User:Massi003

My Annotations

Status	Page	Date/Time	GO Term (Aspect)	Reference	Evidence	Notes	Links
acceptable	HUMAN:UCP2	2012-02-20 11:45:54 CST	GO:0001666 response to hypoxia (P)	PMID:22292025	ECO:0000314 direct assay evidence used in manual assertion	Fig 1B - UCP2 levels increase as levels of hypoxia increase	challenge
requireschanges	HUMAN:UCP2	2012-02-20 11:48:41 CST	GO:0006915 apoptotic process (P)	PMID:22292025	ECO:0000314 direct assay evidence used in manual assertion	Fig 3A overexpression of UCP2 under hypoxic conditions decreases levels of apoptosis	challenge
requireschanges	HUMAN:HIF1A	2012-02-20 11:51:59 CST	GO:0001666 response to hypoxia (P)	PMID:22292025	ECO:0000314 direct assay evidence used in manual assertion	Fig 1A as hypoxia occurs, levels of HIF-1alpha increase	challenge
requireschanges	ECOLI:MREB	2012-03-14 23:50:39 CDT	GO:0043164 Gram-negative-bacterium-type cell wall biogenesis (P)	PMID:19346310	ECO:0000316 genetic interaction evidence used in manual assertion	Table 1 Strain 2 MreB can tether peptidoglycan synthesis via a PBP2 pathway independently of FtsZ, producing a rod-shaped cell	challenge
requireschanges	ECOLI:FTSZ	2012-03-14 23:22:34 CDT	GO:0043164 Gram-negative-bacterium-type cell wall biogenesis (P)	PMID:19346310	ECO:0000316 genetic interaction evidence used in manual assertion	Table 1 strain 3 In the absence of MreB, FtsZ can tether and direct a generalized and evenly dispersed peptidoglycan, via a PBP2 pathway, producing a spherical-shaped cell	challenge
requireschanges	BACSU:COTZ	2012-04-13 10:53:09 CDT	GO:0031160 spore wall (C)	PMID:21665972	ECO:0000314 direct assay evidence used in manual assertion	Fig 2b CotZ is involved in the formation of the spore crust	challenge
requireschanges	BACSU:CGEA	2012-04-13 10:57:34 CDT	GO:0031160 spore wall (C)	PMID:21665972	ECO:0000314 direct assay evidence used in manual assertion	Fig 2c CgeA is involved in the formation of the spore crust	challenge
requireschanges	ECOLI:NMPC	2012-04-13 11:11:07 CDT	GO:0015288 porin activity (F)	PMID:21398480	ECO:0000314 direct assay evidence used in manual assertion	Fig 3 E.coli cells expressing nmpC were more reistant to heat and had a higher survival rate.	challenge
requireschanges	ECOLI:CLPP	2012-04-13 11:56:06 CDT	GO:0009408 response to heat (P)	PMID:21317324	ECO:0000315 mutant phenotype evidence used in manual assertion	Fig 1A deletion of clpP suppresses temperature-sensitive filamentation cells causing the cells to become elongated.	challenge
requireschanges	ECOLI:CLPX	2012-04-13 12:14:48 CDT	GO:0009408 response to heat (P)	PMID:21317324	ECO:0000315 mutant phenotype evidence used in manual assertion	Fig 1A depletion of clpX surpresses temperature-sensitive filamentation in cells causing them to be shorter.	challenge

acceptable:1
unacceptable:0
requires_changes:9
flagged:0

Annotations challenged by Massi003

Status	Author,Group	Page	GO Term (Aspect)	Reference	Evidence	Links	Page history
requireschanges	Chrispond, Team Big Mama 50000	ECOLI:SLT	GO:0071555 - cell wall organization (P)	PMID:9287002	ECO:0000316 genetic interaction evidence used in manual assertion	challenge	C: 2

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