GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
|Status||Page||Date/Time||GO Term (Aspect)||Reference||Evidence||Notes||Links|
|SCHPO:DCR1||2013-03-26 12:34:04 CDT||GO:0010629 negative regulation of gene expression (P)||PMID:17981703||ECO:0000315 mutant phenotype evidence used in manual assertion|
Figure 4. Shows the relative protein expression level is increased in the Dcr1 knockout strain when compared to the wild-type strain. Lower protein expression is indicative of lower gene expression.
|MOUSE:MTM1||2013-03-30 12:05:40 CDT||GO:0046716 muscle cell homeostasis (P)||PMID:23390130||ECO:0000315 mutant phenotype evidence used in manual assertion|
Figure 2A,2B. Shows mutagenesis of Mtm1 leads to lower muscle weight and myofiber size.
|HUMAN:INSL3||2013-04-09 10:56:03 CDT||GO:0010634 positive regulation of epithelial cell migration (P)||PMID:23539510||ECO:0000314 direct assay evidence used in manual assertion|
Figure 3. Shows significant higher scratch closure rate of corneal an conjuctival epithelial cells. Under the effects of migration inhibitors scratch closure could not be induced. Under the effects of cell proliferation inhibitors scratch closure was unaffected.
|HUMAN:INSL3||2013-04-09 11:12:57 CDT||GO:0090303 positive regulation of wound healing (P)||PMID:23539510||ECO:0000314 direct assay evidence used in manual assertion|
Figure 5. Shows accelerated corneal wound healing after alkali burning. Higher concentrations of INSL3 correlate with quicker healing.
|HUMAN:CP17A||2013-04-09 12:10:27 CDT||GO:0004508 steroid 17-alpha-monooxygenase activity (F)||PMID:22170710||ECO:0000315 mutant phenotype evidence used in manual assertion|
Figure 3C. H44L, misense mutation in cytochrome b5 gene have severe deficiency in 17, 20 lyase activity compared to wild-type.
|MOUSE:SMCA4||2013-04-09 13:13:35 CDT||GO:0060805 negative regulation of trophoblast cell differentiation by transcription regulation from RNA polymerase II promoter (P)||PMID:20485553||ECO:0000315 mutant phenotype evidence used in manual assertion|
Figure 1. Shows Brg1 is required for Oct4 mRNA repression. Transcriptional regulation. Brg1 knockouts have higher levels of Oct4 mRNA.
Annotations challenged by Stanto81
|Status||Author,Group||Page||GO Term (Aspect)||Reference||Evidence||Links||Page history|
Team Gene Hackman
|STRCH:Q934F8||GO:0043581 - obsolete mycelium development (P)||PMID:22309453||ECO:0000316 genetic interaction evidence used in manual assertion||challenge||C: 3|
|SOLTU:Q9FEN7||GO:1901857 - positive regulation of cellular respiration (P)||PMID:18842826||ECO:0000314 direct assay evidence used in manual assertion||challenge||C: 2|
Team Bringin back Fanny Packs
|HUMAN:INSL3||GO:0010634 - positive regulation of epithelial cell migration (P)||PMID:23539510||ECO:0000314 direct assay evidence used in manual assertion||challenge||C: 2|
fixed by Stanto81
1 annotations fixed by Stanto81