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ECOLI:SLT
Contents
Species (Taxon ID) | Escherichia coli (strain K12). (83333) | |
Gene Name(s) | slt (synonyms: sltY) | |
Protein Name(s) | Soluble lytic murein transglycosylase
Exomuramidase Peptidoglycan lytic exotransglycosylase Slt70 | |
External Links | ||
UniProt | P0AGC3 | |
EMBL | M69185 U14003 U00096 AP009048 J01715 | |
PIR | S56616 | |
RefSeq | NP_418809.4 YP_492522.1 | |
PDB | 1QSA 1QTE 1SLY | |
PDBsum | 1QSA 1QTE 1SLY | |
ProteinModelPortal | P0AGC3 | |
SMR | P0AGC3 | |
IntAct | P0AGC3 | |
STRING | 511145.b4392 | |
CAZy | GH23 | |
PaxDb | P0AGC3 | |
PRIDE | P0AGC3 | |
EnsemblBacteria | AAC77345 BAE78381 | |
GeneID | 12931805 948908 | |
KEGG | ecj:Y75_p4276 eco:b4392 | |
PATRIC | 32124402 | |
EchoBASE | EB0943 | |
EcoGene | EG10950 | |
eggNOG | COG0741 | |
HOGENOM | HOG000275388 | |
InParanoid | P0AGC3 | |
KO | K08309 | |
OMA | VDWHERY | |
OrthoDB | EOG6S52QZ | |
PhylomeDB | P0AGC3 | |
BioCyc | EcoCyc:EG10950-MONOMER ECOL316407:JW4355-MONOMER MetaCyc:EG10950-MONOMER | |
EvolutionaryTrace | P0AGC3 | |
PRO | PR:P0AGC3 | |
Proteomes | UP000000318 UP000000625 | |
Genevestigator | P0AGC3 | |
GO | GO:0016020 GO:0030288 GO:0016837 GO:0004553 GO:0008933 GO:0071555 GO:0000270 | |
Gene3D | 1.10.1240.20 1.25.20.10 | |
InterPro | IPR023346 IPR016026 IPR012289 IPR008939 IPR008258 IPR000189 | |
Pfam | PF01464 PF14718 | |
SUPFAM | SSF48435 SSF53955 | |
PROSITE | PS00922 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
GO:0071555 |
cell wall organization |
ECO:0000316 |
UniProtKB:P0A908 UniProtKB:P41052
|
P |
Table 2 |
complete | ||||
part_of |
GO:0030288 |
outer membrane-bounded periplasmic space |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0008933 |
lytic transglycosylase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0030288 |
outer membrane-bounded periplasmic space |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0030288 |
outer membrane-bounded periplasmic space |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0009274 |
peptidoglycan-based cell wall |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0009253 |
peptidoglycan catabolic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0009253 |
peptidoglycan catabolic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0009253 |
peptidoglycan catabolic process |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0009253 |
peptidoglycan catabolic process |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0009253 |
peptidoglycan catabolic process |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0008933 |
lytic transglycosylase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0008933 |
lytic transglycosylase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0008933 |
lytic transglycosylase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0008932 |
lytic endotransglycosylase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0000270 |
peptidoglycan metabolic process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0004553 |
hydrolase activity, hydrolyzing O-glycosyl compounds |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0008933 |
lytic transglycosylase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0016020 |
membrane |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0042597 |
periplasmic space |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0016829 |
lyase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0042597 |
periplasmic space |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0071555 |
cell wall organization |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Lommatzsch, J et al. (1997) Outer membrane localization of murein hydrolases: MltA, a third lipoprotein lytic transglycosylase in Escherichia coli. J. Bacteriol. 179 5465-70 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Engel, H et al. (1991) Murein-metabolizing enzymes from Escherichia coli: sequence analysis and controlled overexpression of the slt gene, which encodes the soluble lytic transglycosylase. J. Bacteriol. 173 6773-82 PubMed GONUTS page
- ↑ Han, MJ et al. (2014) Comparison of the large-scale periplasmic proteomes of the Escherichia coli K-12 and B strains. J. Biosci. Bioeng. 117 437-42 PubMed GONUTS page
- ↑ Lopez-Campistrous, A et al. (2005) Localization, annotation, and comparison of the Escherichia coli K-12 proteome under two states of growth. Mol. Cell Proteomics 4 1205-9 PubMed GONUTS page
- ↑ Walderich, B & Höltje, JV (1991) Subcellular distribution of the soluble lytic transglycosylase in Escherichia coli. J. Bacteriol. 173 5668-76 PubMed GONUTS page
- ↑ Templin, MF et al. (1992) A murein hydrolase is the specific target of bulgecin in Escherichia coli. J. Biol. Chem. 267 20039-43 PubMed GONUTS page
- ↑ 7.0 7.1 Beachey, EH et al. (1981) Exoenzymatic activity of transglycosylase isolated from Escherichia coli. Eur. J. Biochem. 116 355-8 PubMed GONUTS page
- ↑ 8.0 8.1 Höltje, JV et al. (1975) Novel type of murein transglycosylase in Escherichia coli. J. Bacteriol. 124 1067-76 PubMed GONUTS page
- ↑ Cho, H et al. (2014) Beta-lactam antibiotics induce a lethal malfunctioning of the bacterial cell wall synthesis machinery. Cell 159 1300-11 PubMed GONUTS page
- ↑ 10.0 10.1 Lee, M et al. (2013) Reactions of all Escherichia coli lytic transglycosylases with bacterial cell wall. J. Am. Chem. Soc. 135 3311-4 PubMed GONUTS page