User:Cmthomas4

My Annotations

Status	Page	Date/Time	GO Term (Aspect)	Reference	Evidence	Notes	Links
unacceptable	SINMM:F7X5V0	2013-09-15 12:50:43 CDT	GO:0010468 regulation of gene expression (P)	PMID:23516427	ECO:0000315 mutant phenotype evidence used in manual assertion	Under the headline "Global Nitrogen Stress Response" you will find the information how the GlnD protein and some mutations of this protein relate to gene expression of different metabolisms and general stress responses. Figure 5 also shows the role of GlnD in general stress response through the PII protein system.	challenge
unacceptable	VIBF1:Q5E6P1	2013-09-26 16:28:54 CDT	GO:0006355 regulation of transcription, DNA-dependent (P)	PMID:23549919	ECO:0000315 mutant phenotype evidence used in manual assertion	Figure 7a shows the effects of fur on a number of transcriptional factors.	challenge
unacceptable	VIBF1:Q5E6P1	2013-09-26 16:32:36 CDT	GO:0003677 DNA binding (F)	PMID:23549919	ECO:0000247 sequence alignment evidence used in manual assertion	Figure 6 shows integration points into target genome by fur.	challenge
updatedbyinstructor	HUMAN:CCR1	2013-09-26 17:18:01 CDT	GO:0030335 positive regulation of cell migration (P)	PMID:24056371	ECO:0000315 mutant phenotype evidence used in manual assertion	Figure 1	challenge
unacceptable	MOUSE:CD36	2013-09-26 17:54:01 CDT	GO:0006911 phagocytosis, engulfment (P)	PMID:24058538	ECO:0000314 direct assay evidence used in manual assertion	Page 13 describes the roll of CD36 in engulfment of pathogens in the cells of mice.	challenge
acceptable	MOUSE:TFF3	2013-10-08 09:54:47 CDT	GO:0010906 regulation of glucose metabolic process (P)	PMID:24086476	ECO:0000314 direct assay evidence used in manual assertion	Figures 3,4, and 5 show how Tff3 regulates glucose metabolism by decreasing the amount of blood glucose and increases glucose tolerance in different types of mice.	challenge
unacceptable	?	2013-10-08 10:19:44 CDT	GO:0050994 regulation of lipid catabolic process (Figure 4 shows how mutations to prx-5 influence Monomethyl branched-chain fatty acid degradation. )	PMID:24086720	IMP: Inferred from Mutant Phenotype		challenge
unacceptable	MOUSE:CXCL9	2013-10-08 10:39:24 CDT	GO:0006935 chemotaxis (P)	PMID:24083082	ECO:0000314 direct assay evidence used in manual assertion	Figure 5 illustrates the effect of CXCL9 knockout influences the distribution of Tcell subsets in mice.	challenge
unacceptable	RHORU:DRAT	2013-11-05 09:16:47 CST	GO:0006471 protein ADP-ribosylation (P)	PMID:23144248	ECO:0000314 direct assay evidence used in manual assertion	Figure 2 shows activation and interaction with different PII proteins that form in vitro complexes and the Fe protein. Fe protein activity, and thus, DraT activity was measured by the evolution of hydrogen.	challenge
unacceptable	HUMAN:A3KMG8	2013-11-05 10:28:00 CST	GO:0010468 regulation of gene expression (P)	PMID:24174533	ECO:0000314 direct assay evidence used in manual assertion	Figure 2 shows the effects of ZMIZ2 on the Cyclin D1-promoter in HEK29 in media containing various shRNA constructs. Promoter activity was observed by measuring the luciferase and B-gal activities of the cells.	challenge
unacceptable	HUMAN:PIN1	2013-11-05 11:10:48 CST	GO:0045967 negative regulation of growth rate (P)	PMID:24179535	ECO:0000314 direct assay evidence used in manual assertion	Figure 3(A) shows the effect of PIN1 on the growth rate of siRNA-transfected RBE cells.	challenge
updatedbyinstructor	MOUSE:ISL1	2013-11-05 11:35:36 CST	GO:0035066 positive regulation of histone acetylation (P)	PMID:24147056	ECO:0000315 mutant phenotype evidence used in manual assertion	Figure 5 shows the effect of Islet-1 on the acetylation levels of histone H3 compared to the acetylation levels of H3 in progenitor cells.	challenge
unacceptable	SALTI:Q8Z8M2	2013-11-05 11:58:06 CST	GO:1901311 regulation of gene expression involved in extracellular matrix organization (P)	PMID:24169580	ECO:0000315 mutant phenotype evidence used in manual assertion	Figure 2 shows the effect on RamA levels of removing the inducer of RamA (chlorpromazine). Half-life of RamA was also determined in absence of chlorpromazine.	challenge

acceptable:1
unacceptable:10
requires_changes:0
flagged:0

Annotations challenged by Cmthomas4

Status	Author,Group	Page	GO Term (Aspect)	Reference	Evidence	Links	Page history

0 annotations fixed by Cmthomas4

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