35B, and P198. Immunogenetics 35 316-23 PubMed GONUTS page

[PMID:9234731-36] Kong, Y et al. (1997) Muscle LIM protein promotes myogenesis by enhancing the activity of MyoD. Mol. Cell. Biol. 17 4750-60 PubMed GONUTS page

[PMID:8269513-37] Rudnicki, MA et al. (1993) MyoD or Myf-5 is required for the formation of skeletal muscle. Cell 75 1351-9 PubMed GONUTS page

[PMID:12895031-38] Inanlou, MR & Kablar, B (2003) Abnormal development of the diaphragm in mdx:MyoD-/-(9th) embryos leads to pulmonary hypoplasia. Int. J. Dev. Biol. 47 363-71 PubMed GONUTS page

[PMID:19531352-39] Sambasivan, R et al. (2009) Distinct regulatory cascades govern extraocular and pharyngeal arch muscle progenitor cell fates. Dev. Cell 16 810-21 PubMed GONUTS page

[PMID:14762206-40] Günther, S et al. (2004) VITO-1 is an essential cofactor of TEF1-dependent muscle-specific gene regulation. Nucleic Acids Res. 32 791-802 PubMed GONUTS page

[PMID:15634692-41] Brent, AE et al. (2005) Genetic analysis of interactions between the somitic muscle, cartilage and tendon cell lineages during mouse development. Development 132 515-28 PubMed GONUTS page

[PMID:15192231-42] Lee, H et al. (2004) MSX1 cooperates with histone H1b for inhibition of transcription and myogenesis. Science 304 1675-8 PubMed GONUTS page

[PMID:19796622-43] 43.0 ^43.1 Nishiyama, A et al. (2009) Uncovering early response of gene regulatory networks in ESCs by systematic induction of transcription factors. Cell Stem Cell 5 420-33 PubMed GONUTS page

[PMID:22358842-44] Cheung, TH et al. (2012) Maintenance of muscle stem-cell quiescence by microRNA-489. Nature 482 524-8 PubMed GONUTS page

[PMID:12878168-45] Holst, D et al. (2003) Roles of peroxisome proliferator-activated receptors delta and gamma in myoblast transdifferentiation. Exp. Cell Res. 288 168-76 PubMed GONUTS page

[PMID:11711431-46] Liu, D et al. (2001) TGF-beta inhibits muscle differentiation through functional repression of myogenic transcription factors by Smad3. Genes Dev. 15 2950-66 PubMed GONUTS page

[PMID:19121967-47] Rahib, L et al. (2009) Transcriptomic and network component analysis of glycerol kinase in skeletal muscle using a mouse model of glycerol kinase deficiency. Mol. Genet. Metab. 96 106-12 PubMed GONUTS page

[PMID:24361185-48] Bowlin, KM et al. () Kbtbd5 is regulated by MyoD and restricted to the myogenic lineage. Differentiation 86 184-91 PubMed GONUTS page

[PMID:9525963-49] 49.0 ^49.1 Ichida, M et al. (1998) MyoD is indispensable for muscle-specific alternative splicing in mouse mitochondrial ATP synthase gamma-subunit pre-mRNA. J. Biol. Chem. 273 8492-501 PubMed GONUTS page

[PMID:1846704-50] 50.0 ^50.1 ^50.2 Weintraub, H et al. (1991) The myoD gene family: nodal point during specification of the muscle cell lineage. Science 251 761-6 PubMed GONUTS page

[1]

[2]

[3]

[4]

[5]

[6]

[7]

[8]

[9]

[10]

[11]

[12]

[13]

[14]

[15]

[16]

[17]

[18]

[19]

[20]

[21]

[22]

[23]

[24]

[25]

[26]

[27]

[28]

[29]

[30]

[31]

[32]

[33]

[34]

[35]

[36]

[37]

[38]

[39]

[40]

[41]

[42]

[43]

[44]

[45]

[46]

[47]

[48]

[49]

[50]

MOUSE:MYOD1

Contents

Annotations

Notes

References

c

d

e

g

m

n

o

p

r

s

t

u

v

Navigation menu

Personal tools

Namespaces

Variants

Views

More

Search

Navigation

Cacao

Links

Tools